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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
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Composition :

ELTROMBOPAG-50MG

Manufacturer/Marketer :

Glenmark Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Eltrog 50 Tablet

Eltrog 50 Tablet belongs to the class of 'platelet-stimulating agents' primarily used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Eltrog 50 Tablet is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused due to hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Eltrog 50 Tablet contains 'Eltrombopag' which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet's production. Eltrog 50 Tablet works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Eltrog 50 Tablet helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Take Eltrog 50 Tablet as prescribed by your doctor. In some cases, Eltrog 50 Tablet can cause common side effects like nausea, diarrhoea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. These side effects are not familiar to everyone who take Eltrog 50 Tablet and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Eltrog 50 Tablet or any other medicines, before starting Eltrog 50 Tablet. It is essential to inform your doctor if you have any heart, kidney or liver problems, blood disorders, blood clotting problems and cataracts before starting Eltrog 50 Tablet. It is advised to consult the doctor if you are pregnant or planning to conceive. Eltrog 50 Tablet is not indicated for use in breastfeeding since it passes into the breast milk. Eltrog 50 Tablet may make you dizzy, hence drive or operate machinery only when you are mentally alert. 

Uses of Eltrog 50 Tablet

Low platelet count and Severe aplastic anaemia (SAA).

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Take it on an empty stomach as prescribed by the doctor. Do not crush, chew or break it. Oral suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Powder: Mix the powder with the prescribed amount of water. Take it with or without food with an oral syringe in the dose and duration prescribed by the doctor.

Medicinal Benefits

Eltrog 50 Tablet contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults. Eltrog 50 Tablet works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets. The increase in these bone marrow cells stimulates the production of platelets. Thus Eltrog 50 Tablet prevents bleeding episodes by increasing the number of platelets in the blood.

Storage

Store in a cool and dry place away from sunlight
Side effects of Eltrog 50 Tablet
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the steps to manage Joint Pain caused by medication usage:
  • Please inform your doctor about joint pain symptoms, as they may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Your doctor may prescribe common pain relievers if necessary to treat joint discomfort.
  • Maintaining a healthy lifestyle is key to relieving joint discomfort. Regular exercise, such as low-impact sports like walking, cycling, or swimming, should be combined with a well-balanced diet. Aim for 7-8 hours of sleep per night to assist your body in repairing and rebuilding tissue.
  • Applying heat or cold packs to the affected joint can help reduce pain and inflammation.
  • Please track when joint pain occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If your joint pain is severe or prolonged, consult a doctor to rule out any underlying disorders that may require treatment.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.

Drug Warnings

If you are known to be allergic to Eltrog 50 Tablet or other medicines, please inform your doctor in advance. Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Eltrog 50 Tablet. Take Eltrog 50 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Eltrog 50 Tablet. Eltrog 50 Tablet is not recommended during pregnancy since it may have harmful effects on the foetus. Consult your doctor before using Eltrog 50 Tablet if you are a breastfeeding mother. Do not drive or operate machinery since Eltrog 50 Tablet may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive. Avoid or limit alcohol consumption with Eltrog 50 Tablet as it may affect the efficacy of Eltrog 50 Tablet. Eltrog 50 Tablet is not recommended for children less than one year of age in ITP and children less than two years of age in SAA. 

Drug-Drug Interactions

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EltrombopagCalcium chloride
Critical
EltrombopagMagnesium oxide
Critical

Drug-Drug Interactions

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EltrombopagCalcium chloride
Critical
How does the drug interact with Eltrog 50 Tablet:
When Eltrog 50 Tablet is mixed with Calcium chloride, the amount of Eltrog 50 Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Eltrog 50 Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagMagnesium oxide
Critical
How does the drug interact with Eltrog 50 Tablet:
Coadministration of Magnesium oxide with Eltrog 50 Tablet can impair the absorption of Eltrog 50 Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Eltrog 50 Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagMagnesium citrate
Critical
How does the drug interact with Eltrog 50 Tablet:
Taking magnesium citrate with Eltrog 50 Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Eltrog 50 Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Eltrog 50 Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
EltrombopagAluminium hydroxide
Critical
How does the drug interact with Eltrog 50 Tablet:
Coadministration of Eltrog 50 Tablet and aluminum hydroxide may interfere with the absorption of Eltrog 50 Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Eltrog 50 Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EltrombopagFerrous gluconate
Critical
How does the drug interact with Eltrog 50 Tablet:
Ferrous gluconate can make Eltrog 50 Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Eltrog 50 Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Eltrog 50 Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagFerric maltol
Critical
How does the drug interact with Eltrog 50 Tablet:
Ferric maltol can make Eltrog 50 Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Eltrog 50 Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Eltrog 50 Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagInterferon alfa-2a
Severe
How does the drug interact with Eltrog 50 Tablet:
Coadministration of Eltrog 50 Tablet with Interferon alfa-2a can increase the risk or severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Eltrog 50 Tablet and Interferon alfa-2a, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
EltrombopagPeginterferon alfa-2a
Severe
How does the drug interact with Eltrog 50 Tablet:
Combining Eltrog 50 Tablet with Peginterferon alfa-2a can lower the metabolism of Eltrog 50 Tablet. This can increase the risk or severity of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Eltrog 50 Tablet and Peginterferon alfa-2a, but it can be taken if prescribed by a doctor. If you have any of these symptoms like confusion, changes in consciousness, harmful substances in the blood, bleeding from enlarged veins, bleeding, infection of the abdominal wall, complications, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, feeling tired, feeling sick, throwing up, bleeding, pain, dark urine, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagThalidomide
Severe
How does the drug interact with Eltrog 50 Tablet:
Taking thalidomide together with Eltrog 50 Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Eltrog 50 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EltrombopagCalcium gluconate
Severe
How does the drug interact with Eltrog 50 Tablet:
Co-administration of Eltrog 50 Tablet and Calcium gluconate may interfere with the absorption of Eltrog 50 Tablet and reduce its effectiveness.

