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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

About Esava Tablet 10's

Esava Tablet 10's belongs to a class of drugs called antifungals indicated to treat various systemic fungal infections such as blastomycosis (infection caused by Blastomyces fungus), chromomycosis (chronic infection of the skin and subcutaneous tissue), Coccidioidomycosis (infection caused by Coccidioides fungus), paracoccidioidomycosis (infection caused by Paracoccidioides fungus) and histoplasmosis (lung infection caused by Histoplasma fungus). It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks.

Esava Tablet 10's contains Ketoconazole which works by destroying fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Take Esava Tablet 10's as prescribed. Your doctor will advise you on how often you need to take Esava Tablet 10's based on your medical condition. Some people may experience headache, nausea, stomach pain, and diarrhoea. Most of these side effects of Esava Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Esava Tablet 10's. Avoid breastfeeding while taking Esava Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption whilst on treatment with Esava Tablet 10's. Esava Tablet 10's is not recommended for children below 2 years of age. For children above 2 years, it is recommended to use only if the doctor has determined that the benefits outweigh the risks.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of Esava Tablet 10's

Systemic fungal infections

Medicinal Benefits

Esava Tablet 10's is an antifungal used to treat severe fungal infections. It is used only when other effective antifungal therapies are not available or tolerated and if potential benefits outweigh potential risks. It destroys fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, kills fungi and treats the fungal infection.

Side Effects of Esava Tablet 10's

  • Headache
  • Nausea
  • Stomach pain
  • Diarrhoea 

Directions for Use

Take Esava Tablet 10's with food to avoid stomach upset or take it as advised by the doctor. Swallow the whole tablet/capsule with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Ketoconazole or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, inform your doctor before taking Esava Tablet 10's. Avoid breastfeeding while taking Esava Tablet 10's as it may be excreted in breast milk. You are recommended to avoid alcohol consumption with Esava Tablet 10's. If you have a loss of appetite, tiredness, stomach pain, vomiting, yellowing of skin or eyes, dark urine, or light-coloured stools, inform your doctor immediately as they might be symptoms of hepatotoxicity (liver damage). 

Therapeutic Class

ANTIFUNGALS - ORAL

Drug-Drug Interactions

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KetoconazoleEplerenone
Critical
KetoconazoleLovastatin
Critical

Drug-Drug Interactions

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KetoconazoleEplerenone
Critical
How does the drug interact with Esava Tablet 10's:
Coadministration of Esava Tablet 10's with Eplerenone can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Esava Tablet 10's with Eplerenone is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
KetoconazoleLovastatin
Critical
How does the drug interact with Esava Tablet 10's:
Coadministration of Lovastatin with Esava Tablet 10's can increase the risk of liver damage, rhabdomyolysis (the breakdown of skeletal muscle tissue) which may lead to kidney damage.

How to manage the interaction:
Taking Esava Tablet 10's with Lovastatin is not recommended as it can cause an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms like unexplained muscular pain, tenderness, weakness, accompanied by fever, dark urine or unexpected bruising or bleeding, skin rash, itching, vomiting, yellowing of the skin or eyes, chills, joint pain, swelling, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
KetoconazoleRegorafenib
Critical
How does the drug interact with Esava Tablet 10's:
When Regorafenib is taken with Esava Tablet 10's, it can increase the levels of Regorafenib, which may lead to side effects.

How to manage the interaction:
Taking Regorafenib with Esava Tablet 10's is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleZiprasidone
Critical
How does the drug interact with Esava Tablet 10's:
Taking Esava Tablet 10's with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone with Esava Tablet 10's is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, breathing difficult. Do not discontinue any medications without consulting a doctor.
KetoconazoleNimodipine
Critical
How does the drug interact with Esava Tablet 10's:
When Nimodipine is taken with Esava Tablet 10's, it can increase the blood levels of Nimodipine which may lead to serious side effects .

