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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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Whats That

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Composition :

DOCETAXEL-200MG

Manufacturer/Marketer :

Princeps Pharmacuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Docetrust Inj - 20Mg

Docetrust Inj - 20Mg belongs to the class of 'anti-neoplastic/anti-cancer drugs', primarily used as a chemotherapy drug to treat cancers. It is effectively used in breast, lung, prostate, stomach, head/neck cancers. Cancer is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues.

Docetrust Inj - 20Mg contains Docetaxel, which belongs to the anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent, i.e., it prevents the cancer cells from rapidly dividing and spreading.

Docetrust Inj - 20Mg will be administered by a healthcare professional. Your doctor will decide the dosage depending on your medical condition. The common side effects of Docetrust Inj - 20Mg include pain/swelling at the injection site, headache, fatigue, dizziness, drowsiness, constipation, loss of appetite, indigestion, tearing of the eyes, nausea, vomiting, diarrhoea, insomnia (sleeplessness), fever (please inform your doctor if you have fever), muscle aches, and breathlessness. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Do not use or stop this medicine if the doctor did not advise you. Before starting Docetrust Inj - 20Mg, let your doctor know if you have any allergic reactions, medical history of liver or kidney diseases, heart diseases, blood pressure problems, fits, lung disorders, weak immune system, anemia, low white blood cell count, vision problems, and are receiving chemotherapy. Docetrust Inj - 20Mg is not indicated for use in pregnant and breastfeeding women. Docetrust Inj - 20Mg may make you feel dizzy and drowsy, hence do not drive or operate machinery. It is not recommended to consume alcohol along with Docetrust Inj - 20Mg. Docetrust Inj - 20Mg is not recommended for children below two years of age.

Uses of Docetrust Inj - 20Mg

Cancer.

Directions for Use

It will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Docetrust Inj - 20Mg contains Docetaxel that belongs to the family of anticancer drugs. It works by slowing down cell growth. It is a cytotoxic agent and prevents cancer cells from rapidly dividing and spreading. Docetaxel may be used alone or in combination with other chemotherapy drugs to treat breast cancer that has spread to the tissues and lymph nodes (locally advanced breast cancer) and other parts (secondary breast cancer). It is also used in prostate cancer that does not respond to hormone treatment. It is further being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers.

Storage

Store in a cool and dry place away from sunlight
Side effects of Docetrust Inj - 20Mg
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Inform your doctor if you have any allergic reactions to Docetrust Inj - 20Mg or other medications. Before starting Docetrust Inj - 20Mg, let your doctor know if you have any medical history of allergic reactions, non-small cell lung cancer, liver or kidney diseases, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Docetrust Inj - 20Mg can affect the unborn baby when used in pregnancy. It may also have harmful effects on the breastfed infant when used by a lactating mother. Hence, Docetrust Inj - 20Mg is not indicated in pregnancy and breastfeeding women. If you are using Docetrust Inj - 20Mg, use reliable contraception forms to prevent pregnancy during the course. Docetrust Inj - 20Mg can make you feel dizzy and drowsy, thus affecting your mental ability to drive. Do not drive or operate machinery if you are not mentally alert and focused. Avoid alcohol consumption while being treated with Docetrust Inj - 20Mg. Docetrust Inj - 20Mg is not recommended for patients younger than 18 years of age.

Drug-Drug Interactions

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DocetaxelErythromycin
Severe
DocetaxelInfliximab
Severe

Drug-Drug Interactions

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DocetaxelErythromycin
Severe
How does the drug interact with Docetrust Inj - 20Mg:
Erythromycin may significantly increase Docetrust Inj - 20Mg blood levels. This may increase the possibility of Docetrust Inj - 20Mg side effects.

How to manage the interaction:
Although taking erythromycin and ceritinib together can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult your doctor if you experience fatigue, confusion, unusual bruising or bleeding, fever, shivers, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, urination discomfort or burning. Do not discontinue any medications without consulting a doctor.
DocetaxelInfliximab
Severe
How does the drug interact with Docetrust Inj - 20Mg:
When Docetrust Inj - 20Mg is taken with Infliximab, it can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Docetrust Inj - 20Mg together can result in an interaction, but it can be taken if your doctor has advised it. If you have any symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
DocetaxelClozapine
Severe
How does the drug interact with Docetrust Inj - 20Mg:
Taking Docetrust Inj - 20Mg and clozapine can increase the risk of infection.

How to manage the interaction:
There may be a possibility of interaction between Docetrust Inj - 20Mg and Clozapine, but it can be taken if prescribed by a doctor. If you're taking clozapine and also taking medications that can affect your bone marrow or cause agranulocytosis, be careful and get regular check-ups. If you notice any symptoms like infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain while urinating, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
DocetaxelMifepristone
Severe
How does the drug interact with Docetrust Inj - 20Mg:
Co-administration of Docetrust Inj - 20Mg with mifepristone may significantly increase the levels of mifepristone, which may increase the risk of side effects.

How to manage the interaction:
Taking Docetrust Inj - 20Mg with mifepristone together can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience symptoms such as pale skin, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in phlegm(coughing fluid), red or inflamed skin, body sores, and pain or burning sensation during urination. Do not discontinue any medications without consulting a doctor.
DocetaxelRitonavir
Severe
How does the drug interact with Docetrust Inj - 20Mg:
Taking Ritonavir and Docetrust Inj - 20Mg may significantly increase the blood levels of Docetrust Inj - 20Mg.

How to manage the interaction:
Taking Docetrust Inj - 20Mg with Ritonavir together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms feeling sick, having diarrhea, sores in your mouth, retaining fluids, experiencing nerve pain, numbness or tingling, muscle pain or weakness, feeling tired, dizzy or faint, having trouble with bleeding or bruising, having a fever or chills, a sore throat, muscle aches, difficulty breathing, feeling pain or burning when you pee, or bleeding contact a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelCladribine
Severe
How does the drug interact with Docetrust Inj - 20Mg:
The combined use of cladribine with Docetrust Inj - 20Mg can increase the risk of serious infections.

