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  3. Denopsy 14 mg Tablet 10's

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Composition :

TERIFLUNOMIDE-14MG

Manufacturer/Marketer :

Natco Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Denopsy 14 mg Tablet

Denopsy 14 mg Tablet belongs to the class of medicines called immunomodulatory agents indicated in the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Multiple sclerosis is a condition in which nerves do not function properly.
 
Denopsy 14 mg Tablet contains Teriflunomide, which works by decreasing inflammation and the action of immune cells that cause nerve damage. Thus, it helps treat multiple sclerosis.
 
In some cases, Denopsy 14 mg Tablet may cause side effects such as headache, nausea, diarrhoea, and hair loss. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to consult the doctor if the side effects persist or worsen.
 
Do not take Denopsy 14 mg Tablet if you are pregnant or breastfeeding. Denopsy 14 mg Tablet is not recommended for children as safety and effectiveness have not been established. Inform the doctor about the medicines you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Denopsy 14 mg Tablet

Multiple sclerosis

Directions for Use

Take the medicine as advised by the doctor. Treatment will be overseen by a doctor who is experienced in the treatment of multiple sclerosis.

Medicinal Benefits

Denopsy 14 mg Tablet belongs to the class of medicines called immunomodulatory agents indicated in the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. Denopsy 14 mg Tablet contains Teriflunomide, which works by protecting the central nervous system against attacks by the immune system by limiting the increase of lymphocytes (white blood cells). This helps limit the inflammation that leads to nerve damage in multiple sclerosis.

Storage

Keep Denopsy 14 mg Tablet out of reach and sight of children.
Side effects of Denopsy 14 mg Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Weight loss without physical activity needs immediate medical attention.
  • Get a physical examination and blood tests done to identify factors causing weight loss that could be related to metabolism and thyroid function.
  • Avoid smoking and alcohol intake as it can alter your liver condition and increase your weight loss.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of weight loss.
  • Talk to your dietician and consume food which can maintain ideal weight.

Drug Warnings

Do not take Denopsy 14 mg Tablet if you are allergic to any of its components, teriflunomide or leflunomide; if you have severe liver disease, any serious condition that affects the immune system, bone marrow problems, low blood count, serious infection, serious kidney problem which requires dialysis, or hypoproteinaemia (low levels of protein). Inform the doctor if you have liver problems, high blood pressure, infection, diabetes, breathing problems, severe skin reactions, respiratory symptoms, tuberculosis, or peripheral neuropathy. Do not take Denopsy 14 mg Tablet if you are pregnant or breastfeeding. Consult the doctor immediately if you become pregnant during treatment with Denopsy 14 mg Tablet . This medicine may cause serious or life-threatening liver damage that may require a liver transplant. The risk of liver damage may be increased in people taking other medications known to cause liver damage and in people who already have liver disease. Seek medical attention if you experience symptoms of liver problems such as nausea, vomiting, unusual bleeding or bruising, extreme tiredness, lack of energy, pain in the upper right part of the stomach, loss of appetite, yellowing of the skin or eyes, dark-coloured urine, or flu-like symptoms. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Denopsy 14 mg Tablet:
Co- administration of Fenofibrate with Denopsy 14 mg Tablet can cause liver issues and taking it with other medications that might harm the liver, such as fenofibrate, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Denopsy 14 mg Tablet and Fenofibrate, but it can be taken if prescribed by a doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Denopsy 14 mg Tablet:
Using Mitoxantrone together with Denopsy 14 mg Tablet may increase the risk of serious infections.

How to manage the interaction:
Although taking Mitoxantrone and Denopsy 14 mg Tablet together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, sore throat, muscle aches, shortness of breath, weight loss, discomfort, and pain or burning during urination. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Denopsy 14 mg Tablet:
Taking Idarubicin and Denopsy 14 mg Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, Idarubicin can be taken with Denopsy 14 mg Tablet, if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Denopsy 14 mg Tablet:
Coadministration of Acitretin with Denopsy 14 mg Tablet may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Acitretin and Denopsy 14 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Denopsy 14 mg Tablet:
Coadministration of Denopsy 14 mg Tablet and bosentan may increase the risk of liver problems.

