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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Composition

ELTROMBOPAG-50MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Trombopag 50 Tablet 7's

Trombopag 50 Tablet 7's belongs to the class of 'platelet-stimulating agents' primarily used to treat low blood platelet count in patients with idiopathic thrombocytopenic purpura (ITP) and hepatitis C virus (HCV) infections. Trombopag 50 Tablet 7's is also used to treat severe aplastic anaemia (SAA) in adults. Idiopathic thrombocytopenic purpura is an immune condition associated with low levels of platelets. Hepatitis C is an infection and inflammation of the liver caused due to hepatitis C virus. Severe aplastic anaemia is a condition in which the bone marrow doesn't make enough blood cells.

Trombopag 50 Tablet 7's contains 'Eltrombopag' which belongs to the class of 'thrombopoietin receptor agonists'. Thrombopoietin is a glycoprotein hormone that stimulates the formation of megakaryocytes (large bone marrow cells) and further regulates platelet's production. Trombopag 50 Tablet 7's works by increasing these large bone marrow cells responsible for the production of platelets. Thus, Trombopag 50 Tablet 7's helps increase these bone marrow cells, thereby stimulating the number of platelets, which further lowers the risk of bleeding.

Take Trombopag 50 Tablet 7's as prescribed by your doctor. In some cases, Trombopag 50 Tablet 7's can cause common side effects like nausea, diarrhoea, headache, muscle pain, tiredness, loss of appetite, fever, anaemia (lack of blood cells), cough and tingling numbness. These side effects are not familiar to everyone who take Trombopag 50 Tablet 7's and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Let your doctor know if you have any allergic reactions to Trombopag 50 Tablet 7's or any other medicines, before starting Trombopag 50 Tablet 7's. It is essential to inform your doctor if you have any heart, kidney or liver problems, blood disorders, blood clotting problems and cataracts before starting Trombopag 50 Tablet 7's. It is advised to consult the doctor if you are pregnant or planning to conceive. Trombopag 50 Tablet 7's is not indicated for use in breastfeeding since it passes into the breast milk. Trombopag 50 Tablet 7's may make you dizzy, hence drive or operate machinery only when you are mentally alert. 

Uses of Trombopag 50 Tablet 7's

Low platelet count and Severe aplastic anaemia (SAA).

Directions for Use

Tablet: Swallow it as a whole with a glass of water. Take it on an empty stomach as prescribed by the doctor. Do not crush, chew or break it. Oral suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.Powder: Mix the powder with the prescribed amount of water. Take it with or without food with an oral syringe in the dose and duration prescribed by the doctor.

Medicinal Benefits

Trombopag 50 Tablet 7's contains 'Eltrombopag,' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune (idiopathic) thrombocytopenic purpura (ITP), hepatitis C virus (HCV) infections and severe aplastic anaemia (SAA) in adults. Trombopag 50 Tablet 7's works by increasing megakaryocytes, the large bone marrow cells responsible for the production of platelets. The increase in these bone marrow cells stimulates the production of platelets. Thus Trombopag 50 Tablet 7's prevents bleeding episodes by increasing the number of platelets in the blood.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trombopag 50 Tablet 7's

  • Nausea
  • Diarrhoea
  • Headache
  • Muscle pain
  • Tiredness
  • Loss of appetite
  • Fever
  • Anaemia (lack of blood cells)
  • Cough
  • Tingling or numbness 

Drug Warnings

If you are known to be allergic to Trombopag 50 Tablet 7's or other medicines, please inform your doctor in advance. Brief your medical history if you have blood clots, clotting disorders (Factor V Leiden), blood disorders like blood cancer, myelodysplastic syndrome, cataracts, liver or kidney diseases before starting Trombopag 50 Tablet 7's. Take Trombopag 50 Tablet 7's at least two hours before or four hours after consuming antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminium, selenium and zinc), dairy products, calcium-enriched foods and fortified juices since they interfere with the absorption of Trombopag 50 Tablet 7's. Trombopag 50 Tablet 7's is not recommended during pregnancy since it may have harmful effects on the foetus. Consult your doctor before using Trombopag 50 Tablet 7's if you are a breastfeeding mother. Do not drive or operate machinery since Trombopag 50 Tablet 7's may cause side effects like dizziness and tiredness, affecting your ability to concentrate and drive. Avoid or limit alcohol consumption with Trombopag 50 Tablet 7's as it may affect the efficacy of Trombopag 50 Tablet 7's. Trombopag 50 Tablet 7's is not recommended for children less than one year of age in ITP and children less than two years of age in SAA. 

Drug-Drug Interactions

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EltrombopagMagnesium citrate
Critical
EltrombopagFerric maltol
Critical

Drug-Drug Interactions

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EltrombopagMagnesium citrate
Critical
How does the drug interact with Trombopag 50 Tablet:
Taking magnesium citrate with Trombopag 50 Tablet can make it less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Taking Magnesium citrate with Trombopag 50 Tablet is not recommended as it can result in an interaction. It can be taken if your doctor has advised it. You should take Trombopag 50 Tablet on an empty stomach at least 2 hours before or 4 hours after magnesium citrate. Do not discontinue any medication without consulting a doctor.
EltrombopagFerric maltol
Critical
How does the drug interact with Trombopag 50 Tablet:
Ferric maltol can make Trombopag 50 Tablet less effective by reducing its absorption and lowering its concentration in the blood. This can lead to poor treatment outcomes.

