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DACAREX 200MG INJECTION

DACAREX 200MG INJECTION

Consult Doctor
Prescription drug
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Manufacturer/Marketer

Alkem Laboratories Ltd

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About DACAREX 200MG INJECTION

DACAREX 200MG INJECTION is a chemotherapeutic medicine used in the treatment of skin cancer. Cancer is a condition where the cells grow and reproduce uncontrollably in a specific body part. These cancerous cells can attack and destroy surrounding healthy tissue and organs. DACAREX 200MG INJECTION is used in the treatment of metastatic malignant melanoma. It is a serious condition in which the cancer grows in melanocytes and also spreads to other parts of the body. DACAREX 200MG INJECTION is also used as a second-line therapy in the treatment of Hodgkin’s Disease when used in combination with other approved drugs.

DACAREX 200MG INJECTION contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

DACAREX 200MG INJECTION may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. DACAREX 200MG INJECTION is a parenteral preparation. A trained healthcare professional will administer it. 

DACAREX 200MG INJECTION should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including medications you take, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or heart problems. DACAREX 200MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring of blood and liver functioning should be done during the entire treatment. This medicine is known to cause fetal harm if used in pregnancy. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding before taking DACAREX 200MG INJECTION.

Uses of DACAREX 200MG INJECTION

Metastatic Malignant Melanoma, Hodgkin’s Disease.

Medicinal Benefits

DACAREX 200MG INJECTION contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

Directions for Use

DACAREX 200MG INJECTION will be administered by a trained healthcare professional. Hence, do not self-administer. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of DACAREX 200MG INJECTION

  • Nausea
  • Dizziness
  • Fever
  • Chills
  • Sore throat
  • Headache
  • Vomiting
  • Cough
  • Decreased platelet count
  • Bruising or bleeding gums
  • Pain at the site of injection

Drug Warnings

DACAREX 200MG INJECTION should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or cardiac disorders. DACAREX 200MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women and breastfeeding mothers. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. It is unknown whether DACAREX 200MG INJECTION can be administered to children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug Interactions

Drug-Drug Interactions: DACAREX 200MG INJECTION may interact with vaccines, antiretroviral drugs (Abacavir, Zidovudine, adefovir), immunomodulators (Abatacept, Enteracept), anticoagulants (acenocoumarol, warfarin), anticonvulsant drugs (phenytoin, phenobarbitone).

Drug-Food Interactions: Avoid alcohol consumption and smoking. 

Drug-Disease Interactions:  Inform your doctor if you have kidney or liver disease, gastrointestinal disorders,  and hemopoietic depression before receiving DACAREX 200MG INJECTION.

Drug-Drug Interactions Checker List

  • ABACAVIR
  • ZIDOVUDINE
  • ADEFOVIR
  • WARFARIN
  • ACENOCOUMAROL
  • PHENYTOIN
  • ABATACEPT

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Avoid going out in the hot sun, as it can harm your skin.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.

Special Advise

  • DACAREX 200MG INJECTION should be administered only by a trained and experienced oncologist.
  • A blood test should be performed, such as LFT and RFT, to check for liver/ and kidney function.
  • Weekly blood tests should be done for after the dose is administered to check for CBC (Complete blood count).

Disease/Condition Glossary

Metastatic Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. When the cancer cells spread to other parts of the body, it is known as Metastasis. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face. 

Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells, causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.

Country of origin

India

Manufacturer/Marketer address

Alkem Laboratories Limited, Devashish Building, Alkem House, Senapati Bapat Road, Lower Parel, Mumbai - 400 013.
Other Info - DAC0002

FAQs

DACAREX 200MG INJECTION contains Dacarbazine, which belongs to the alkylating agents class. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis.
DACAREX 200MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, inform your oncologist about your complete medical history, including current medication, to rule out any side effects/interactions.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

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Alcohol

Unsafe

Avoid alcohol consumption while on treatment with DACAREX 200MG INJECTION to prevent serious side effects.

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Pregnancy

Unsafe

DACAREX 200MG INJECTION is not recommended for use in pregnancy as it may harm your fetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving DACAREX 200MG INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving DACAREX 200MG INJECTION. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Caution

DACAREX 200MG INJECTION will be administered in the hospital setting. Hence, driving is not recommended.

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before receiving DACAREX 200MG INJECTION. It may cause hepatic necrosis when administered with other antineoplastics. Hence, DACAREX 200MG INJECTION should be used with caution in patients with liver problems. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before receiving DACAREX 200MG INJECTION. It should be used with caution in patients with renal impairment. A dose adjustment of this medicine or a suitable alternative may be advised based on your condition.

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Children

Consult your doctor

Limited information is available for the use of DACAREX 200MG INJECTION in children. It will be administered to the children only if clearly needed. If administered, careful monitoring of the child is needed.

Author Details

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