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  3. Dilantin Oral Suspension 100 ml

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Composition :

PHENYTOIN-125MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dilantin Oral Suspension

Dilantin Oral Suspension belongs to the group of medicines called 'anticonvulsants' used to treat epilepsy/seizures, and prevent seizures during/after brain surgery or after traumatic brain injury. Besides this, Dilantin Oral Suspension may also be used to treat trigeminal neuralgia (facial nerve pain). Epilepsy is a central nervous system disorder characterized by a sudden rush of electrical activity in the brain leading to seizures, unusual behaviour, and loss of awareness.

Dilantin Oral Suspension contains 'Phenytoin' which helps prevent neurons from working at a very fast speed, thereby preventing the brain cells from firing together rapidly in an uncontrolled way. As a result, Dilantin Oral Suspension controls the overactivity of the brain cells that causes seizures. Dilantin Oral Suspension slows down the electrical impulses in the nerves and reduces their ability to transmit pain. Thereby treats trigeminal neuralgia.

Take Dilantin Oral Suspension with or without food. You are advised to take Dilantin Oral Suspension for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Dilantin Oral Suspension may cause certain common side-effects such as weakness, drowsiness, dizziness, restlessness, and constipation. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Dilantin Oral Suspension for as long as your doctor has prescribed it. Please do not skip any doses or stop taking Dilantin Oral Suspension suddenly without consulting your doctor as it may lead to increased seizures. Avoid taking Dilantin Oral Suspension if you are pregnant or breastfeeding unless prescribed by the doctor. Avoid alcohol consumption while taking Dilantin Oral Suspension as it might cause increased dizziness. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of Dilantin Oral Suspension

Epilepsy/Seizures, Trigeminal neuralgia

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not chew, break, or crush the tablet/capsule. Suspension/Syrup/Drops: Shake the bottle well and take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Dilantin Oral Suspension belongs to the group of anticonvulsant medicines called 'hydantoins' used to treat epilepsy/seizures. Dilantin Oral Suspension is also used to control and prevent fits during or after a severe head injury or brain surgery. Dilantin Oral Suspension works by controlling the overactivity of the brain cells that cause seizures (fits). Thereby, Dilantin Oral Suspension helps in controlling epileptic fits involving spasms of the muscles and jerking. Dilantin Oral Suspension may also be used to treat trigeminal neuralgia (facial nerve pain). Dilantin Oral Suspension slows down the electrical impulses in the nerves and reduces their ability to transmit pain. Thereby treats trigeminal neuralgia.

Storage

Store in a cool and dry place away from sunlight
Side effects of Dilantin Oral Suspension 100 ml
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.
Here are the steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.

Drug Warnings

Do not take Dilantin Oral Suspension if you are allergic to any of its contents. Stop taking Dilantin Oral Suspension and consult your doctor if you develop any skin rashes (Stevens-Johnson syndrome), swollen glands (anticonvulsant hypersensitivity syndrome - AHS) or have suicidal thoughts. Talk to your doctor if you have heart, kidney, or liver problems. Avoid taking Dilantin Oral Suspension if you are pregnant or breastfeeding unless prescribed by your doctor. Avoid alcohol consumption while taking Dilantin Oral Suspension as it might cause unpleasant side effects. Let your doctor know if you have diabetes, as intake of Dilantin Oral Suspension affects the blood sugar level. Intake of Dilantin Oral Suspension may cause dizziness so be cautious while driving or operating any heavy machinery. Tell your doctor that you are taking anti-HIV medicine (like delavirdine) before intake of Dilantin Oral Suspension , as both might react with each other leading to serious conditions.

Drug-Drug Interactions

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PhenytoinRilpivirine
Critical

Drug-Drug Interactions

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PhenytoinRilpivirine
Critical
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using rilpivirine together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of rilpivirine.

