Domi Up Spray 15ml belongs to a group of medications called ' anti-emetics' primarily used in the prevention of vomiting (being sick) and nausea (feeling sick) that usually occur after cancer chemotherapy, radiation treatment or surgery. Nausea is an uneasy feeling in which a person feels an urge to vomit while vomiting is the natural response to the body to forcefully discharge the stomach contents.

Domi Up Spray 15ml contains 'Ondanestron' that works by blocking the action of a chemical in the body (serotonin) responsible for causing nausea and vomiting. As a result, Domi Up Spray 15ml prevents the sensation of nausea and vomiting caused due to conditions like surgery, cancer chemotherapy, pregnancy or motion sickness.

Take Domi Up Spray 15ml as prescribed. Your doctor will advise you on how often you take Domi Up Spray 15ml based on your medical condition. A person taking Domi Up Spray 15ml often experience side effects that include a feeling of warmth, constipation, headache, diarrhoea, headache, drowsiness, feeling of tiredness. Although, not every person faces the side effects of Domi Up Spray 15ml, and even some of the unpleasant effects of Domi Up Spray 15ml do not require medical attention.

The use of Domi Up Spray 15ml is restricted in persons who are allergic to any of the ingredients present in this medicine. Tell your doctor if you are facing liver, kidney, or heart disorders. Domi Up Spray 15ml should be used during pregnancy or breastfeeding after consulting a doctor. Domi Up Spray 15ml contains lactose so tell your doctor if you have an intolerance to some sugars.

Domi Up Spray 15ml belongs to a group of medications called anti-emetics used to prevent nausea and vomiting associated with conditions like cancer chemotherapy, radiotherapy, surgery, pregnancy and motion sickness in adults and children above 4 years of age. When serotonin level increases in the blood, it stimulates the CTZ receptor (chemoreceptor trigger zone) located in the brain responsible for controlling nausea and vomiting. Domi Up Spray 15ml acts by inhibiting the release of this serotonin, thereby preventing nausea and vomiting. 

• Sensations of flushing
• Constipation
• Headache
• Confusion
• Dizziness
• Fast heartbeat
• Fever
• Headache
• Shortness of breath
• Weakness

Tell your doctor if you are dealing with an uneven heart, liver problems, or any other problem. Tell your doctor if you are taking medicine for epilepsy, cancer medicines, and abnormal heartbeats. Domi Up Spray 15ml may affect a person's ability to drive. Therefore, should avoid driving or operating any machine. People with an irregular heartbeat (arrhythmia), and phenylketonuria (too much of protein phenylalanine in the blood) should not take Domi Up Spray 15ml as it may cause serious conditions. The liver patient should not take more than 8 mg of Domi Up Spray 15ml daily. Domi Up Spray 15ml should be used during pregnancy or breastfeeding after consultation with a doctor. Taking Domi Up Spray 15ml with apomorphine can cause a sharp dip in blood pressure, even leading to death, so avoid its intake together.

Drug-Drug Interaction: Domi Up Spray 15ml may cause a serious reaction when used with certain medicines like pain killers (acetaminophen, tramadol, ibuprofen), anti-anxiety (pregabalin, lorazepam), and antiparkinson medicine (apomorphine). 

Drug-Food Interaction: No interaction found.

Drug-Disease Interaction: The use of Domi Up Spray 15ml is restricted in people with hypokalemia (low potassium) and severe liver disease. 

• ACETAMINOPHEN
• TRAMADOL
• IBUPROFEN
• PREGABALIN
• LORAZEPAM

• A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting. 
• One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
• Eat cool foods instead of hot and spicy foods.
• Include clear broths, non-fat yoghurt, fruit juice, sherbet, and sports drinks for fluid make up which has got lost due to vomiting. 

• Do not use Domi Up Spray 15ml with Apomorphine as it can cause a sudden fall of blood pressure leading to death or coma.
• Domi Up Spray 15ml contains 'phenylalanine' so if you have Phenylketonuria (PKU) avoid its intake. 

Nausea/Vomiting: Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels with a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach. Usually, a person faces nausea and vomiting as the unpleasant effects of cancer therapy after chemotherapy and radiation therapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition, and dehydration.