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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
COD available

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Composition :

DRONEDARONE-400MG

Manufacturer/Marketer :

Aventis Pharma

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Multaq 400Mg Tablet

Multaq 400Mg Tablet belongs to a group of medications known as 'anti-arrhythmic' primarily used to treat arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). Besides this, Multaq 400Mg Tablet is also used to treat 'cardioversion' which is a medical procedure that changes the abnormal heartbeat to a normal rhythm. Arrhythmia is a problem associated with the rate of rhythm at which the heartbeats.

Multaq 400Mg Tablet contains 'Dronedarone' a Class III anti-arrhythmic drug that restores normal heart rhythm and reduces heart rate in atrial fibrillation. Multaq 400Mg Tablet blocks abnormal electrical signals in the heart. Also, it prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart ventricles that beat quickly than normal).

Take Multaq 400Mg Tablet as prescribed by your doctor. Your dose and duration of Multaq 400Mg Tablet will be advised by your doctor, depending upon your medical condition. In some cases, you may experience slow heartbeat, diarrhoea, nausea and vomiting. Most of these side effects of Multaq 400Mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.  

Please inform your doctor if you are using any prescription, non-prescription drugs, including vitamins and herbal products. Let your doctor know if you have any allergic reactions to Multaq 400Mg Tablet or any other medicines, before starting Multaq 400Mg Tablet. Inform your doctor if you have heart, kidney or liver problems and electrolyte imbalance. It is advised to consult a doctor if you are a pregnant or breastfeeding mother. Multaq 400Mg Tablet is not recommended for use during pregnancy. Do not stop taking Multaq 400Mg Tablet without consulting your doctor since it may worsen your condition and increase the risk of future heart problems. 

Uses of Multaq 400Mg Tablet

Arrhythmia (irregular heartbeat).

Directions for Use

Tablet: Take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Medicinal Benefits

Multaq 400Mg Tablet contains Dronedarone, a class III anti-arrhythmic drug. It treats arrhythmia (irregular heartbeat) in patients with paroxysmal (sudden attack) or persistent atrial fibrillation (irregular heartbeat due to poor blood flow). It blocks abnormal electrical signals in the heart and works by restoring normal heart rhythm. It also prevents ventricular fibrillation (a rapid contraction of heart muscle) and ventricular tachycardia (lower chambers of the heart (ventricles) beat quickly than normal). Multaq 400Mg Tablet is used in cardioversion, a medical procedure that changes the abnormal heartbeat to a normal rhythm.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Multaq 400Mg Tablet

  • Slow heartbeat
  • Diarrhoea
  • Increased liver enzymes
  • Nausea
  • Vomiting 
  • Abdominal pain
  • Fatigue

Drug Warnings

Brief your medical history to the doctor if you have any heart problems liver, kidney diseases and electrolyte imbalance (low potassium and magnesium) before starting Multaq 400Mg Tablet. Multaq 400Mg Tablet may affect QT prolongation (heart muscle takes longer than usual to recharge between beats) that can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have heart-related problems like heart failure, slow heartbeat and a family history of heart diseases. Multaq 400Mg Tablet is contraindicated during pregnancy since it has harmful effects on the foetus. Consult your doctor before using Multaq 400Mg Tablet if you are a breastfeeding mother. Do not drive or operate machinery if you experience any side effects that affect your ability to concentrate and drive. Avoid consumption of alcohol with Multaq 400Mg Tablet as it may decrease the efficacy of Multaq 400Mg Tablet. Multaq 400Mg Tablet is not recommended in patients younger than 18 years of age.

Drug-Drug Interactions

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DronedaroneAtomoxetine
Critical
DronedaroneKetoconazole
Critical

Drug-Drug Interactions

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DronedaroneAtomoxetine
Critical
How does the drug interact with Multaq 400Mg Tablet:
Using Multaq 400Mg Tablet together with atomoxetine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Atomoxetine with Multaq 400Mg Tablet is not recommended, please consult a doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
DronedaroneKetoconazole
Critical
How does the drug interact with Multaq 400Mg Tablet:
When Multaq 400Mg Tablet is taken with Ketoconazole, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Ketoconazole with Multaq 400Mg Tablet is not recommended as it can cause an interaction, but it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
DronedaroneHydroxyzine
Critical
How does the drug interact with Multaq 400Mg Tablet:
Taking Multaq 400Mg Tablet with Hydroxyzine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Hydroxyzine with Multaq 400Mg Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
DronedaroneCiprofloxacin
Critical
How does the drug interact with Multaq 400Mg Tablet:
When Multaq 400Mg Tablet is taken with Ciprofloxacin, it can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions, or electrolyte disturbances (such as magnesium or potassium deficiency brought on by severe or prolonged diarrhea or vomiting), you may be at higher risk.

