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  3. Dicorate ER 500 Tablet 10's

Dicorate ER 500 Tablet 10's, Pack of 10 TABLETS
Dicorate ER 500 Tablet 10's, Pack of 10 TABLETS
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
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Whats That

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Composition :

DIVALPROEX SODIUM-500MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dicorate ER 500 Tablet

Dicorate ER 500 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Dicorate ER 500 Tablet is also used to treat manic episodes associated with bipolar disorder and to prevent migraine. Epilepsy is a sudden rush of electricity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures.

Dicorate ER 500 Tablet contains 'Divalproex sodium', which decreases the brain's excessive and abnormal nerve activity. Thereby helps in controlling seizures. Dicorate ER 500 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 

Take Dicorate ER 500 Tablet with or without food. You are advised to take Dicorate ER 500 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as abdominal pain, back pain, constipation, diarrhoea, dizziness, nausea, increased appetite, and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Please do not stop taking Dicorate ER 500 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Dicorate ER 500 Tablet if you are pregnant as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Dicorate ER 500 Tablet . Consult your doctor before taking Dicorate ER 500 Tablet if you are breastfeeding. Avoid driving or operating machinery as Dicorate ER 500 Tablet causes dizziness, and may affect thinking and motor skills. Avoid consuming alcohol along with Dicorate ER 500 Tablet as it could lead to increased dizziness. Care should be taken while giving Dicorate ER 500 Tablet to children below 2years as there is a higher risk of liver intoxication during the first 6months of treatment. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Dicorate ER 500 Tablet

Epilepsy, bipolar disorder, migraine

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew, or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.Sprinkle capsule: Swallow it as a whole with water or sprinkle the capsule contents on food and consume.

Medicinal Benefits

Dicorate ER 500 Tablet belongs to a group of medicines called anticonvulsants or anti-epileptics. Dicorate ER 500 Tablet is used to treat epilepsy/seizures/fits. Additionally, Dicorate ER 500 Tablet is also used to treat mood disorder and to prevent migraine headaches. Dicorate ER 500 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Dicorate ER 500 Tablet treats mood disorder by increasing the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect. Dicorate ER 500 Tablet prevents migraine headache by limiting the transmission of nerve pain. Dicorate ER 500 Tablet is used alone or in combination to treat simple seizures, complex partial seizures and complex absence seizures. Dicorate ER 500 Tablet is used in combination to treat multiple seizures such as absence seizures.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dicorate ER 500 Tablet
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.
  • Polycystic ovary syndrome is a commonly occurring health condition that needs to be corrected.
  • Maintain a diet rich in omega fatty acids like fish, nuts and plant oils.
  • Exercise to maintain a healthy weight within BMI to improve your condition.
  • Make sure to get sufficient sleep and avoid stress, which could increase the side effects of PCOD.
  • Smoking and drinking alcohol can worsen PCOD; therefore, avoid them.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
  • Hallucination is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control hallucinations. You can share what is being seen with a therapist to know whether they are real or imaginary.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your imagination.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes of hallucinations.
  • Talk to your dietician and consume food that can improve your mental health.

Drug Warnings

Do not take Dicorate ER 500 Tablet if you are allergic to any of its contents, have/ had liver problems or urea cycle disorders. Inform your doctor before taking Dicorate ER 500 Tablet if you have pancreatitis, blood problems or multi-organ hypersensitivity. Consult your doctor immediately if you experience suicidal tendency while taking Dicorate ER 500 Tablet . Dicorate ER 500 Tablet may cause thrombocytopenia (low blood platelets), hyperammonemia (high levels of ammonia in the blood), hypothermia (low body temperature) and liver problems. Please do not stop taking Dicorate ER 500 Tablet without consulting your doctor to avoid worsening of seizures. Do not take Dicorate ER 500 Tablet if you are pregnant as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Dicorate ER 500 Tablet . Consult your doctor before taking Dicorate ER 500 Tablet if you are breastfeeding. Avoid driving or operating machinery as Dicorate ER 500 Tablet causes dizziness and may affect thinking and motor skills. Avoid consuming alcohol along with Dicorate ER 500 Tablet as it could lead to increased dizziness. Care should be taken while giving Dicorate ER 500 Tablet to children below 2years as there is a higher risk of liver intoxication during the first 6months of treatment.

