Doxylamine+pyridoxine
About
Doxylamine+pyridoxine belongs to the class of medications called anti-emetics primarily used to treat nausea (feeling sick) and vomiting (being sick) during pregnancy. Morning sickness (nausea and vomiting during pregnancy) is a common symptom of pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalances and weight loss in pregnant women.
Doxylamine+pyridoxine is a combination of two drugs, namely: Doxylamine and Pyridoxine (vitamin B6). Doxylamine belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/Vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine works by increasing the level of vitamin B6 in the body and helps in treating nausea and vomiting during pregnancy.
Take Doxylamine+pyridoxine as prescribed. You are advised to take Doxylamine+pyridoxine for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as drowsiness, constipation, dizziness, or blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
If you are allergic to Doxylamine+pyridoxine or any other medicines, please tell your doctor. Doxylamine+pyridoxine should not be taken by breastfeeding mothers as it passes into breast milk. Doxylamine+pyridoxine should not be given to children as safety and efficacy have not been established. Doxylamine+pyridoxine may cause dizziness, therefore drive with caution. Avoid consuming alcohol along with Doxylamine+pyridoxine as it could lead to increased dizziness. If you are taking MAO inhibitors, inform your doctor as taking them along with Doxylamine+pyridoxine may cause unpleasant side effects.
Uses of Doxylamine+pyridoxine
Medicinal Benefits
Doxylamine+pyridoxine is a combination of two drugs, namely: Doxylamine and Pyridoxine (vitamin B6) used to treat nausea and vomiting during pregnancy. It prevents the feeling of nausea and sickness in pregnant women. Besides this, it also provides nutrition to the body. Doxylamine belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/Vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxine works by increasing the level of vitamin B6 in the body and treating nausea and vomiting during pregnancy.
Directions for Use
Storage
Side Effects of Doxylamine+pyridoxine
- Drowsiness
- Dizziness
- Blurred vision
- Constipation
In-Depth Precautions and Warning
Drug Warnings
Do not take Doxylamine+pyridoxine if you are allergic to any of its contents. Tell your doctor if you have asthma, increased eye pressure, narrow-angle glaucoma, stomach ulcer, a blockage in your gut (digestive tract), liver or kidney problems. Inform your doctor if you are taking medicines for depression, cough or cold medicines, sleeping medicines, or certain pain medicines. Doxylamine+pyridoxine should not be taken by breastfeeding mothers as it passes into breast milk. Doxylamine+pyridoxine should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Doxylamine+pyridoxine as it could lead to increased dizziness.
Drug Interactions
Drug-Drug Interactions: Doxylamine+pyridoxine may have an interaction with anti-psychotic (aripiprazole), an antihistamine (diphenhydramine).
Drug-Food Interactions: You are recommended to avoid alcohol consumption while taking Doxylamine+pyridoxine. It could lead to increased dizziness and drowsiness.
Drug-Disease Interactions: Inform your doctor before taking the Doxylamine+pyridoxine if you have had depression, asthma, liver disease, or glaucoma.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended to avoid alcohol consumption while taking Doxylamine+pyridoxine as it could lead to increased dizziness and drowsiness.
Pregnancy
safe if prescribedDoxylamine+pyridoxine is intended for use in pregnant women. Consult your doctor if you have any concerns.
Breast Feeding
unsafeIt is not recommended to take Doxylamine+pyridoxine while you are breastfeeding as it passes into breast milk. Consult your doctor if you have any concerns.
Driving
cautionDoxylamine+pyridoxine may cause dizziness, drowsiness, and tiredness. Therefore, do not drive or operate heavy machinery if you feel dizzy.
Liver
cautionConsult your doctor if you have a liver disease/hepatic impairment or any concerns regarding this.
Kidney
cautionConsult your doctor if you have kidney disease/renal impairment or any concerns regarding this.
Children
unsafeDoxylamine+pyridoxine is not recommended for children as efficacy and safety have not been established.
Habit Forming
Diet & Lifestyle Advise
- Take a healthy diet that includes fruits, vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils, and low-fat dairy products.
- One should avoid taking greasy or oily foods as they trigger nausea and vomiting.
- Eat cool foods instead of hot and spicy foods.
- Include clear broths, non-fat yoghurt, fruit juice, sherbet and sports drinks for fluid make up which has been lost due to vomiting.
- Include more cool beverages in your food like clear soup, and flavoured gelatin. Also, when you drink with a straw, sip slowly to avoid swallowing air, it may lead to gas and acidity.
- Consume liquids at least 30 minutes after eating food.
Special Advise
- Do not use Doxylamine+pyridoxine if you have used monoamine oxidase inhibitors (MAOIs) (anti-depressant drugs) in the past 14 days as it can cause a sudden fall in blood pressure and also it could lead to increased dizziness and drowsiness.
Patients Concern
Disease/Condition Glossary
Morning sickness (nausea and vomiting) is a common symptom of pregnancy. It happens within the first trimester (first four months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalances and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy. Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting. While vomiting is a natural response of the body in which a person wants to expel stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain, or irritation to the stomach.
FAQs
Doxylamine+pyridoxine contains Doxylamine and Pyridoxine (vitamin B6). Doxylamine belongs to the class of antihistamines that works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine works by increasing the level of vitamin B6 in the body and treating nausea and vomiting during pregnancy.
If you or someone else have taken too much of Doxylamine+pyridoxine, contact your doctor or nearest hospital casualty department.
Doxylamine+pyridoxine may cause dizziness and sleepiness. Drive only if you are alert and omit driving and operating machinery if you feel dizzy or sleepy.
Do not discontinue Doxylamine+pyridoxine without consulting your doctor. To treat your condition effectually, continue taking Doxylamine+pyridoxine for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Doxylamine+pyridoxine.
Common side effects of Doxylamine+pyridoxine include dizziness, stomach pain, constipation, dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
