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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Manufacturer/Marketer :

Maneesh Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Doxinate OD Tablet

Doxinate OD Tablet belongs to the class of medications called anti-emetics primarily used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy. Morning sickness (nausea and vomiting during pregnancy) is a common symptom of pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalances and weight loss in pregnant women. 

Doxinate OD Tablet is a combination of two drugs, namely: Doxylamine and Pyridoxine (vitamin B6). Doxylamine belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/Vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine works by increasing the level of vitamin B6 in the body and helps in treating nausea and vomiting during pregnancy.

Take Doxinate OD Tablet as prescribed. You are advised to take Doxinate OD Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as drowsiness, constipation, dizziness, or blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are allergic to Doxinate OD Tablet or any other medicines, please tell your doctor. Doxinate OD Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Doxinate OD Tablet should not be given to children as safety and efficacy have not been established. Doxinate OD Tablet may cause dizziness, therefore drive with caution. Avoid consuming alcohol along with Doxinate OD Tablet as it could lead to increased dizziness. If you are taking MAO inhibitors, inform your doctor as taking them along with Doxinate OD Tablet may cause unpleasant side effects.

Uses of Doxinate OD Tablet

Nausea and vomiting in pregnancy

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Doxinate OD Tablet is a combination of two drugs, namely: Doxylamine and Pyridoxine (vitamin B6) used to treat nausea and vomiting during pregnancy. It prevents the feeling of nausea and sickness in pregnant women. Besides this, it also provides nutrition to the body. Doxylamine belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/Vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine works by increasing the level of vitamin B6 in the body and treating nausea and vomiting during pregnancy.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Doxinate OD Tablet if you are allergic to any of its contents. Tell your doctor if you have asthma, increased eye pressure, narrow-angle glaucoma, stomach ulcer, a blockage in your gut (digestive tract), liver or kidney problems. Inform your doctor if you are taking medicines for depression, cough or cold medicines, sleeping medicines, or certain pain medicines. Doxinate OD Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Doxinate OD Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Doxinate OD Tablet as it could lead to increased dizziness. 

Drug-Drug Interactions

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DoxylaminePotassium citrate
Severe

Drug-Drug Interactions

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How does the drug interact with Doxinate OD Tablet:
Taking Doxinate OD Tablet with tranylcypromine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
There may be a possibility of interaction between Doxinate OD Tablet and Tranylcypromine, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
DoxylaminePotassium citrate
Severe
How does the drug interact with Doxinate OD Tablet:
Taking Doxinate OD Tablet and Potassium citrate (in tablet or capsule form) together can increase the risk of stomach ulcers, bleeding, and other gastrointestinal injury.

How to manage the interaction:
There may be a possibility of interaction between Potassium citrate and Doxinate OD Tablet, but it can be taken if prescribed by a doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Doxinate OD Tablet:
Taking Doxinate OD Tablet with Fentanyl together can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Doxinate OD Tablet with Fentanyl can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor immediately if you feel drowsiness, loss of balance, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take a healthy diet that includes fruits, vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products.
  • One should avoid taking greasy or oily foods as they trigger nausea and vomiting.
  • Eat cool foods instead of hot and spicy foods.
  • Include clear broths, non-fat yoghurt, fruit juice, sherbet and sports drinks for fluid make up which has been lost due to vomiting.
  • Include more cool beverages in your food like clear soup, and flavoured gelatin. Also, when you drink with a straw, sip slowly to avoid swallowing air, it may lead to gas and acidity.
  • Consume liquids at least 30 minutes after eating food.

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • ARIPIPRAZOLE
  • DIPHENHYDRAMINE

Special Advise

  • Do not use Doxinate OD Tablet if you have used monoamine oxidase inhibitors (MAOIs) (anti-depressant drugs) in the past 14 days as it can cause a sudden fall in blood pressure and also it could lead to increased dizziness and drowsiness.

Disease/Condition Glossary

Morning sickness (nausea and vomiting) is a common symptom of pregnancy. It happens within the first trimester (first four months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalances and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy. Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach.

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