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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

DRONEDARONE-400MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dilsave 400 mg Tablet

Dilsave 400 mg Tablet belongs to a group of medications known as 'anti-arrhythmic' primarily used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). Besides this, Dilsave 400 mg Tablet is also used to treat 'cardioversion' which is a medical procedure that changes the abnormal heartbeat to a normal rhythm. Arrhythmia is a problem associated with the rate of rhythm at which the heartbeats.

Dilsave 400 mg Tablet contains 'Dronedarone' a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. Dilsave 400 mg Tablet blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Take Dilsave 400 mg Tablet as prescribed by your doctor. Your dose and duration of Dilsave 400 mg Tablet will be advised by your doctor, depending upon your medical condition. In some cases, you may experience slow heartbeat, diarrhoea, nausea and vomiting. Most of these side effects of Dilsave 400 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to Dilsave 400 mg Tablet or any other medicines, before starting Dilsave 400 mg Tablet . Inform your doctor if you have heart, kidney or liver problems and electrolyte imbalance. It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Dilsave 400 mg Tablet is not recommended for use during pregnancy. Do not stop taking Dilsave 400 mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. 

Uses of Dilsave 400 mg Tablet

Arrhythmia (irregular heartbeat).

Directions for Use

Tablet: Take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Medicinal Benefits

Dilsave 400 mg Tablet contains Dronedarone, a class III anti-arrhythmic drug. It treats arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). It blocks abnormal electrical signals in the heart and works by restoring normal heart rhythm. It also prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart (ventricles) beat quickly than normal). Dilsave 400 mg Tablet is used in cardioversion, a medical procedure that changes the abnormal heartbeat to a normal rhythm.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Dilsave 400 mg Tablet

  • Slow heartbeat
  • Diarrhoea
  • Increased liver enzymes
  • Nausea
  • Vomiting 
  • Abdominal pain
  • Fatigue

Drug Warnings

Brief your medical history to the doctor if you have any heart problems liver, kidney diseases and electrolyte imbalance (low potassium and magnesium) before starting Dilsave 400 mg Tablet . Dilsave 400 mg Tablet may affect QT prolongation (heart muscle takes longer than usual to recharge between beats) that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have heart-related problems like heart failure, slow heartbeat and a family history of heart diseases. Dilsave 400 mg Tablet is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using Dilsave 400 mg Tablet if you are a breastfeeding mother. Do not drive or operate machinery if you experience any side effects that affect your ability to concentrate and drive. Avoid consumption of alcohol with Dilsave 400 mg Tablet as it may decrease the efficacy of Dilsave 400 mg Tablet . Dilsave 400 mg Tablet is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

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DronedaroneAmisulpride
Critical
DronedaroneGatifloxacin
Critical

Drug-Drug Interactions

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DronedaroneAmisulpride
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Taking Amisulpride with Dilsave 400 mg Tablet can increase the risk of severe irregular heart rhythm.

How to manage the interaction:
Taking Amisulpride with Dilsave 400 mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DronedaroneGatifloxacin
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Taking Gatifloxacin with Dilsave 400 mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Dilsave 400 mg Tablet together is not recommedned as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneChloroquine
Critical
How does the drug interact with Dilsave 400 mg Tablet:
When Chloroquine is taken with Dilsave 400 mg Tablet, it may increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Chloroquine with Dilsave 400 mg Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneChlorpromazine
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Taking Chlorpromazine with Dilsave 400 mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Chlorpromazine with Dilsave 400 mg Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneAtomoxetine
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Using Dilsave 400 mg Tablet together with atomoxetine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Atomoxetine with Dilsave 400 mg Tablet is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
DronedaroneHaloperidol
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Coadministration of Dilsave 400 mg Tablet and Haloperidol can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dilsave 400 mg Tablet and Haloperidol together is generally avoided as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DronedaroneOfloxacin
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Coadministration of Ofloxacin with Dilsave 400 mg Tablet can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin with Dilsave 400 mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneHydroxyzine
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Taking Dilsave 400 mg Tablet with Hydroxyzine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Hydroxyzine with Dilsave 400 mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DronedaroneBicalutamide
Critical
How does the drug interact with Dilsave 400 mg Tablet:
When Bicalutamide is taken with Dilsave 400 mg Tablet, can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Bicalutamide with Dilsave 400 mg Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
DronedaroneAmitriptyline
Critical
How does the drug interact with Dilsave 400 mg Tablet:
Combining Amitriptyline and Dilsave 400 mg Tablet may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Amitriptyline with Dilsave 400 mg Tablet may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Dilsave 400 mg Tablet Substitute

Substitutes safety advice
  • Multaq 400Mg Tablet

    by Others

    75.60per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Dilsave 400 mg Tablet contains Dronedarone that works as an antiarrhythmic by blocking abnormal electrical signals in the heart. Thus Dilsave 400 mg Tablet helps to treat the uneven heartbeats and helps in normalising the heart rhythm.

Do not stop using Dilsave 400 mg Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms like irregular heartbeat and worsening of the disease.

Dilsave 400 mg Tablet should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), liver, kidney diseases and electrolyte imbalance (low levels of potassium and magnesium).

Store Dilsave 400 mg Tablet away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.

If you missed a dose, take Dilsave 400 mg Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • LOPINAVIR
  • RITONAVIR
  • RIFAMPIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • NEFAZODONE
  • FLIBANSERIN
  • FINGOLIMOD
  • DABIGATRAN
  • DIGOXIN

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Regular monitoring of heart function with ECG or EKG is necessary.
  • Liver and kidney function tests are recommended to rule out any chances of kidney or liver impairment.
  • Regular examinations of your electrolytes like potassium and magnesium are recommended. Prolonged use may decrease the level of potassium and magnesium level in the body. 

Disease/Condition Glossary

Arrhythmia: It is a problem associated with the rate of rhythm at which the heart beats. Generally, in this condition, the heart beats too fast, too slow or with an irregular rate. It can lead to severe heart damage. A cardiac arrhythmia occurs when there are abnormal electrical signals in the heart. When the heart beats too fast, it is known as tachycardia, and if it is too slow, it is called bradycardia. Treatment of arrhythmia includes drugs, medical procedures, implantable devices and sometimes surgery.

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