Drug-Drug Interactions

verifiedApollotooltip
Sodium ValproateSodium phenylbutyrate
Critical
Sodium ValproateErtapenem
Severe

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Dicorate ER 500 Tablet:
Combining Sodium phenylbutyrate and Dicorate ER 500 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Dicorate ER 500 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateErtapenem
Severe
How does the drug interact with Dicorate ER 500 Tablet:
The combined use of Ertapenem and Dicorate ER 500 Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Dicorate ER 500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
Sodium ValproateKetamine
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Ketamine and Dicorate ER 500 Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Dicorate ER 500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
Sodium ValproateDoripenem
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Dicorate ER 500 Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Dicorate ER 500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateBuprenorphine
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Using buprenorphine together with Dicorate ER 500 Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Dicorate ER 500 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLeflunomide
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Leflunomide and Dicorate ER 500 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Dicorate ER 500 Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateLithium
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Lithium with Dicorate ER 500 Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Dicorate ER 500 Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
Sodium ValproateVorinostat
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Vorinostat with Dicorate ER 500 Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Dicorate ER 500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
Sodium ValproateMeropenem
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Meropenam and Dicorate ER 500 Tablet together can reduce the effect of Dicorate ER 500 Tablet.

How to manage the interaction:
Co-administration of Meropenam and Dicorate ER 500 Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Sodium ValproateTeriflunomide
Severe
How does the drug interact with Dicorate ER 500 Tablet:
Co-administration of Teriflunomide and Dicorate ER 500 Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Dicorate ER 500 Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fay and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower the stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan, help those around you know what to do.
  • Prepare your living area, small changes may reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:33 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dicorate ER 500 Tablet decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures.

Dicorate ER 500 Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Dicorate ER 500 Tablet limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.

Do not discontinue Dicorate ER 500 Tablet without consulting your doctor. To treat your condition effectually continue taking Dicorate ER 500 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Dicorate ER 500 Tablet , your doctor will reduce the dose gradually to avoid worsening of seizures.

Dicorate ER 500 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Use an effective method of contraception during the treatment with Dicorate ER 500 Tablet . Avoid getting pregnant while taking Dicorate ER 500 Tablet as it could lead to serious birth defects. Do not stop taking Dicorate ER 500 Tablet and consult your doctor immediately if you become pregnant.

Dicorate ER 500 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising. Regular monitoring of blood count is advised while taking Dicorate ER 500 Tablet .

Topiramate (anticonvulsant) should not be taken along with Dicorate ER 500 Tablet as it may cause hyperammonemia (excess ammonia in the blood), hypothermia (low body temperature) and liver problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PREGABALIN
  • TOPIRAMATE
  • PHENOBARBITAL
  • PRIMIDONE
  • PHENYTOIN
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ETHOSUXIMIDE
  • ZIDOVUDINE
  • DULOXETINE
  • ESCITALOPRAM
  • AMITRIPTYLINE
  • NORTRIPTYLINE
  • ARIPIPRAZOLE
  • LURASIDONE
  • QUETIAPINE
  • ALPRAZOLAM
  • RIFAMPICIN
  • WARFARIN
  • IMIPENEM
  • MEROPENEM
  • DIAZEPAM

Special Advise

  • Regular monitoring of blood count and coagulation tests are advised while taking Dicorate ER 500 Tablet as it may cause thrombocytopenia (low platelet levels).
  • Dicorate ER 500 Tablet may cause liver toxicity, usually during the first 6months of treatment. Children below two years are at a higher risk. Regular monitoring of liver function tests before treatment and at frequent intervals is advised.
  • Dicorate ER 500 Tablet might alter thyroid function tests and urine ketone tests. Inform the person doing the tests that you are taking Dicorate ER 500 Tablet .

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulse that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalised and partial seizures. Generalised seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Mood disorder: It is a mental health disorder which mainly affects a person's emotional state. A mood disorder is associated with episodes of mood swings ranging from manic highs to depressive lows.

Migraine: Migraine is a neurological condition which is characterized by intense headaches. Symptoms include nausea, vomiting, and sensitivity to light and sound.

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