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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Whats That

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Composition :

KETOCONAZOLE-200MG

Manufacturer/Marketer :

Carlton Dermatology

Consume Type :

ORAL

Return Policy :

Not Returnable

About Dandrotin 200mg Tablet

Dandrotin 200mg Tablet belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Dandrotin 200mg Tablet contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Dandrotin 200mg Tablet as prescribed. Your doctor will advise you on how often you need to take Dandrotin 200mg Tablet based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Dandrotin 200mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Dandrotin 200mg Tablet. Avoid breastfeeding while taking Dandrotin 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Dandrotin 200mg Tablet. Dandrotin 200mg Tablet is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

Uses of Dandrotin 200mg Tablet

Systemic fungal infections

Directions for Use

Take Dandrotin 200mg Tablet with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Dandrotin 200mg Tablet is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dandrotin 200mg Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Dandrotin 200mg Tablet. Avoid breastfeeding while taking Dandrotin 200mg Tablet as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Dandrotin 200mg Tablet. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Dandrotin 200mg Tablet:
Taking Dandrotin 200mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Dandrotin 200mg Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficult. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dandrotin 200mg Tablet:
Co-administration of Dandrotin 200mg Tablet and Isavuconazole can significantly increase the blood levels of Isavuconazole, which may increase the risk of side effects.

How to manage the interaction:
Taking Isavuconazole with Dandrotin 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Dandrotin 200mg Tablet:
Using colchicine together with Dandrotin 200mg Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Although taking Dandrotin 200mg Tablet with Colchicine is not recommended as it can cause an interaction, they can be taken if prescribed by a doctor. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without consulting a doctor
How does the drug interact with Dandrotin 200mg Tablet:
When Tolvaptan is taken with Dandrotin 200mg Tablet, may increase the risk of side effects.

How to manage the interaction:
Taking Tolvaptan with Dandrotin 200mg Tablet is not recommended as it can lead to an interaction, it can be taken if prescribed by a doctor. However, if you notice any of these signs -difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures, call a doctor right away. Do not stop using any medications without a doctor's advice.
KetoconazoleMethadone
Critical
How does the drug interact with Dandrotin 200mg Tablet:
When Methadone is taken with Dandrotin 200mg Tablet, it can increase the risk of serious side effects such as respiratory problems, low blood pressure, irregular heart rhythm.

How to manage the interaction:
Taking Dandrotin 200mg Tablet with Methadone is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience breathing difficulty, fainting, heart palpitations, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleConivaptan
Critical
How does the drug interact with Dandrotin 200mg Tablet:
Using conivaptan together with Dandrotin 200mg Tablet may significantly increase the blood levels of conivaptan, which may increase the risk of side effects.

How to manage the interaction:
Taking Dandrotin 200mg Tablet with Conivaptan is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience difficulty swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, seizures(fits), consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleTriazolam
Critical
How does the drug interact with Dandrotin 200mg Tablet:
When Triazolam is taken with Dandrotin 200mg Tablet, it can increase the risk of drowsiness and slowed breathing.

How to manage the interaction:
Taking Triazolam with Dandrotin 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dandrotin 200mg Tablet:
Co-administration of ticagrelor with Dandrotin 200mg Tablet can cause severe bleeding.

How to manage the interaction:
Taking Ticagrelor with Dandrotin 200mg Tablet is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dandrotin 200mg Tablet:
When Dronedarone is taken with Dandrotin 200mg Tablet, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Dandrotin 200mg Tablet with Dronedarone is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
How does the drug interact with Dandrotin 200mg Tablet:
Using Lurasidone together with Dandrotin 200mg Tablet may increase the risk of side effects like Parkinson's disease(It is a brain disorder that produces uncontrollable movements).

How to manage the interaction:
While lurasidone and Dandrotin 200mg Tablet is not recommended as it may lead to an interaction, they can be used if prescribed by a doctor. However, consult a doctor if you have any abnormal muscle activity, fits, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Dandrotin 200mg Tablet may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Dandrotin 200mg Tablet.

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS - ORAL

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dandrotin 200mg Tablet works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Dandrotin 200mg Tablet is not recommended to treat fungal meningitis (fungal infection spreads to the brain and spinal cord) as it poorly penetrates into the cerebrospinal fluid. Therefore, inform your doctor if you have fungal meningitis so that appropriate medication may be prescribed.

You are recommended to avoid foods containing chocolate and caffeine such as cocoa beans, tea, coffee, cola and energy drinks while taking Dandrotin 200mg Tablet as it may increase the adverse effects of caffeine such as drowsiness, nervousness or nausea.

You are not recommended to take Dandrotin 200mg Tablet with simvastatin (lipid-lowering drug) as co-administration of these medicines may cause muscle problems. Therefore, please consult a doctor before taking Dandrotin 200mg Tablet with other medicines.

No, you are not recommended to stop taking Dandrotin 200mg Tablet without consulting your doctor as it may cause recurring infection. Therefore, take Dandrotin 200mg Tablet for as long as your doctor has prescribed it and if you experience any difficulty while taking Dandrotin 200mg Tablet, please consult your doctor.

Drug-Drug Interactions Checker List

  • QUINIDINE
  • DOFETILIDE
  • PIMOZIDE
  • OMEPRAZOLE
  • CISAPRIDE
  • SIMVASTATIN
  • LOVASTATIN
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • NISOLDIPINE
  • EPLERENONE
  • ALPRAZOLAM
  • TRIAZOLAM
  • MIDAZOLAM

Disease/Condition Glossary

Systemic fungal infections are fungal infections that affect internal organs. The fungus lives in the environment, particularly in moist soil and in decomposing organic matter such as leaves and wood. Fungi enter the body via the paranasal sinuses, gut, lungs, or skin, and may spread to other organs. If these infections are not treated with appropriate therapy or if treatment is delayed, it may lead to medical emergencies. The symptoms of systemic fungal infection in people with normal immune function include cough, fever, or loss of appetite. It can also affect people who are immune compromised.

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