How to manage the interaction:
Taking Docetrust Inj - 20Mg with Cladribine together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
DocetaxelEtanercept
Severe
How does the drug interact with Docetrust Inj - 20Mg:
When Etanercept is used with Docetrust Inj - 20Mg, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Docetrust Inj - 20Mg can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
DocetaxelDiltiazem
Severe
How does the drug interact with Docetrust Inj - 20Mg:
When Diltiazem is taken with Docetrust Inj - 20Mg, it can slow down the breakdown of Docetrust Inj - 20Mg in the body.

How to manage the interaction:
Taking Diltiazem with Docetrust Inj - 20Mg together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms like feeling sick, throwing up, having diarrhea, mouth sores, swelling, nerve pain, or weakness, it's important to let your doctor know. They might have other options for you that won't cause these problems. Other symptoms like feeling tired, dizzy, or having trouble breathing, losing weight, or pain when you pee should also be reported to your doctor right away. Do not stop using any medications without first talking to your doctor.
DocetaxelKetoconazole
Severe
How does the drug interact with Docetrust Inj - 20Mg:
Coadministration of Ketoconazole and Docetrust Inj - 20Mg may significantly increase the blood levels of Docetrust Inj - 20Mg. This may increase risk of side effects.

How to manage the interaction:
Although taking Ketoconazole and Docetrust Inj - 20Mg together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in your coughing, weight loss, red or inflamed skin, body sores, or discomfort or burning when urinating, you should consult a doctor immediately. do not discontinue any medication without consulting a doctor.
DocetaxelPosaconazole
Severe
How does the drug interact with Docetrust Inj - 20Mg:
Taking Docetrust Inj - 20Mg with posaconazole can increase the blood levels of Docetrust Inj - 20Mg. This may increase the risk of side effects.

How to manage the interaction:
Although using Posaconazole and Docetrust Inj - 20Mg together can result in an interaction, they can be taken together if advised by your doctor. However, contact your doctor if you experience vomiting, diarrhea, mouth sores, nerve pain, numbness, tingling, muscle pain or weakness. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables, and whole grains.
  • Include fish, soy, tomatoes, Brussels sprouts, kale, broccoli, and oils containing omega-3 fatty acids such as olive oil as these foods may reduce the risk of prostate cancer.
  • Include whole grains, legumes, and follow a plant-based diet. Limiting dietary fats is advised during the breast cancer phase. Instead, include healthy fats, such as olive oil, avocado, nuts, seeds, and fatty fish
  • Avoid grilled meat, red meat, saturated fat found in animal products, milk, and dairy products.
  • Exercise regularly to lose weight as obesity is also considered a risk factor for prostate cancer.
  • Eat at regular intervals.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Docetrust Inj - 20Mg Substitute

Substitutes safety advice
  • Docetere Rfa 120Mg/6Ml Inj

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  • Chemodoc 80Mg/2.0Ml Inj

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    4744.95per tablet
  • Chemotere * 120Mg*3Ml Inj

    by AYUR

    3881.33per tablet
  • Chemotere * 20Mg/0.5Ml Inj

    by AYUR

    2378.00per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Docetrust Inj - 20Mg contains Docetaxel, an anti-neoplastic agent. It prevents the cancer cells from rapidly dividing and spreading, thus slowing down their growth.

Docetrust Inj - 20Mg should be used with caution and under doctor's supervision only if you have any medical history of any allergic reactions, liver or kidney diseases, non-small cell lung cancer, heart diseases (congestive heart failure), blood pressure problems, fits, lung disorders (pulmonary effusions (excess fluid around lungs), weak immune system, anemia, low white blood cell count/thrombocytopenia, vision problems, and are already receiving chemotherapy. Let your doctor know if you have any other medical concerns before using Docetrust Inj - 20Mg.

During treatment with Docetrust Inj - 20Mg, it is essential to look for any signs of swelling (fluid retention/oedema), dizziness/fainting, difficulty in breathing, irregular heartbeat, swelling, pain and tenderness in the abdomen region, blood in stools, skin rashes, easy bleeding or bruising, sores in the mouth or throat or symptoms of infection like fever and sore throat. If you further notice any symptoms that are not manageable or unusual, please seek prompt medical attention.

It is advised to consult your doctor before undergoing any vaccination and take advice accordingly. Also, please avoid contact with people who have recently been vaccinated with the oral polio vaccine.

Docetaxel might cause serious allergic reactions and fluid retention if you had previously experienced allergic reactions with paclitaxel and cabazitaxel. These medicines contain polysorbate 80, an excipient. If you had any allergic reactions with medicines containing polysorbate 80, Docetrust Inj - 20Mg is not recommended. Please consult your doctor for more information.

Drug-Drug Interactions Checker List

  • ITRACONAZOLE
  • ERYTHROMYCIN
  • RIFABUTIN
  • METRONIDAZOLE
  • TINIDAZOLE
  • RITONAVIR
  • DISULFIRAM
  • CODEINE
  • HYDROCODONE
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE

Special Advise

  • Your doctor may advise regular physical exams and mammograms to rule out the possibility of breast cancer.
  • Self-examine your breasts to check for any lumps monthly.
  • Your doctor may also advise liver function tests to monitor your liver health.
  • Your doctor may advise blood tests and regular examinations of the prostate.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation, and stem cell therapy.

Breast cancer:  It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue, or the fibrous connective tissue within the breast. Symptoms include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size, or appearance of the breast, and a lump or swelling under the arm. 

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