How to manage the interaction:
Taking Ciprofloxacin with Multaq 400Mg Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
DronedaroneAmiodarone
Critical
How does the drug interact with Multaq 400Mg Tablet:
The combination of Amiodarone and Multaq 400Mg Tablet may significantly raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Despite the fact that Amiodarone and Multaq 400Mg Tablet interact, it can be taken if prescribed by a doctor.If you have other cardiac disorders, or imbalances in electrolytes, you may be at greater risk. If you get dizziness, lightheadedness, fainting, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without visiting a doctor.
DronedaroneChlorpromazine
Critical
How does the drug interact with Multaq 400Mg Tablet:
Taking Chlorpromazine with Multaq 400Mg Tablet can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Chlorpromazine with Multaq 400Mg Tablet is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
DronedaroneMoxifloxacin
Critical
How does the drug interact with Multaq 400Mg Tablet:
Using Multaq 400Mg Tablet together with Moxifloxacin can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Multaq 400Mg Tablet is not recommended as it can lead to an interaction; it can be taken if advised by your doctor. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations.
DronedaronePosaconazole
Critical
How does the drug interact with Multaq 400Mg Tablet:
When Multaq 400Mg Tablet is taken with Posaconazole, can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Posaconazole with Multaq 400Mg Tablet is not recommended, please consult your doctor before taking it. They can be taken together if advised by your doctor. However, contact your doctor if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop taking any medications without consulting a doctor.
DronedaroneSorafenib
Critical
How does the drug interact with Multaq 400Mg Tablet:
Using Multaq 400Mg Tablet together with Sorafenib can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Sorafenib with Multaq 400Mg Tablet is generally avoided as it can cause an interaction, consult a doctor before taking it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor. Do not stop using any medications without consulting a doctor.
DronedaroneDisopyramide
Critical
How does the drug interact with Multaq 400Mg Tablet:
Taking Disopyramide with Multaq 400Mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Disopyramide with Multaq 400Mg Tablet is not recommended, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, diarrhea or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with BMI 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Limit sodium chloride intake (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega 3 fatty acid containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTIARRHYTHMICS

Multaq 400Mg Tablet Substitute

Substitutes safety advice
  • Dilsave 400 mg Tablet 10's

    by Others

    62.10per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Multaq 400Mg Tablet contains Dronedarone that works as an antiarrhythmic by blocking abnormal electrical signals in the heart. Thus Multaq 400Mg Tablet helps to treat the uneven heartbeats and helps in normalising the heart rhythm.

Do not stop using Multaq 400Mg Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms like irregular heartbeat and worsening of the disease.

Multaq 400Mg Tablet should be used with caution in cases of any allergic reactions, heart problems like heart failure, slow heartbeat, QT prolongation (heart muscle takes longer than usual to recharge between beats) in the ECG (electrocardiogram), liver, kidney diseases and electrolyte imbalance (low levels of potassium and magnesium).

Store Multaq 400Mg Tablet away from direct sunlight and at a temperature not exceeding 30°C. Keep this medicine out of sight and reach of children.

If you missed a dose, take Multaq 400Mg Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • LOPINAVIR
  • RITONAVIR
  • RIFAMPIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • PHENYTOIN
  • NEFAZODONE
  • FLIBANSERIN
  • FINGOLIMOD
  • DABIGATRAN
  • DIGOXIN

Special Advise

  • Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
  • Regular monitoring of heart function with ECG or EKG is necessary.
  • Liver and kidney function tests are recommended to rule out any chances of kidney or liver impairment.
  • Regular examinations of your electrolytes like potassium and magnesium are recommended. Prolonged use may decrease the level of potassium and magnesium level in the body. 

Disease/Condition Glossary

Arrhythmia: It is a problem associated with the rate of rhythm at which the heart beats. Generally, in this condition, the heart beats too fast, too slow or with an irregular rate. It can lead to severe heart damage. A cardiac arrhythmia occurs when there are abnormal electrical signals in the heart. When the heart beats too fast, it is known as tachycardia, and if it is too slow, it is called bradycardia. Treatment of arrhythmia includes drugs, medical procedures, implantable devices and sometimes surgery.

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