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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer :

Zuventus Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dapaformin-1000 Tab

Dapaformin-1000 Tab belongs to the class of 'antidiabetic drugs', primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. Dapaformin-1000 Tab also lowers the risk of heart failure in type 2 diabetic patients with heart diseases. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. Dapaformin-1000 Tab is not indicated for use in type 1 diabetes.

Dapaformin-1000 Tab is composed of two antidiabetic medicines, namely: Metformin and Dapagliflozin. Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine.

Take Dapaformin-1000 Tab as advised by your doctor. Some common side effects of Dapaformin-1000 Tab include nausea, vomiting, diarrhoea, headache, weakness, runny nose, genital infection, dizziness, taste changes, and sore throat. Sometimes, Dapaformin-1000 Tab can cause side effects like lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation) and diabetic ketoacidosis (excess production of blood acids (ketones)). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Dapaformin-1000 Tab may cause hypoglycaemia (low blood sugar); hence it advised to take healthy food with enough calories and avoid heavy exercises. Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Dapaformin-1000 Tab , let your doctor know if you have any medical history of heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, low blood pressure, and yeast infection of genitals. It is advised to avoid your alcohol intake while using Dapaformin-1000 Tab to decrease the risk of lactic acidosis. Dapaformin-1000 Tab is not recommended for use during the second or third trimester of pregnancy and breastfeeding.

Uses of Dapaformin-1000 Tab

Type 2 Diabetes mellitus.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it. Take it preferably with a meal since it lowers blood sugar levels and may cause gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Medicinal Benefits

Dapaformin-1000 Tab treats type 2 diabetes mellitus and contains Metformin and Dapagliflozin. Metformin is a biguanide and manages blood sugar levels, particularly in obese patients. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered a unique antidiabetic drug since it does not cause hypoglycemia (lowered blood sugar levels). Dapagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. Dapaformin-1000 Tab also reduces the risk of heart failure in patients with type 2 diabetes and heart disease. Dapaformin-1000 Tab may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Storage

Keep out of sight and reach of children.

Drug Warnings

Inform your doctor if you take other antidiabetic drugs so that the dosage of Dapaformin-1000 Tab will be adjusted accordingly. Do not abruptly stop taking Dapaformin-1000 Tab midway if the doctor did not advise you. Dapaformin-1000 Tab may cause hypoglycaemia (low blood sugar); hence it is advised to make healthy food with enough calories and avoid heavy exercises. Brief your medical history to doctor if you have any heart, kidney or liver diseases, breathing problems (asthma, obstructive lung diseases), blood problems like anaemia (lack of blood cells), vitamin B12 deficiency, pancreas problems/surgery, dehydration, alcohol use, low blood pressure, and yeast infection of genitals before taking Dapaformin-1000 Tab . Avoid alcohol intake while using Dapaformin-1000 Tab since it may increase the risk of lactic acidosis. Dapaformin-1000 Tab is not recommended for use during the second or third trimester of pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Dapaformin-1000 Tab is not recommended for people younger than 18 years of age.

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIopamidol
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Dapaformin-1000 Tab with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Dapaformin-1000 Tab with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIopamidol
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Iopamidol with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIotroxic acid
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Iotroxic acid with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIopydol
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Iopydol with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Iopydol is not recommended, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Ioversol with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Iopentol with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Dapaformin-1000 Tab and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Dapaformin-1000 Tab with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Ioglicic acid with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Iodixanol with Dapaformin-1000 Tab can increase the risk of side effects.

How to manage the interaction:
Taking Dapaformin-1000 Tab with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoxitalamic acid
Critical
How does the drug interact with Dapaformin-1000 Tab:
Co-administration of Dapaformin-1000 Tab and Ioxitalamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Dapaformin-1000 Tab with Ioxitalamic acid is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals if you take Dapaformin-1000 Tab for more than once per day. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Dapaformin-1000 Tab .
  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, avoiding carbonated drinks and foods that cause gas. 

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dapaformin-1000 Tab contains two antidiabetic medicines: Metformin and Dapagliflozin. These drugs lower the blood sugar levels in type 2 diabetes mellitus by eliminating excess sugars through urine and also by increasing the activity of insulin.

Dapaformin-1000 Tab may cause low blood sugar levels (hypoglycaemia) and can make you hungry, dizzy, irritable, confused, anxious, or shaky. Hence, it is advised to take Dapaformin-1000 Tab with a meal. To immediately treat hypoglycaemia, it is advised to eat or drink fast-acting sugar sources like fruit juices, hard candy, raisins or non-diet soda.

Your doctor may advise Dapaformin-1000 Tab with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to achieve the controlled blood sugar levels while using Dapaformin-1000 Tab with or without other antidiabetic drugs.

Dapaformin-1000 Tab should be used with caution in heart, kidney or liver diseases, breathing problems (asthma, obstructive lung disease), blood disorders (anaemia, vitamin B12 deficiency), dehydration, alcohol use, low blood pressure, pancreas problems/surgery, and yeast infection of genitals. Dapaformin-1000 Tab is contraindicated in patients with severe renal impairment and metabolic acidosis/diabetic ketoacidosis.

While using Dapaformin-1000 Tab , if you experience vomiting, stomach/abdominal pain, muscle cramps, sick feeling, severe tiredness, difficulty in breathing, or reduced body temperature and heartbeat, it is important to seek immediate medical help since these are the symptoms of lactic acidosis. Lactic acidosis is a rare but serious complication caused due to accumulation of metformin. It is a medical emergency and needs immediate treatment. Please consult your doctor for further information.

It is not recommended to use Dapaformin-1000 Tab along with water pills/diuretics. Simultaneous use of Dapaformin-1000 Tab and water pills causes dehydration and may increase the risk of lactic acidosis.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

  • HYDROCHLOROTHIAZIDE
  • IBUPROFEN
  • CELECOXIB
  • CIMETIDINE

Special Advise

  • It is advised to monitor your blood sugar levels regularly.
  • If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you stop taking Dapaformin-1000 Tab temporarily.
  • Regular monitoring of kidney functioning is advised while using Dapaformin-1000 Tab .
  • Dapaformin-1000 Tab may make you test positive for a urine glucose test, hence inform your doctor in advance that you take Dapaformin-1000 Tab . 

Disease/Condition Glossary

Diabetes mellitus, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots. 

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