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  3. Duocin 250 mg Tablet 10's

Duocin 250 mg Tablet 10's, Pack of 10
Written By ,
Reviewed By Sureshvarma D , MPharma
Non returnable*
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Composition :

CEFUROXIME-250MG + LACTOBACILLUS-120MILLION SPORES

Manufacturer/Marketer :

Apellon Biotech

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Duocin 250 mg Tablet

Duocin 250 mg Tablet belongs to a class of medication called antibiotics used to treat bacterial infections of the urinary tract, blood, bones, joints, heart, lungs, brain, chest, ears, skin, or soft tissues. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Duocin 250 mg Tablet does not work against infections caused by the virus.

Duocin 250 mg Tablet contains Cefuroxime (antibiotic) and Lactobacillus (probiotic). Cefuroxime works by interfering with the formation of the bacterial cell wall (a protective covering) necessary for survival. Thereby damaging the bacterial cell wall and killing bacteria. Lactobacillus helps to restore good bacteria in the intestines. Thereby, it prevents diarrhoea and loss of beneficial bacteria due to the prolonged intake of antibiotics.

You are advised to take Duocin 250 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Duocin 250 mg Tablet may cause side effects like nausea, vomiting, bloating, diarrhoea, allergic reaction, and increased liver enzymes. Most of these side effects of Duocin 250 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Duocin 250 mg Tablet , penicillins, cephalosporin antibiotics, or any other medicines. If you are pregnant or breastfeeding, inform your doctor before taking Duocin 250 mg Tablet . Duocin 250 mg Tablet is not recommended for infants below six months of age as the safety and effectiveness were not established. Drive only if you are alert, as Duocin 250 mg Tablet may cause dizziness. People with liver and kidney problems should take Duocin 250 mg Tablet with caution.

Uses of Duocin 250 mg Tablet

Bacterial infections

Directions for Use

Swallow Duocin 250 mg Tablet as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

Duocin 250 mg Tablet consists of Cefuroxime and Lactobacillus, used to treat bacterial infections. Cefuroxime is a broad-spectrum antibiotic that acts against aerobic (grows in the presence of oxygen), anaerobic (grows in the absence of oxygen) gram-negative and gram-positive bacteria. It interferes with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thus, it damages the bacterial cell wall and kills bacteria. Lactobacillus is a probiotic (live microorganisms that keep the body healthy) that helps restore good bacteria in the intestines. Thus, it prevents diarrhoea and loss of beneficial bacteria due to the prolonged intake of antibiotics.

Storage

Store in a cool and dry place away from sunlight
Side effects of Duocin 250 mg Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Inflammation of Vagina needs immediate attention and cannot be ignored.
  • Get a physical examination and prevent wearing clothes that can hold heat and moisture.
  • Avoid using vaginal sprays or perfumed soaps that increase itching and irritation.
  • Follow your doctor's instructions, and rest well with proper medication.
  • Take a balanced diet and get regular screenings to reduce inflammation.

Drug Warnings

Please tell your doctor if you are allergic to Duocin 250 mg Tablet , penicillins, cephalosporin antibiotics, or any other medicines. If you have diabetes, kidney or liver problems, a weak immune system, or inflammation of the large intestine, inform your doctor before taking Duocin 250 mg Tablet . If you are pregnant or breastfeeding, consult a doctor before taking Duocin 250 mg Tablet . Duocin 250 mg Tablet is not recommended for babies below three months of age, as the safety and effectiveness were not established. Drive only if you are alert, as Duocin 250 mg Tablet may cause dizziness.

Drug-Drug Interactions

verifiedApollotooltip
CefuroximeLepirudin
Severe
CefuroximeBCG vaccine
Severe

Drug-Drug Interactions

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CefuroximeLepirudin
Severe
How does the drug interact with Duocin 250 mg Tablet:
The therapeutic efficacy of Lepirudin can be decreased when used in combination with Duocin 250 mg Tablet.

How to manage the interaction:
Although taking Duocin 250 mg Tablet and Lepirudin together can evidently cause an interaction, it can be taken if your doctor has suggested it. Do not stop using any medications without a doctor's advice.
CefuroximeBCG vaccine
Severe
How does the drug interact with Duocin 250 mg Tablet:
Co-administration of Duocin 250 mg Tablet may reduce the anti-tumor activity of BCG in the bladder.

How to manage the interaction:
Talk to your doctor before receiving BCG if you are currently being treated with Duocin 250 mg Tablet. To ensure adequate response to your treatment, you should not receive BCG until after you complete your antibiotic therapy. Do not discontinue the medication without consulting a doctor.
CefuroximeDalteparin
Severe
How does the drug interact with Duocin 250 mg Tablet:
Co-administration of Dalteparin and Duocin 250 mg Tablet can increase the blood levels and effects of Dlateparin.

How to manage the interaction:
Taking Duocin 250 mg Tablet with Dalteparin together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
CefuroximeRanitidine
Moderate
How does the drug interact with Duocin 250 mg Tablet:
Taking these medications together might make it harder for your body to absorb atazanavir, which could make it less effective.