How to manage the interaction:
Taking Rilpivirine with Dilantin Oral Suspension 100 ml is not recommended, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using praziquantel together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of praziquantel leading decreased effectiveness.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Praziquantelcan is not recommended as it cause an interaction, it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
PhenytoinCimetidine
Critical
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using Dilantin Oral Suspension 100 ml together with cimetidine may increase the effects of Dilantin Oral Suspension 100 ml.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Cimetidine is not recommended, it can be taken if prescribed by the doctor. Contact a doctor, if you experience twitching eye movements, slurred speech, loss of balance, tremors, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Co-administration of Dilantin Oral Suspension 100 ml and Isavuconazole may significantly reduce the blood levels of Isavuconazole, which may make Isavuconazole less effective in treating your condition.

How to manage the interaction:
Taking Isavuconazole with Dilantin Oral Suspension 100 ml is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
PhenytoinVenetoclax
Critical
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using venetoclax together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of venetoclax leading to decreased effectiveness of venetoclax in treating in your condition.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Venetoclax is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using lurasidone together with Dilantin Oral Suspension 100 ml may significantly decrease the blood levels of lurasidone.

How to manage the interaction:
Using lurasidone with Dilantin Oral Suspension 100 ml is not recommended, it can be taken if a doctor has prescribed it. Consult a doctor, if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Taking ceritinib with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels and effectiveness of Ceritinib.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Ceritinib is not recommended as it can cause an interaction, it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Using ranolazine together with Dilantin Oral Suspension 100 ml may significantly reduce the blood levels of ranolazine leading to dreceased effectiveness of ranolazine in treating your condition.

How to manage the interaction:
Taking Dilantin Oral Suspension 100 ml with Ranolazine is not recommended. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Dilantin Oral Suspension 100 ml may decrease the blood levels of mebendazole, which may make mebendazole less effective in treating your condition.

How to manage the interaction:
Although taking Dilantin Oral Suspension 100 ml and mebendazole together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Dilantin Oral Suspension 100 ml:
Coadministration of Dilantin Oral Suspension 100 ml and Crizotinib may decrease the blood levels of Crizotinib, which may make Crizotinib less effective.

How to manage the interaction:
Although taking Dilantin Oral Suspension 100 ml and Crizotinib together can result in an interaction, it can be taken if your doctor has prescribed it. Without consulting a doctor, never stop taking any drugs.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, this helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dilantin Oral Suspension works by controlling overactivity of the brain that causes seizures (fits). Thereby, Dilantin Oral Suspension helps in controlling epileptic fits involving spasms of the muscles and jerking.

Dilantin Oral Suspension can make birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Please do not stop taking Dilantin Oral Suspension without consulting your doctor as it may cause increased seizures. Continue taking Dilantin Oral Suspension for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Dilantin Oral Suspension .

Yes, Dilantin Oral Suspension may cause swelling in the gums. Brush and floss your teeth daily; visit your dentist if you experience this problem regularly.

Dilantin Oral Suspension may affect the breakdown of the blood sugar/glucose and may prevent the release of insulin, thereby leading to high blood sugar. So, contact a doctor before using Dilantin Oral Suspension if you have diabetes.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ACETAMINOPHEN
  • IBUPROFEN
  • WARFARIN
  • CLOPIDOGREL
  • CARBAMAZEPINE
  • GABAPENTIN
  • PREGABALIN
  • DIAZEPAM
  • FLUOXETINE
  • QUETIAPINE
  • FUROSEMIDE
  • ATORVASTATIN
  • SILDENAFIL
  • CHOLECALCIFEROL
  • FOLIC ACID
  • DELAVIRDINE

Special Advise

Your doctor may advise you to get regular blood tests to check for any abnormality of blood and test the amount of Dilantin Oral Suspension in your blood. 

 

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterised by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Trigeminal neuralgia: It is a condition affecting the trigeminal nerve in the face that causes painful sensations similar to electric shock on one side of the face. Symptoms include mild to severe facial pain often triggered by speaking, chewing, or brushing the teeth.

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