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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Whats That

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Composition :

DARUNAVIR-600MG

Manufacturer/Marketer :

Cipla Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Daruvir 600mg Tablet

Daruvir 600mg Tablet belongs to a class of antiretroviral drugs called protease inhibitors primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children aged 3 years and above weighing at least 15kg. HIV is a virus that targets the immune system, primarily white blood cells. HIV destroys white blood cells and reduces a person's resistance to infections.

Daruvir 600mg Tablet contains Darunavir that works by inhibiting a protein called protease, which is required by virus-infected cells to generate new viruses. As a result, Daruvir 600mg Tablet reduces the amount of HIV in the body. Thereby, helps improve the immune system and lowers the risk of developing any illness related to HIV infection.

Take Daruvir 600mg Tablet with food. Your doctor will decide the dose and duration based on your medical condition. In some cases, Daruvir 600mg Tablet may cause certain common side effects such as headache, nausea, dizziness, abdominal pain, diarrhoea, and vomiting. Most of these side effects do not necessitate medical treatment and fade away with time. Please check with your doctor if the side effects persist or worsen.

Consult your doctor before taking Daruvir 600mg Tablet if you are pregnant. Due to the risk of HIV transmission, women infected with HIV are recommended not to breastfeed. Daruvir 600mg Tablet may cause dizziness, so drive only if you are alert. Daruvir 600mg Tablet should not be given to children below 3 years of age or weighing below 15kg as safety and effectiveness have not been established. Avoid or limit alcohol consumption as it may cause increased dizziness. Keep your doctor updated about your health condition and medications to rule out any interactions.

Uses of Daruvir 600mg Tablet

HIV (human immunodeficiency virus) infection.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Daruvir 600mg Tablet falls under the category of antiretroviral agents. It is primarily used to treat HIV (Human Immunodeficiency Virus) infection in adults and children aged 3 years and above weighing at least 15kg. Daruvir 600mg Tablet works by inhibiting a protein enzyme called protease, which is required by virus-infected cells to generate new viruses. As a result, Daruvir 600mg Tablet reduces the amount of HIV in the body. Thereby, helps improve the immune system and lowers the risk of developing any illness related to HIV infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Daruvir 600mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Drug Warnings

Please do not take Daruvir 600mg Tablet if you are allergic to any of its constituents or if you have severe liver problems. Inform your doctor if you have diabetes, infections, haemophilia, musculoskeletal problems, rash, kidney or liver impairment. Consult your doctor before taking Daruvir 600mg Tablet if you are pregnant. Due to the risk of HIV transmission, women infected with HIV are recommended not to breastfeed. Daruvir 600mg Tablet may cause dizziness, so drive only if you are alert. Daruvir 600mg Tablet should not be given to children below 3 years of age or weighing below 15kg as safety and effectiveness have not been established. Avoid or limit alcohol consumption as it may cause increased dizziness. While taking this medication, you can still pass on HIV, though the risk is reduced by effective antiretroviral therapy. Discuss with your doctor the precautions you should take to avoid infecting others. Talk to your doctor immediately if you notice any signs or symptoms of infection or inflammation. Keep your doctor updated on your health condition and medications to rule out any negative effects or adverse events.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Daruvir 600mg Tablet:
Coadministration of colchicine with Daruvir 600mg Tablet may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Daruvir 600mg Tablet is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Daruvir 600mg Tablet:
Taking Daruvir 600mg Tablet with rifampicin can decrease the blood levels of Daruvir 600mg Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Daruvir 600mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Daruvir 600mg Tablet:
Using Lurasidone together with Daruvir 600mg Tablet may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
While Lurasidone and Daruvir 600mg Tablet may interact, they can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Daruvir 600mg Tablet:
Combining Daruvir 600mg Tablet and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis( involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Daruvir 600mg Tablet and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Daruvir 600mg Tablet:
Combining Daruvir 600mg Tablet and Sildenafil can increase the blood levels and effects of Sildenafil.

How to manage the interaction:
Taking Daruvir 600mg Tablet and Sildenafil together is avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, shortness of breath, dizziness, lightheadedness, fainting, visual disturbances, ringing in the ears, vision or hearing loss, chest pain or tightness, irregular heartbeat, and/or priapism (prolonged and painful erection unrelated to sexual activity), contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Daruvir 600mg Tablet:
Taking bosutinib with Daruvir 600mg Tablet can considerably increase blood levels of bosutinib, increasing the risk of side effects.

How to manage the interaction:
Although there is an interaction between Bosutinib and Daruvir 600mg Tablet, it can be taken if your doctor has suggested it. they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, burning during urination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Daruvir 600mg Tablet:
When Bromocriptine is taken with Daruvir 600mg Tablet, the amount of Bromocriptine in the blood can increase.

