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Written By Divya L , PharmaD
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About DECOLIC AMPULE 2ML

DECOLIC AMPULE 2ML belongs to the class of ‘antispasmodic/anticholinergic/anti-muscarinic agents,’ primarily used to treat functional bowel or irritable bowel syndrome (IBS). DECOLIC AMPULE 2ML reduces spasms (sudden involuntary contraction) of the muscles in the stomach and intestines. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhoea.

DECOLIC AMPULE 2ML contains ‘Dicyclomine,’ also known as Dicycloverine. Dicyclomine belongs to the class of ‘anticholinergic/anti-muscarinic agents’ with antispasmodic activity. DECOLIC AMPULE 2ML blocks the activity of acetylcholine (acetylcholine is a neurotransmitter that sends signals to nerve cells) by binding to muscarinic receptors on smooth muscle. This process helps relax smooth muscles and inhibits natural gut movements. Thus it prevents spasms in the muscles of the stomach and intestine.

DECOLIC AMPULE 2ML will be administered by a healthcare professional. Your doctor will advise the appropriate dose based on your medical condition. It shows common side effects like dizziness, drowsiness, light-headedness, weakness, nervousness, blurred vision, dry mouth, nausea, constipation, and trouble sleeping. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please consult your doctor.

Let your doctor know if you are allergic to any medications. Inform your doctor if you have liver, kidney, heart disease, or other medical histories before receiving DECOLIC AMPULE 2ML. Some antacids may inhibit the absorption of DECOLIC AMPULE 2ML; hence maintain a time gap between the intake of antacids and DECOLIC AMPULE 2ML. DECOLIC AMPULE 2ML may cause blurred vision, dizziness and drowsiness; hence do not drive or operate machinery until you feel better. Let your doctor know if you are pregnant and breastfeeding before taking DECOLIC AMPULE 2ML. This medicine is not recommended for children below six months of age.

Uses of DECOLIC AMPULE 2ML

Irritable bowel syndrome (IBS). 

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

DECOLIC AMPULE 2ML contains ‘Dicyclomine,’ also known as Dicycloverine. Dicyclomine is an ‘anticholinergic/anti-muscarinic agent’ with antispasmodic activity. DECOLIC AMPULE 2ML effectively treats irritable bowel syndrome (IBS). It works by blocking the activity of acetylcholine by binding to muscarinic receptors on smooth muscle. This process helps relax the smooth muscles, inhibits natural gut movements, decreases gastric acid secretion, and controls excessive gastrointestinal secretions. Thus it prevents spasms in the muscles of the stomach and intestines. DECOLIC AMPULE 2ML is also used to relieve stomach cramps, bloating, and pain in the stomach and intestine.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DECOLIC AMPULE 2ML

  • Dizziness
  • Drowsiness
  • Light-headedness
  • Weakness
  • Nervousness
  • Blurred vision
  • Dry mouth
  • Nausea
  • Constipation
  • Trouble sleeping 

Drug Warnings

Let your doctor know if you are sensitive to DECOLIC AMPULE 2ML or its inactive components. DECOLIC AMPULE 2ML should be used with caution and only under doctor’s supervision if you have stomach/intestinal problems like slow gut, bowel blockage, acid reflux, ulcerative colitis (inflammation of the colon), and diarrhoea due to intestine surgeries like ileostomy and colostomy. Also, inform your doctor if you have any liver or kidney diseases, urinary retention problems (enlarged prostate), glaucoma, high blood pressure, heart diseases (irregular heart rhythm, coronary artery disease, heart failure), nervous system disorders, and myasthenia gravis (muscle weakness) before using DECOLIC AMPULE 2ML. This medicine may cause blurry vision and sleepiness affecting your mental focus; hence do not drive or operate machinery until you feel better. Tell your doctor if you are pregnant, planning pregnancy, or a nursing mother before being treated with DECOLIC AMPULE 2ML.

Drug-Drug Interactions

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DicyclominePramlintide
Critical
DicyclominePotassium citrate
Critical

Drug-Drug Interactions

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DicyclominePramlintide
Critical
How does the drug interact with Decolic Ampule 2ml:
Co-administration of Pramlintide with Decolic Ampule 2ml can increase the risk of reduced gastrointestinal movement.

How to manage the interaction:
Taking Decolic Ampule 2ml with Pramlintide is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
DicyclominePotassium citrate
Critical
How does the drug interact with Decolic Ampule 2ml:
Taking Decolic Ampule 2ml and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Decolic Ampule 2ml with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DicyclominePotassium chloride
Critical
How does the drug interact with Decolic Ampule 2ml:
Co-administration of Decolic Ampule 2ml with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Decolic Ampule 2ml with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
DicyclomineSecretin
Severe
How does the drug interact with Decolic Ampule 2ml:
Co-administration of Secretin human with Decolic Ampule 2ml may decrease the therapeutic efficacy of Secretin human.

How to manage the interaction:
Taking Decolic Ampule 2ml with Secretin together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
DicyclomineZonisamide
Severe
How does the drug interact with Decolic Ampule 2ml:
Co-administration of Decolic Ampule 2ml with Zonisamide may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Decolic Ampule 2ml and Zonisamide together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue any medication without consulting a doctor.
DicyclomineTopiramate
Severe
How does the drug interact with Decolic Ampule 2ml:
Co-administration of Decolic Ampule 2ml with Topiramate may worsen effects like increased body temperature and sweating.