How to manage the interaction:
Taking Esava Tablet 10's with Nimodipine is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience -irregular heart rhythm, swelling, and low blood pressure, consult the doctor. Do not discontinue any medications without consulting the doctor.
KetoconazoleEliglustat
Critical
How does the drug interact with Esava Tablet 10's:
When Eliglustat is taken with Esava Tablet 10's, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Esava Tablet 10's with Eliglustat is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or slow heart rate, weak pulse, or heart palpitations, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleNaloxegol
Critical
How does the drug interact with Esava Tablet 10's:
When Naloxegol is taken with Esava Tablet 10's, it can increase the blood levels of naloxegol which may cause the side effects.

How to manage the interaction:
Taking Esava Tablet 10's with Naloxegol is not recommended as it can cause an interaction, but it can be taken if prescribe by the doctor. However, if you experience symptoms such as sweating, tearing, runny nose, chills, diarrhea, stomach pain, anxiety, difficulty sleeping, irritability, restlessness, and yawning, consult the doctor. Do not stop using any medications without talking to a doctor.
KetoconazoleHalofantrine
Critical
How does the drug interact with Esava Tablet 10's:
Using Esava Tablet 10's with Halofantrine can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Esava Tablet 10's with Halofantrine is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
KetoconazoleMidazolam
Critical
How does the drug interact with Esava Tablet 10's:
Co-administration of Esava Tablet 10's and Midazolam may increase the risk of side effects.

How to manage the interaction:
Although taking Esava Tablet 10's and Midazolam together is not recommended as it may result in an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have excessive or prolonged sleepiness and breathing issues. Do not discontinue any medication without consulting a doctor.
KetoconazoleTriazolam
Critical
How does the drug interact with Esava Tablet 10's:
When Triazolam is taken with Esava Tablet 10's, it can increase the risk of drowsiness and slowed breathing.

How to manage the interaction:
Taking Triazolam with Esava Tablet 10's is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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KETOCONAZOLE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consumption of grapefruit or its juice with Esava Tablet 10's may result in side effects such as joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, dark urine, light colored stools, and yellowing of the skin or eyes. Avoid consuming grapefruit, grapefruit juice, or any supplements that include grapefruit extract while taking Esava Tablet 10's.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • QUINIDINE
  • DOFETILIDE
  • PIMOZIDE
  • OMEPRAZOLE
  • CISAPRIDE
  • SIMVASTATIN
  • LOVASTATIN
  • DIHYDROERGOTAMINE
  • ERGOTAMINE
  • NISOLDIPINE
  • EPLERENONE
  • ALPRAZOLAM
  • TRIAZOLAM
  • MIDAZOLAM

Diet & Lifestyle Advise

  • Avoid high-risk areas such as renovated buildings, construction sites, pigeon or chick coops, and caves.
  • Wear a respiratory mask when there is a risk of exposure to spores.
  • People with a weak immune system are advised to avoid activities that involve close contact with dust or dirt including digging, yard work, and gardening.
  • Close windows and stay inside during dust storms.
  • Clean skin injuries well with soap and water to reduce the risk of developing a skin infection.

Habit Forming

No

Author Details

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Disease/Condition Glossary

Systemic fungal infections are fungal infections that affect internal organs. The fungus lives in the environment, particularly in moist soil and in decomposing organic matter such as leaves and wood. Fungi enter the body via the paranasal sinuses, gut, lungs, or skin, and may spread to other organs. If these infections are not treated with appropriate therapy or if treatment is delayed, it may lead to medical emergencies. The symptoms of systemic fungal infection in people with normal immune function include cough, fever, or loss of appetite. It can also affect people who are immune compromised.

Esava Tablet 10's Substitute

Substitutes safety advice
  • Fungicide Tablet 10's

    47.52per tablet
  • Phytoral Tablet 10's

    46.08per tablet
  • Kenz Tablet 10's

    by AYUR

    21.60per tablet
  • Hyphoral Tablet 10's

    38.03per tablet
  • Ketocip 200 mg Tablet 10's

    21.78per tablet
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