How to manage the interaction:
Although taking Bosentan with Denopsy 14 mg Tablet can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, if you experience any symptoms such as joint pain, unusual bleeding, skin rash, itching, tiredness, dark urine, light stools, and/or yellowing of the skin or eyes, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Denopsy 14 mg Tablet:
When Efavirenz is taken with Denopsy 14 mg Tablet, the risk and severity of developing liver problems increases

How to manage the interaction:
There may be a possibility of interaction between Efavirenz and Denopsy 14 mg Tablet, but it can be taken if prescribed by a doctor. If you have any of these symptoms like fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, liver damage, or bleeding, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Denopsy 14 mg Tablet:
Co-administration of Denopsy 14 mg Tablet and sodium valproate can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Denopsy 14 mg Tablet and sodium valproate can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Denopsy 14 mg Tablet:
When Azathioprine is taken with Denopsy 14 mg Tablet, may raise the risk of side effects affecting bone marrow function, resulting in low levels of different types of blood cells. This can increase your chances of developing anemia, bleeding issues, or infections.

How to manage the interaction:
Taking Azathioprine with Denopsy 14 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience paleness, exhaustion, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, or pain or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Denopsy 14 mg Tablet:
Taking Denopsy 14 mg Tablet with ethionamide can increase the risk of liver problems.

How to manage the interaction:
Taking Ethionamide with Denopsy 14 mg Tablet together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms - fever, joint pain, swelling, skin rash, vomiting, abdominal pain, dark-coloured urine - immediately contact your doctor. Do not stop using any medications without talking to your doctor.
How does the drug interact with Denopsy 14 mg Tablet:
The use of asparaginase in conjunction with Denopsy 14 mg Tablet may raise the risk of severe infections, liver problems.

How to manage the interaction:
Co-administration of Asparaginase with Denopsy 14 mg Tablet can result in an interaction, but it can be taken if a doctor has advised it. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid heavily processed foods and saturated fats.
  • Include fruits, vegetables, and whole grains in the diet.
  • Try to stay active. Choose moderate exercises.
  • Quit smoking.
  • Prevent stress by doing meditation or yoga.

Habit Forming

No

Therapeutic Class

IMMUNOMODULATORS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Denopsy 14 mg Tablet works by decreasing inflammation and the action of immune cells that cause nerve damage.

Denopsy 14 mg Tablet may cause inflammation of the pancreas. Consult the doctor if you experience nausea, vomiting or pain in the abdomen.

Avoid undergoing any vaccination while on treatment with Denopsy 14 mg Tablet and for six months after taking the last dose of it. Talk to the doctor if you are due to undergo any vaccinations.

Denopsy 14 mg Tablet may increase blood pressure. Your doctor may monitor blood pressure levels before and during the treatment.

Drug-Drug Interactions Checker List

  • ETHINYLESTRADIOL
  • LEVONORGESTREL
  • WARFARIN
  • ROSUVASTATIN

Special Advise

  • Avoid undergoing any vaccination while on treatment with Denopsy 14 mg Tablet and for six months after you stop taking it.
  • You must not begin taking Denopsy 14 mg Tablet until you have taken a pregnancy test with negative results and your doctor tells you that you are not pregnant.
  • Women should use effective contraception during treatment with Denopsy 14 mg Tablet and for up to 2 years after the last dose.
  • Men with partners of reproductive potential must use reliable methods of contraception during treatment with Denopsy 14 mg Tablet .
  • Regular liver function tests are advised.

Disease/Condition Glossary

Multiple sclerosis: It is an autoimmune disease (the body attacks itself by mistake) that affects the central nervous system (brain and spinal cord). The immune system damages the myelin sheath (protective covering surrounding the nerve cells), leading to disrupted communication between the brain and the body. People suffering from multiple sclerosis may experience loss of muscle coordination, numbness, weakness, and problems with bladder control, vision, and speech.

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