How to manage the interaction:
If you have to use Decolic Ampule 2ml and Topiramate together, your doctor may adjust the dose or monitor you more frequently to safely use both medications. Drink plenty of fluids during warm weather and when exercising and contact a doctor if you have decreased sweating or a fever. You may also experience drowsiness, dizziness, or lightheadedness when taking these medications together. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid or limit the intake of alcohol and caffeine.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Limit taking high-fibre foods and drinks containing chocolate, milk, alcohol, caffeine, fructose, sorbitol, carbonated drinks, fried, and fatty foods. 
  • Do not have large meals at a time; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables.
  • Practice yoga and recreation techniques to manage your emotional stress.
  • If you are lactose intolerant, avoid using dairy products since they can worsen your IBS.
  • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
  • Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.
  • Avoid overly sweating activities like hard exercises and using hot tubs.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS

DECOLIC AMPULE 2ML Substitute

Substitutes safety advice
  • Meftal Spas Injection 2 ml

    by Others

    3.15per tablet

Author Details

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Drug-Diseases Interactions

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DICYCLOMINE-10MGOther disorders of nervous system in diseases classified elsewhere
Severe
DICYCLOMINE-10MGParalytic ileus and intestinal obstruction without hernia
Severe

Drug-Diseases Interactions

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DICYCLOMINE-10MGOther disorders of nervous system in diseases classified elsewhere
Severe
How does the disease interact with Decolic Ampule 2ml:
Anticholinergic substances can make several autonomic neuropathy symptoms worse, such as tachycardia, anhidrosis, and male sexual impotence. In individuals with autonomic neuropathy, antimuscarinic therapy and stronger antispasmodic dosages should be used with caution.

How to manage the interaction:
Higher dosages of Decolic Ampule 2ml should be used with caution in patients with autonomic neuropathy (damage to the nerves that control automatic body functions).
DICYCLOMINE-10MGParalytic ileus and intestinal obstruction without hernia
Severe
How does the disease interact with Decolic Ampule 2ml:
Anticholinergic medications should not be used in people with obstructive illnesses such achalasia. Anticholinergics may further reduce intestinal motility, causing a toxic megacolon to develop or worsen as a result.

How to manage the interaction:
Decolic Ampule 2ml is contraindicated in patients with obstructive diseases such as achalasia (difficulty in passing food and liquid into the stomach), oesophagal stricture or stenosis (abnormal tightening or narrowing of the food pipe), pyloroduodenal stenosis (narrowing of the opening from the stomach to the first part of the small intestine called pylorus), stenosing peptic ulcer, pyloric obstruction, and paralytic ileus (muscle contractions that move food through your intestines are temporarily paralyzed).
DICYCLOMINE-10MGGlaucoma
Severe
How does the disease interact with Decolic Ampule 2ml:
Patients with primary glaucoma, a propensity for glaucoma, or adhesions between the iris and lens, as well as the elderly and other people who may have undiagnosed glaucoma or high eye pressure, should not use anticholinergic medications. Anticholinergics may make these problems worse because they produce mydriasis.

How to manage the interaction:
Decolic Ampule 2ml is contraindicated in patients with primary glaucoma, a tendency toward glaucoma (narrow anterior chamber angle), or adhesions (synechiae) between the iris and lens, as well as for the elderly and others in whom undiagnosed glaucoma or excessive pressure in the eye may be present as this medicine may worsen these conditions.
DICYCLOMINE-10MGNeuromuscular dysfunction of bladder, not elsewhere classified
Severe
How does the disease interact with Decolic Ampule 2ml:
Patients with urine retention and bladder neck obstruction brought on by prostatic hypertrophy should not take anticholinergic medications. Dysuria is a possibility that might call for catheterization. Anticholinergic medications may also make partial obstructive uropathy worse.

How to manage the interaction:
Use of anticholinergic agents such as Decolic Ampule 2ml is contraindicated in patients with urinary retention and bladder-neck obstruction caused by prostatic hypertrophy (enlarged prostate gland).
DICYCLOMINE-10MGMyasthenia gravis and other myoneural disorders
Severe
How does the disease interact with Decolic Ampule 2ml:
Antimuscarinic medications are not advised for use in people with myasthenia gravis since they have anticholinergic effects. It may be suitable to use them to lessen the negative muscarinic effects brought on by an anticholinesterase drug.

How to manage the interaction:
Decolic Ampule 2ml is contraindicated in patients with myasthenia gravis (skeletal muscle weakness).
DICYCLOMINE-10MGCerebral infarction
Severe
How does the disease interact with Decolic Ampule 2ml:
Patients who have an acute bleeding and an unstable circulatory condition should not receive Decolic Ampule 2ml therapy.

How to manage the interaction:
Decolic Ampule 2ml therapy is not recommended for patients who have acute bleeding and an unstable circulatory condition.
DICYCLOMINE-10MGDystonia
Moderate
How does the disease interact with Decolic Ampule 2ml:
Tardive dyskinesia can be made worse by anticholinergic medications and medications with secondary anticholinergic effect. If symptoms of tardive dyskinesia appear or get worse while you are on an anticholinergic medication, stopping the medication right away will increase your chances of curing the illness.

How to manage the interaction:
Decolic Ampule 2ml should be used with caution in patients with preexisting tardive dyskinesia (involuntary repetitive body movements), particularly in the elderly. If tardive dyskinesia symptoms develop or worsen during treatment with this medicine, stopping the medication will provide better chance of improving the condition.

Drug-Drug Interactions Checker List

  • AMANTADINE
  • QUINIDINE
  • MEPERIDINE
  • METOCLOPRAMIDE
  • DIPHENHYDRAMINE
  • CYCLOBENZAPRINE
  • METOPROLOL

Disease/Condition Glossary

Irritable Bowel Syndrome (IBS): IBS is also known as IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhoea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches. IBS can be controlled by managing diet, excluding certain intolerant foods, lifestyle and stress. It is commonly found in people in their late teens to early 40s. 

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