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  1. Home
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  3. Dulane M 20 Capsule 10's

Written By ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

DULOXETINE-20MG + MECOBALAMIN-1.5MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Dulane M 20 Capsule

Dulane M 20 Capsule is a combination medicine used for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain due to nerve damage or a malfunctioning nervous system. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation.

Dulane M 20 Capsule is a combination of two medicines: Duloxetine (mood stabilizer), and Mecobalamin (vitamin B12). Duloxetine is a serotonin-noradrenaline reuptake inhibitor (SNRI). It works by enhancing the amount of mood-enhancing chemicals serotonin and noradrenaline in the brain. This Dulane M 20 Capsule action balances out negative emotions and improves mood, sleep, and makes a person live a better life. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a myelin substance. Together, Dulane M 20 Capsule helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Take Dulane M 20 Capsule as prescribed. You are advised to take Dulane M 20 Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, constipation, headache, drowsiness, dry mouth, insomnia (difficulty in sleeping), erectile dysfunction, and low sexual desire. Most of these side effects of Dulane M 20 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Dulane M 20 Capsule for as long as your doctor has prescribed. Please do not stop taking Dulane M 20 Capsule without consulting your doctor as it could cause withdrawal symptoms. Keep your doctor informed about your health condition and medicines to rule out any side effects. Dulane M 20 Capsule should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Dulane M 20 Capsule as it could lead to increased dizziness and sleepiness. Do not take Dulane M 20 Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Inform your doctor immediately, if you experience suicidal thoughts after taking Dulane M 20 Capsule . Also, seek medical help immediately if you have serotonin syndrome symptoms, such as agitation, hallucinations, fever, shivering, muscle stiffness, twitching, nausea, vomiting, or diarrhoea.

Uses of Dulane M 20 Capsule

Neuropathic pain

Directions for Use

Take Dulane M 20 Capsule with or without food as advised by the doctor. Swallow it as a whole with a glass of water, do not chew or break it.

Medicinal Benefits

Dulane M 20 Capsule is used to treat neuropathic pain in adults. Dulane M 20 Capsule is a combination of two medicines: Duloxetine (mood stabilizer), Mecobalamin (vitamin B12). Gabapentin treats seizures by balancing a chemical messenger in the brain called a neurotransmitter, thereby decreasing its abnormal excitement in the brain. Mecobalamin is a Vitamin B12 that helps rejuvenate and protect damaged nerve cells by producing a myelin substance. Together, Dulane M 20 Capsule helps provide relief from neuropathic pain caused due to nerve damage and other neurological disorders.

Storage

Keep Dulane M 20 Capsule out of the sight and reach of children.
Side effects of Dulane M 20 Capsule
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.

Drug Warnings

Do not take Dulane M 20 Capsule if you are allergic to any of its contents. Inform your doctor before taking Dulane M 20 Capsule if you have liver or kidney disease, slow digestion, bleeding problems, narrow-angle glaucoma, bipolar disorder. Avoid taking Dulane M 20 Capsule within 5 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, methylene blue injection, linezolid, phenelzine, selegiline, or tranylcypromine. Please do not stop taking Dulane M 20 Capsule without consulting your doctor as it could cause withdrawal symptoms. Dulane M 20 Capsule causes drowsiness and dizziness, so drive only if you are alert. Dulane M 20 Capsule should not be given to children as safety and effectiveness have not been established. Consult your doctor immediately if you experience suicidal tendencies. Do not take Dulane M 20 Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Do not get up too fast from a sitting or lying position. Please do not drink alcohol as it may increase your risk of liver damage.

Drug-Drug Interactions

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DuloxetineTranylcypromine
Critical
DuloxetineSelegiline
Critical

