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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Dacotin Rtu-100 Injection 20 ml

Dacotin Rtu-100 Injection 20 ml belongs to the group of medicines called platinum-containing antineoplastic agents used alone or in combination with other anti-cancer medicines to treat cancer of the large bowel/intestine (advanced colon or colorectal cancer). 
 
Dacotin Rtu-100 Injection 20 ml contains Oxaliplatin, which works by killing the cancer cells. Thereby, it helps treat cancer.
 
In some cases, Dacotin Rtu-100 Injection 20 ml may cause side effects such as mild nausea, vomiting, diarrhoea, fever, and headache. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Dacotin Rtu-100 Injection 20 ml if you are breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Dacotin Rtu-100 Injection 20 ml. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Dacotin Rtu-100 Injection 20 ml

Colon and rectal cancer

Directions for Use

Dacotin Rtu-100 Injection 20 ml will be administered by a qualified physician; do not self-administer.

Medicinal Benefits

Dacotin Rtu-100 Injection 20 ml contains Oxaliplatin, which belongs to the group of medicines called platinum-containing antineoplastic agents used to treat stage III colon cancer after complete removal of the primary tumour and metastatic cancer of the colon and rectum. It is used in combination with other anti-cancer medicines, such as 5-fluorouracil and folinic acid. Dacotin Rtu-100 Injection 20 ml works by killing the cancer cells. Thereby, it helps treat cancer. Dacotin Rtu-100 Injection 20 ml may also be used with other medicines to prevent colon cancer from spreading in patients who have had surgery to remove the tumour.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dacotin Rtu-100 Injection 20 ml

  • Mild nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Peripheral neuropathy
  • Fatigue
  • Back pain
  • Stomach pain

Drug Warnings

Do not use Dacotin Rtu-100 Injection 20 ml if you are allergic to any of its components, if you are breastfeeding, have a low blood cell count, have severe kidney problems, tingling and numbness in the fingers/toes, and have difficulty performing fragile tasks, such as buttoning clothes. Inform the doctor if you ever suffered an allergic reaction to platinum-containing medicines, have mild/moderate kidney problems, liver problems or abnormal liver function tests during therapy, or heart disorders like prolongation of the QT interval (abnormal electrical signal), an irregular heartbeat, or a family history of heart problems. Seek immediate medical attention if you experience symptoms of an allergic reaction (rash, itching, hives, reddening of the skin, hoarseness, difficulty breathing or swallowing, feeling as if your throat is closing, dizziness, swelling of the lips and tongue, lightheadedness, or fainting), unpleasant sensation in the throat, rhabdomyolysis (muscle pain and swelling), nerve problems (sensitivity to cold temperature or cold objects, pain, tingling or burning sensation), Posterior Reversible Encephalopathy Syndrome (headache, confusion, seizures, vision problems), myelosuppression (chills or shivering, burning or pain on urination, pain on swallowing, sore throat, cough with mucus, persistent diarrhoea), lung problems (shortness of breath, wheezing, cough), or bleeding problems (vomit that looks like coffee grounds or bloody vomit, pink or brown urine, weakness, dizziness, changes in speech, confusion, unexplained bleeding or dark-coloured/tarry stools).

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
OxaliplatinHaloperidol
Severe

Drug-Drug Interactions

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OxaliplatinZiprasidone
Critical
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Combining Dacotin Rtu-100 Injection 20 ml with Ziprasidone can increase the risk of QTc prolongation.

How to manage the interaction:
Taking Dacotin Rtu-100 Injection 20 ml with Ziprasidone is not recommended, please consult your doctor before taking it.
OxaliplatinHaloperidol
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Co-administration of Dacotin Rtu-100 Injection 20 ml and Haloperidol can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Co-administration of Dacotin Rtu-100 Injection 20 ml and Haloperidol can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
OxaliplatinMifepristone
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Co-administration of Dacotin Rtu-100 Injection 20 ml with mifepristone can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Dacotin Rtu-100 Injection 20 ml with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
OxaliplatinChloroquine
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Using chloroquine together with Dacotin Rtu-100 Injection 20 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chloroquine and Dacotin Rtu-100 Injection 20 ml together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
OxaliplatinHydroxychloroquine
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
The combined use of Dacotin Rtu-100 Injection 20 ml and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of oxalipatin and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
OxaliplatinAmisulpride
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Using amisulpride together with Dacotin Rtu-100 Injection 20 ml can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Co-administration of Dacotin Rtu-100 Injection 20 ml with Amisulpride can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
OxaliplatinBaricitinib
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Coadministration of baricitinib and Dacotin Rtu-100 Injection 20 ml can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Dacotin Rtu-100 Injection 20 ml if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
OxaliplatinCeritinib
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Taking Dacotin Rtu-100 Injection 20 ml with ceritinib can increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Dacotin Rtu-100 Injection 20 ml and Ceritinib, but it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms such as dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
OxaliplatinGatifloxacin
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Taking Dacotin Rtu-100 Injection 20 ml with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dacotin Rtu-100 Injection 20 ml with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OxaliplatinCladribine
Severe
How does the drug interact with Dacotin Rtu-100 Injection 20 ml:
Combining Cladribine with Dacotin Rtu-100 Injection 20 ml can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Dacotin Rtu-100 Injection 20 ml and Cladribine, you can take these medicines together if prescribed by your doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Dacotin Rtu-100 Injection 20 ml Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Special Advise

  • Women must use reliable contraception during treatment and for nine months after receiving the last dose.
  • Male patients are advised not to father a child during treatment and for six months after the last dose. Use effective contraception during this time.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Dacotin Rtu-100 Injection 20 ml.
  • Avoid eating or drinking anything that is colder than room temperature for five days after receiving each dose of Dacotin Rtu-100 Injection 20 ml. To reduce side effects caused by cold temperature-cover yourself with a blanket while getting treatment with Dacotin Rtu-100 Injection 20 ml, wear warm clothing in cold weather at all times, cover your mouth and nose with a scarf and wear gloves whilst touching cold objects. Drink fluid at room/warm temperature and always drink through a straw. Avoid using ice and AC, touching cold metals, and breathing deeply when exposed to cold air.

Disease/Condition Glossary

Colon and rectal cancer: It is a cancer of the colon or rectum. Colorectal cancer is the growth of cells that form in the lower end of the digestive tract. Most of these cancers begin as polyps (non-cancerous growths). Symptoms may include abdominal discomfort, blood in the stool, and changes in bowel habits like constipation or diarrhoea.

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