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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition

CYTARABINE-1GM

Manufacturer/Marketer

Pfizer Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About CYTOSAR 1GM INJECTION 10ML

CYTOSAR 1GM INJECTION 10ML is an anticancer medicine used in the treatment of leukemia. Leukemia, also known as blood cancer, is a cancer of blood cells or blood-forming tissues. It causes excessive production of immature white blood cells by the bone marrow and reduces the body’s ability to fight infections. CYTOSAR 1GM INJECTION 10ML is used in the treatment of different types of leukemias, such as acute non-lymphocytic leukemia, acute lymphocytic leukemia, chronic myelocytic leukemia and meningeal leukemia.

CYTOSAR 1GM INJECTION 10ML contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for the growth, repair and multiplication of cells. Thus, CYTOSAR 1GM INJECTION 10ML stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

CYTOSAR 1GM INJECTION 10ML may cause certain side effects such as vomiting, nausea, mouth ulcers, loss of appetite, diarrhea, dark-coloured urine, stomach pain, hair loss, dizziness, weakness, and pain at the site of injection, prescribed by your doctor. Most of these side effects of CYTOSAR 1GM INJECTION 10ML do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please seek medical help. A trained healthcare professional will administer CYTOSAR 1GM INJECTION 10ML. Hence, do not self-administer.

If you are allergic to CYTOSAR 1GM INJECTION 10ML, inform your doctor and avoid taking it. Inform your doctor about your complete medical and medication history before starting treatment with CYTOSAR 1GM INJECTION 10ML. CYTOSAR 1GM INJECTION 10ML is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had kidney or liver disease. Avoid alcohol consumption with CYTOSAR 1GM INJECTION 10ML as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as CYTOSAR 1GM INJECTION 10ML may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out.

Uses of CYTOSAR 1GM INJECTION 10ML

Chronic myeloid leukemia, Acute lymphocytic leukemia, Acute non-lymphocytic leukemia, and meningeal leukemia.

Directions for Use

Your oncology doctor will administer CYTOSAR 1GM INJECTION 10ML. Hence, do not self-administer.

Medicinal Benefits

CYTOSAR 1GM INJECTION 10ML contains Cytarabine, which belongs to the class of antimetabolites. It works by inhibiting the DNA polymerase enzyme that is responsible for DNA elongation, synthesis, and repair. In general, it inhibits the production of genetic material (DNA) in the cancer cells that are essential for cell growth, repair and multiplication. Thus, CYTOSAR 1GM INJECTION 10ML stops the multiplication of abnormal cells, leads to the growth of cells in an unbalanced way and causes the death of cells.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CYTOSAR 1GM INJECTION 10ML

  • Vomiting
  • Nausea
  • Mouth ulcers
  • Loss of appetite
  • Diarrhoea
  • Dark-coloured urine
  • Dizziness
  • Confusion
  • Stomach pain
  • Weakness
  • Injection site reactions
  • Pain at the site of injection

Drug Warnings

CYTOSAR 1GM INJECTION 10ML should be avoided if you are allergic to it or any other component present in it. Inform your doctor about your complete medical and medication history before starting treatment with CYTOSAR 1GM INJECTION 10ML. CYTOSAR 1GM INJECTION 10ML is contraindicated for pregnant women and breastfeeding women due to serious embryo-fetal toxicity. Hence, inform your doctor if you are pregnant, planning to become pregnant or breastfeeding. Inform your doctor if you have/had any pre-existing liver or kidney disease. Avoid taking CYTOSAR 1GM INJECTION 10ML if you are pregnant, as it may harm the foetus. Avoid alcohol consumption with CYTOSAR 1GM INJECTION 10ML as it may increase the risk of liver damage. Avoid excessive exposure to sunlight as CYTOSAR 1GM INJECTION 10ML may cause sensitivity to sunlight. You are advised to use sunscreen and wear protective clothing while going out. If you are about to receive any vaccinations, inform your doctor that you are taking CYTOSAR 1GM INJECTION 10ML as it may cause infection.

Drug-Drug Interactions

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CytarabineInfliximab
Severe
CytarabineThalidomide
Severe

Drug-Drug Interactions

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CytarabineInfliximab
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
Combining Infliximab with Cytosar 1 gm Injection 10 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Cytosar 1 gm Injection 10 ml with Infliximab can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CytarabineThalidomide
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
Taking thalidomide together with Cytosar 1 gm Injection 10 ml may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Cytosar 1 gm Injection 10 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
CytarabineTofacitinib
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
Taking Tofacitinib with Cytosar 1 gm Injection 10 ml may increase the risk of serious infection.

How to manage the interaction:
Taking Tofacitinib with Cytosar 1 gm Injection 10 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.
CytarabineBaricitinib
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
Coadministration of Cytosar 1 gm Injection 10 ml with Baricitinib can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Cytosar 1 gm Injection 10 ml and Baricitinib, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CytarabineKetoconazole
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
Taking Cytosar 1 gm Injection 10 ml with Ketoconazole can increase the risk of liver damage.

How to manage the interaction:
Although there is a possible interaction between Cytosar 1 gm Injection 10 ml and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
CytarabineClozapine
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
Combining Cytosar 1 gm Injection 10 ml with Clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Cytosar 1 gm Injection 10 ml and Clozapine, but it can be taken if prescribed by a doctor. If you notice any of these symptoms - such as fever, sore throat, or muscle aches - contact your doctor immediately. Do not stop using any medications without talking to a doctor.
CytarabineCladribine
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
The combined use of cladribine with Cytosar 1 gm Injection 10 ml can increase the risk and severity of side effects.

How to manage the interaction:
Although taking Cytosar 1 gm Injection 10 ml and Cladribine together can evidently cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you pee. Do not stop using any medications without a doctor's advice.
CytarabineEtanercept
Severe
How does the drug interact with Cytosar 1 gm Injection 10 ml:
When Etanercept is used with Cytosar 1 gm Injection 10 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Taking Cytosar 1 gm Injection 10 ml with Etanercept together can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily while taking CYTOSAR 1GM INJECTION 10ML as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

CYTOSAR 1GM INJECTION 10ML Substitute

Substitutes safety advice
  • CYTARINE INJECTION 1GM

    by Others

    392.50per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • MESALAZINE
  • OLSALAZINE
  • SULFASALAZINE
  • GENTAMICIN
  • AMIKACIN
  • CHOLERA VACCINE
  • TYPHOID VACCINE

Special Advise

  • Regular blood tests are recommended while taking CYTOSAR 1GM INJECTION 10ML to monitor the number and type of cells in the blood. 
  • CYTOSAR 1GM INJECTION 10ML, like other cytotoxic medicines, can cause hyperuricemia due to the fast lysis of neoplastic cells. Blood uric acid levels should be monitored and be ready to utilize any supportive or pharmacologic interventions that may be required to address this condition.

Disease/Condition Glossary

Chronic myeloid leukemia: It is a type of cancer that occurs in the bone marrow and blood. It abnormally increases the number of immature white blood cells. The symptoms include unexplained weight loss, excessive sweating, bone pain, frequent nosebleeds, heavier-than-normal periods in females, and shortness of breath. The risk factors include smoking and genetic or blood disorders.

Acute lymphocytic leukemia: It is a type of cancer that occurs in the bone marrow and blood. It increases the number of lymphocytes (a type of white blood cell). The symptoms include fever, enlarged liver, bone or joint pain, shortness of breath, weakness, and bleeding from gums or bruises.

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