How to manage the interaction:
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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the entire course of Duocin 250 mg Tablet to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea.
  • Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can help restore the intestine's good bacteria.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids daily while taking Duocin 250 mg Tablet .
  • Avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Duocin 250 mg Tablet Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

verifiedApollotooltip
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESOther gastroenteritis and colitis of infectious and unspecified origin
Severe
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESChronic kidney disease
Moderate

Drug-Diseases Interactions

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CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESOther gastroenteritis and colitis of infectious and unspecified origin
Severe
How does the disease interact with Duocin 250 mg Tablet:
Colitis: In some cases the use of Duocin 250 mg Tablet may cause ranging from mild diarrhea to fatal colitis. Colitis is commonly Clostridioides difficile-associated diarrhea (CDAD). Discontinue therapy if signs of CDAD are confirmed.

How to manage the interaction:
Antibiotics may cause Clostridioides difficile-associated diarrhoea (CDAD), which may range from mild diarrhoea to fatal colitis. Duocin 250 mg Tablet should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the colon) or pseudomembranous colitis (a severe inflammation of the inner lining of the large intestine). Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile, and surgical evaluation is advised.
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESChronic kidney disease
Moderate
How does the disease interact with Duocin 250 mg Tablet:
Renal dysfunction: Duocin 250 mg Tablet is eliminated by the kidney in an unchanged form. Thus the plasma levels of the drug increase and prolongs the half-life. Adjust the doses of Duocin 250 mg Tablet as necessary.

How to manage the interaction:
The serum concentration may be increased in patients with impaired kidney function as most beta-lactam antibiotics are eliminated by the kidney. Dose adjustment may be necessary for patients with kidney dysfunction. Regular renal function tests are advised during prolonged or high-dose therapy.
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESDependence on enabling machines and devices, not elsewhere classified
Moderate
How does the disease interact with Duocin 250 mg Tablet:
Dialysis : Most of the antibiotics are eliminated by hemodialysis. Therefore, administer Duocin 250 mg Tablet after dialysis or an additional dosage to be administered.

How to manage the interaction:
Duocin 250 mg Tablet serum levels may be decreased by hemodialysis and peritoneal dialysis. Supplemental doses should be given at the end of each hemodialysis session.
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESConvulsions, not elsewhere classified
Moderate
How does the disease interact with Duocin 250 mg Tablet:
seizure disorders: In some patients, seizures were reported with whom renal dysfunction which incase of dosage adjustment was not done. Discontinue Duocin 250 mg Tablet if seizures are reported.

How to manage the interaction:
Cephalosporin antibiotics may trigger seizures. Duocin 250 mg Tablet should be discontinued if seizures associated with drug therapy occur.
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESOther diseases of liver
Moderate
How does the disease interact with Duocin 250 mg Tablet:
liver disease: With Duocin 250 mg Tablet, a transient increase in the AST, ALT, and alkaline phosphatase levels was observed. Use with caution and closely monitor for hepatic function is recommended.

How to manage the interaction:
Caution and monitoring is recommended in patients with liver disease as cases of hepatitis have been reported with the use of certain cephalosporins.
CEFUROXIME-250MG+LACTOBACILLUS-120MILLION SPORESOther diseases of liver
Moderate
How does the disease interact with Duocin 250 mg Tablet:
Rarely, cephalosporins use may cause hypoprothrombinemia, with or without bleeding. Monitor for Prothrombin time.

How to manage the interaction:
Cephalosporins may be associated with reduced prothrombin activity/prolonged prothrombin time (blood takes too long to form a clot). Prothrombin time should be monitored in at-risk patients and managed as needed.

FAQs

Duocin 250 mg Tablet contains Cefuroxime and Lactobacillus. Cefuroxime is an antibiotic that works by interfering with the formation of the bacterial cell wall (a protective covering) that is necessary for their survival. It damages the bacterial cell wall and kills bacteria. Lactobacillus is a probiotic (a live microorganism that keeps the body healthy) that helps to restore good bacteria in the intestines. Thus, it prevents diarrhoea and loss of beneficial bacteria due to the prolonged intake of antibiotics.

Duocin 250 mg Tablet is not used to treat viral infections. Duocin 250 mg Tablet is an antibiotic that is used to treat only bacterial infections.

Do not stop taking Duocin 250 mg Tablet and complete the full course of medication even if you feel better. Your symptoms may get better before the infection is totally cured.

Take Duocin 250 mg Tablet as soon you remember it. Do not take it if it's nearly time for your next dose. Also, do not take an additional dose to make up for your missed dose.

Drug-Drug Interactions Checker List

  • AMIKACIN
  • CHLORAMPHENICOL
  • ETHINYLESTRADIOL
  • FUROSEMIDE
  • CHOLERA VACCINE

Special Advise

You are recommended to complete the full course with Duocin 250 mg Tablet as prescribed by your doctor for effective results.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and causes infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes: spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Some common symptoms of bacterial infection include cough, fever, and tiredness.

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