How to manage the interaction:
Although there is an interaction, Calcium gluconate can be taken with Eltrog 50 Tablet if prescribed by the doctor. However, take Eltrog 50 Tablet on an empty stomach, i.e., 2 hours before or 4 hours after taking calcium gluconate. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • High protein diet such as lean meat, chicken, crab, turkey, beef and fish can help increase the platelet count.
  • Eating Papaya is the best natural remedy to increase your platelet count, you can also use papaya leave's mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Habit Forming

No

Therapeutic Class

PLATELET STIMULATING AGENTS

Eltrog 50 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Eltrog 50 Tablet contains Eltrombopag that stimulates platelet's production (helps in clotting) from megakaryocytes (bone marrow cells). Thus Eltrog 50 Tablet lowers the risk of bleeding episodes in diseases like immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA).

Do not stop using Eltrog 50 Tablet even if you feel better. It should be strictly used as advised by your doctor to avoid the recurrence of symptoms and worsening of the disease.

Eltrog 50 Tablet should be used with caution and only under doctor's supervision in cases of any allergic reactions, blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases.

Eltrog 50 Tablet decreases the risk of bleeding by increasing the platelet count in your body. However, you are advised to stay away from activities that may increase your risk of bleeding like contact sports and using sharp objects like razors and nail cutters.

It is advised to take Eltrog 50 Tablet on an empty stomach. Please take Eltrog 50 Tablet at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Eltrog 50 Tablet.

Drug-Drug Interactions Checker List

  • METHOTREXATE
  • TOPOTECAN
  • CICLOSPORIN
  • AZATHIOPRINE
  • LOPINAVIR
  • RITONAVIR
  • DANAZOL
  • IRON
  • CALCIUM
  • ZINC+ZINC GLUCONATE

Special Advise

  • Keep a check on your daily blood pressure and blood sugar levels and if you notice any fluctuations, please consult a doctor.
  • Since Eltrog 50 Tablet affects liver enzymes, your doctor may suggest liver function tests to check your aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin levels before starting treatment and every two weeks after the treatment with Eltrog 50 Tablet.
  • Eltrog 50 Tablet may also interfere with creatinine and bilirubin lab tests, hence, please inform your doctor and laboratory staff in advance.

Disease/Condition Glossary

Immune (idiopathic) thrombocytopenic purpura (ITP): It is an immune condition associated with low levels of platelets, and the blood doesn't clot normally. It occurs when the immune system mistakenly attacks its own platelets. ITP also occurs in children, followed by a viral infection. Symptoms of ITP may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow and pinpoint-sized reddish-purple spots on the lower legs.

Hepatitis C: It is an infection and inflammation of the liver caused due to hepatitis C virus. This virus can cause both acute and chronic hepatitis. Acute hepatitis C is a short term illness that may range for six months. Chronic hepatitis C is a long-lasting disease that may lead to other severe liver cancer problems or cirrhosis (inflammation of the liver). Symptoms of hepatitis C include fatigue, nausea, loss of appetite and yellowing of the eyes and skin.

Severe aplastic anaemia (SAA): Aplastic anaemia is also called bone marrow aplasia. It is a condition in which the bone marrow doesn't make enough blood cells. SAA is commonly caused due to the damage of bone marrow. This damage can be a congenital disability or may occur because of radiation, chemotherapy, toxic chemicals, certain drugs and infections. Symptoms of SAA include fatigue, frequent infections, rapid heart rate and bleeding. 

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