Drug-Drug Interactions

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DuloxetineTranylcypromine
Critical
How does the drug interact with Dulane M 20 Capsule:
Taking Tranylcypromine with Dulane M 20 Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Dulane M 20 Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles or stiffness, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineSelegiline
Critical
How does the drug interact with Dulane M 20 Capsule:
Taking Dulane M 20 Capsule with selegiline may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Although there is an interaction between Dulane M 20 Capsule and Selegiline, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineSafinamide
Critical
How does the drug interact with Dulane M 20 Capsule:
Coadministration of safinamide with Dulane M 20 Capsule can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Safinamide with Dulane M 20 Capsule is not recommended as it can result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetinePhenelzine
Critical
How does the drug interact with Dulane M 20 Capsule:
Taking phenelzine with Dulane M 20 Capsule can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dulane M 20 Capsule with Phenelzine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineRasagiline
Critical
How does the drug interact with Dulane M 20 Capsule:
Taking Rasagiline with Dulane M 20 Capsule can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Rasagiline and Dulane M 20 Capsule is not recommended as they can possibly result in an interaction, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, pain in the muscles, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting a doctor.
DuloxetineEliglustat
Critical
How does the drug interact with Dulane M 20 Capsule:
Coadministration of eliglustat and Dulane M 20 Capsule can significantly increase the blood levels of eliglustat. This may increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Dulane M 20 Capsule with Eliglustat is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, or weak pulse. Do not discontinue any medications without consulting your doctor.
DuloxetineLinezolid
Critical
How does the drug interact with Dulane M 20 Capsule:
Taking Dulane M 20 Capsule with Linezolid can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Dulane M 20 Capsule with Linezolid is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting a doctor.
DuloxetineMetoclopramide
Critical
How does the drug interact with Dulane M 20 Capsule:
Coadministration of metoclopramide with Dulane M 20 Capsule increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Metoclopramide with Dulane M 20 Capsule is not recommended, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
DuloxetineProcarbazine
Critical
How does the drug interact with Dulane M 20 Capsule:
Taking Dulane M 20 Capsule with procarbazine can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Dulane M 20 Capsule with Procarbazine is not recommended, but they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering or shaking, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhoea. Do not discontinue any medications without consulting your doctor.
DuloxetineEscitalopram
Severe
How does the drug interact with Dulane M 20 Capsule:
Taking Dulane M 20 Capsule with Escitalopram can increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Although taking Dulane M 20 Capsule with Escitalopram can possibly result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, fever, excessive sweating, shivering, blurred vision, pain in the muscles, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet to improve nerve health and prevent nerve pain.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath as it can be soothing. It helps in increasing blood circulation, thereby decreasing numbness and pain.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.
  • Physical relaxation and massages can help provide symptomatic relief.
  • Learn about techniques for sitting, stretching, moving, and standing from a physical or occupational therapist. These can help prevent pain.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation and boosts healing.

Side Effects of Dulane M 20 Capsule

  • Nausea
  • Constipation
  • Headache
  • Insomnia (difficulty in sleeping)
  • Erectile dysfunction
  • Low sexual desire
  • Dry mouth
  • Drowsiness

Habit Forming

Yes

Therapeutic Class

ANTIDEPRESSANT

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, some young people who have taken Dulane M 20 Capsule have experienced suicidal thoughts, so people of that age group should be monitored closely while on Dulane M 20 Capsule . Do not be reluctant to speak with your doctor immediately if you experience suicidal tendencies.

Yes, Dulane M 20 Capsule may rarely cause weight gain, but is not experienced by everyone. Follow the regular diet and exercise to maintain a healthy weight.

Dry mouth could be a side-effect of Dulane M 20 Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Do not discontinue Dulane M 20 Capsule without consulting your doctor as it could lead to withdrawal symptoms. To treat your condition effectually continue taking Dulane M 20 Capsule for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Dulane M 20 Capsule ; your doctor will reduce the dose gradually.

Dulane M 20 Capsule is used to treat neuropathic pain due to diabetic neuropathy. Diabetic neuropathy is a condition in which nerve damage occurs due to high blood glucose levels. It mostly damages the nerves in legs and feet.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • DICLOFENAC
  • INDOMETHACIN
  • MELOXICAM

Special Advise

  • Close monitoring for suicidal thoughts/behavior is required for people using Dulane M 20 Capsule .
  • Using Dulane M 20 Capsule in children can cause emotional changes, aggressive behavior, concentration problems, restlessness, school performance changes, and hyperactivity.

Disease/Condition Glossary

Neuropathic pain: It is a nervous system disorder caused due to damage to sensory nerves. It is caused by chronic progressive nerve disease or due to infection or injury. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

Health Queries

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Dulane M 20 Capsule as it may increase dizziness and sleepiness.

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Pregnancy

Caution

Avoid taking Dulane M 20 Capsule if you are pregnant unless prescribed by a doctor. Please consult your doctor if you have any concerns regarding this, your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Dulane M 20 Capsule ; your doctor will decide whether Dulane M 20 Capsule can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Dulane M 20 Capsule causes drowsiness, sleepiness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Dulane M 20 Capsule should not be given to children and adolescents aged less than 18 years of age.

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