How to manage the interaction:
There may be a possibility of interaction between Daruvir 600mg Tablet and Bromocriptine, but it can be taken if prescribed by a doctor. Consult your doctor immediately if you have any symptoms - headache, dizziness, sleepiness, or lightheadedness. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Daruvir 600mg Tablet:
Coadministration of Phenytoin and Daruvir 600mg Tablet may decrease the blood levels of Daruvir 600mg Tablet, which may make Daruvir 600mg Tablet less effective.

How to manage the interaction:
Although taking Phenytoin and Daruvir 600mg Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.
How does the drug interact with Daruvir 600mg Tablet:
Using Daruvir 600mg Tablet and olaparib can increase the blood levels of olaparib. This can increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, indigestion, loss of appetite, abdominal pain or discomfort, lung problems, and impaired bone marrow function resulting in low numbers of different types of blood cells.

How to manage the interaction:
Combining Daruvir 600mg Tablet and olaparib can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact the doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Daruvir 600mg Tablet:
Taking Everolimus with Daruvir 600mg Tablet can considerably raise blood levels of everolimus, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although there is a possible interaction between Daruvir 600mg Tablet and Everolimus, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take care of your mental health. Fear and anxiety can hamper the immune system as well. Therapy, yoga, and meditation effectively provide peace of mind.
  • Spending time with family or doing whatever makes you happy might help minimise emotional and physical stress.
  • Never exchange personal objects that have been contaminated with bodily fluids or blood, such as razor blades or toothbrushes.
  • Never share used needles, other injection or drug equipment as it may spread viruses.
  • Use condoms for safe sex; it helps to reduce contact with sperm and vaginal fluids.
  • Other sexually transmitted infections, such as gonorrhoea or syphilis, can make you more susceptible to HIV infection.
  • Consume a well-balanced diet. Include vitamin and nutrient-rich foods like dark-green, yellow, orange, red vegetables and fruits to enhance your immune system. Choose lean protein and whole carbohydrates over-processed foods.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Daruvir 600mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Daruvir 600mg Tablet works by inhibiting protease enzyme that is essential for the reproduction of the human immunodeficiency virus. Thereby, it prevents the production of the new human immunodeficiency virus. Thus, Daruvir 600mg Tablet lowers virus load in the body and helps treat the infection.

Some patients taking antiretroviral combination therapy may develop osteonecrosis (death of bone tissue due to loss of blood supply to the bone). If you experience joint ache, pain, stiffness, or difficulty movement, consult your doctor.

In some cases, Daruvir 600mg Tablet may cause a rash, especially when used in combination with raltegravir. A rash is generally mild to moderate. However, occasionally it may become severe. Please inform your doctor if you develop a rash.

Daruvir 600mg Tablet might increase sugar levels in the blood, therefore, consult your doctor before taking Daruvir 600mg Tablet if you are diabetic. You are advised to monitor your blood glucose levels regularly while taking Daruvir 600mg Tablet .

Do not stop taking Daruvir 600mg Tablet without consulting your doctor as it may reduce the effectiveness of anti-HIV therapy. Continue taking Daruvir 600mg Tablet for as long as your doctor has prescribed it to you to treat your condition effectually. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Daruvir 600mg Tablet .

Drug-Drug Interactions Checker List

  • EMTRICITABINE
  • TENOFOVIR ALAFENAMIDE
  • ETRAVIRINE
  • DILTIAZEM
  • AVANAFIL
  • ASTEMIZOLE
  • TERFENADINE
  • TRIAZOLAM
  • MIDAZOLAM
  • CISAPRIDE
  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • ERGOMETRINE
  • QUINIDINE
  • RANOLAZINE
  • AMIODARONE
  • SILDENAFIL
  • DABIGATRAN
  • TICAGRELOR
  • ST JOHN'S WORT

Special Advise

  • Monitoring liver function before and during medication, especially in individuals with underlying chronic hepatitis, or cirrhosis.
  • Glucose levels should be monitored. During post-marketing surveillance, hyperglycemia has been found in HIV-infected patients receiving protease inhibitor medication.
  • It is essential that you do not miss or skip any doses while on treatment. If you miss a dosage of Daruvir 600mg Tablet , take it as soon as you remember. However, if it is time for the next scheduled dose, skip the missed dose and take the scheduled dose. Avoid double dosing.

Disease/Condition Glossary

HIV infection: HIV (human immunodeficiency virus) is a virus that damages immune system cells and impairs your ability to fight infections and diseases. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure. However, it can be controlled by treatment with antiretroviral drugs. 

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