DACAREX 500MG INJECTION is a chemotherapeutic medicine used in the treatment of skin cancer. Cancer is a condition where the cells grow and reproduce uncontrollably in a specific body part. These cancerous cells can attack and destroy surrounding healthy tissue and organs. DACAREX 500MG INJECTION is used in the treatment of metastatic malignant melanoma. It is a serious condition in which the cancer grows in melanocytes and also spreads to other parts of the body. DACAREX 500MG INJECTION is also used as a second-line therapy in the treatment of Hodgkin’s Disease when used in combination with other approved drugs.

DACAREX 500MG INJECTION contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

DACAREX 500MG INJECTION may cause certain side effects, such as nausea, vomiting, headache, dizziness, and pain at the site of injection. These side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. DACAREX 500MG INJECTION is a parenteral preparation. A trained healthcare professional will administer it. 

DACAREX 500MG INJECTION should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including medications you take, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or heart problems. DACAREX 500MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring of blood and liver functioning should be done during the entire treatment. This medicine is known to cause fetal harm if used in pregnancy. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding before taking DACAREX 500MG INJECTION.

DACAREX 500MG INJECTION contains Dacarbazine, which belongs to the class of alkylating agents. It works by inhibiting the DNA and RNA transcription that is essential for protein synthesis. This helps prevent the growth and further spread of cancerous or non-cancerous cells.

• Nausea
• Dizziness
• Fever
• Chills
• Sore throat
• Headache
• Vomiting
• Cough
• Decreased platelet count
• Bruising or bleeding gums
• Pain at the site of injection

DACAREX 500MG INJECTION should be avoided if you are allergic to it or any other components present in it. Let your doctor know about your complete medical history, including current medication, to rule out any side effects/interactions. Before administration, inform your doctor if you have liver/kidney disease or cardiac disorders. DACAREX 500MG INJECTION may cause hemopoietic (bone marrow) depression, hepatic toxicity, and hepatic necrosis in some patients. Hence, careful monitoring should be done during the entire treatment. This medicine is known to cause fetal harm in pregnant women and breastfeeding mothers. Hence, inform your doctor if you are pregnant, planning to become pregnant and breastfeeding. It is unknown whether DACAREX 500MG INJECTION can be administered to children or not. If administered, close monitoring of the child is needed. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Drug-Drug Interactions: DACAREX 500MG INJECTION may interact with vaccines, antiretroviral drugs (Abacavir, Zidovudine, adefovir), immunomodulators (Abatacept, Enteracept), anticoagulants (acenocoumarol, warfarin), anticonvulsant drugs (phenytoin, phenobarbitone).

Drug-Food Interactions: Avoid alcohol consumption and smoking. 

Drug-Disease Interactions:  Inform your doctor if you have kidney or liver disease, gastrointestinal disorders,  and hemopoietic depression before receiving DACAREX 500MG INJECTION.

• ABACAVIR
• ZIDOVUDINE
• ADEFOVIR
• WARFARIN
• ACENOCOUMAROL
• PHENYTOIN
• ABATACEPT

• Eat a healthy diet and exercise regularly to maintain proper weight.
• Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
• Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
• De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
• Avoid going out in the hot sun, as it can harm your skin.
• Get optimal sleep; rest well.
• Avoid smoking and alcohol consumption.

• DACAREX 500MG INJECTION should be administered only by a trained and experienced oncologist.
• A blood test should be performed, such as LFT and RFT, to check for liver/ and kidney function.
• Weekly blood tests should be done for after the dose is administered to check for CBC (Complete blood count).

Metastatic Malignant Melanoma: Melanoma is a type of skin cancer in which the cancer cells grow in melanocytes. It is mainly caused by harmful UV radiation from the sun. When the cancer cells spread to other parts of the body, it is known as Metastasis. Malignant melanoma is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face. 

Hodgkin’s Disease: Hodgkin’s disease or lymphoma is a blood cancer of a certain type of cells called WBCs, specifically lymphocytes. Lymphocytes normally help control infection and maintain the body's normal immunity. However, in a cancerous state, there is an abnormal multiplication of these blood cells, causing many problems such as fatigue, fever, loss of appetite, itching, night sweats and lymph node swelling.