How to manage the interaction:
Taking Ferric maltol with Trombopag 50 Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Trombopag 50 Tablet on an empty stomach at least 2 hours before or 4 hours after ferric maltol. Do not discontinue any medication without consulting a doctor.
EltrombopagFerrous gluconate
Critical
How does the drug interact with Trombopag 50 Tablet:
Ferrous gluconate can make Trombopag 50 Tablet less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Trombopag 50 Tablet with Ferrous gluconate is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. You should take Trombopag 50 Tablet on an empty stomach at least 2 hours before or 4 hours after ferrous gluconate. Do not discontinue any medication without consulting a doctor.
EltrombopagAluminium hydroxide
Critical
How does the drug interact with Trombopag 50 Tablet:
Coadministration of Trombopag 50 Tablet and aluminum hydroxide may interfere with the absorption of Trombopag 50 Tablet and reduce its effectiveness.

How to manage the interaction:
Taking Trombopag 50 Tablet with aluminum hydroxide is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.
EltrombopagCalcium chloride
Critical
How does the drug interact with Trombopag 50 Tablet:
When Trombopag 50 Tablet is mixed with Calcium chloride, the amount of Trombopag 50 Tablet in the blood can decrease. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Trombopag 50 Tablet with calcium chloride is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
EltrombopagMagnesium oxide
Critical
How does the drug interact with Trombopag 50 Tablet:
Coadministration of Magnesium oxide with Trombopag 50 Tablet can impair the absorption of Trombopag 50 Tablet which leads to increased levels in the blood. This can increase the risk and severity of side effects.

How to manage the interaction:
Taking Magnesium oxide with Trombopag 50 Tablet together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any body aches or pain, chills, cough, difficulty in breathing, fever, headache, or loss of voice you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EltrombopagPeginterferon alfa-2a
Severe
How does the drug interact with Trombopag 50 Tablet:
Combining Trombopag 50 Tablet with Peginterferon alfa-2a can lower the metabolism of Trombopag 50 Tablet. This can increase the risk or severity of liver damage.

How to manage the interaction:
There may be a possibility of interaction between Trombopag 50 Tablet and Peginterferon alfa-2a, but it can be taken if prescribed by a doctor. If you have any of these symptoms like confusion, changes in consciousness, harmful substances in the blood, bleeding from enlarged veins, bleeding, infection of the abdominal wall, complications, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, feeling tired, feeling sick, throwing up, bleeding, pain, dark urine, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
EltrombopagInterferon alfa-2a
Severe
How does the drug interact with Trombopag 50 Tablet:
Coadministration of Trombopag 50 Tablet with Interferon alfa-2a can increase the risk or severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Trombopag 50 Tablet and Interferon alfa-2a, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, it's important to call a doctor right away. Do not stop using any medications without talking to a doctor.
EltrombopagInterferon alfa-2b
Severe
How does the drug interact with Trombopag 50 Tablet:
When Interferon alfa-2b is taken with Trombopag 50 Tablet, it can lower the metabolism of Trombopag 50 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Trombopag 50 Tablet and Interferon alfa-2b, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to call a doctor right away. These symptoms include chronic hepatitis C, advanced liver disease, cirrhosis, liver failure, and other liver-related problems. You should also seek medical attention if you experience confusion, fever, joint pain, swelling, or any other unusual symptoms. Do not discontinue any medications without consulting a doctor.
EltrombopagThalidomide
Severe
How does the drug interact with Trombopag 50 Tablet:
Taking thalidomide together with Trombopag 50 Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Trombopag 50 Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat natural and healthy foods by cutting down on fatty and sodium processed foods.
  • Exercise regularly to maintain good health.
  • Avoid smoking and alcohol intake.
  • Avoid activities like contact sports and use sharp objects like nail cutters and razors to decrease bleeding risk.
  • High protein diet such as lean meat, chicken, crab, turkey, beef and fish can help increase the platelet count.
  • Eating Papaya is the best natural remedy to increase your platelet count, you can also use papaya leave's mixture.
  • Include iron-rich foods like pomegranate, beetroot, green leafy vegetables, carrots, raisins, oranges, peanuts, kidney beans, and black-eyed peas in your diet.
  • Vitamin C sources like guava, black currant, red pepper, kiwi, green peppers, orange, strawberries, pineapple, peas, mango, grapefruit and broccoli can also boost your platelet count.

Habit Forming

No

Therapeutic Class

PLATELET STIMULATING AGENTS

Trombopag 50 Tablet 7's Substitute

Substitutes safety advice
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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

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  • CALCIUM
  • ZINC+ZINC GLUCONATE

Special Advise

  • Keep a check on your daily blood pressure and blood sugar levels and if you notice any fluctuations, please consult a doctor.
  • Since Trombopag 50 Tablet 7's affects liver enzymes, your doctor may suggest liver function tests to check your aspartate aminotransferase (AST), alanine aminotransferase (ALT) and bilirubin levels before starting treatment and every two weeks after the treatment with Trombopag 50 Tablet 7's.
  • Trombopag 50 Tablet 7's may also interfere with creatinine and bilirubin lab tests, hence, please inform your doctor and laboratory staff in advance.

Disease/Condition Glossary

Immune (idiopathic) thrombocytopenic purpura (ITP): It is an immune condition associated with low levels of platelets, and the blood doesn't clot normally. It occurs when the immune system mistakenly attacks its own platelets. ITP also occurs in children, followed by a viral infection. Symptoms of ITP may include easy bruising, bleeding from gums and nose, blood in urine and stools, heavy menstrual flow and pinpoint-sized reddish-purple spots on the lower legs.

Hepatitis C: It is an infection and inflammation of the liver caused due to hepatitis C virus. This virus can cause both acute and chronic hepatitis. Acute hepatitis C is a short term illness that may range for six months. Chronic hepatitis C is a long-lasting disease that may lead to other severe liver cancer problems or cirrhosis (inflammation of the liver). Symptoms of hepatitis C include fatigue, nausea, loss of appetite and yellowing of the eyes and skin.

Severe aplastic anaemia (SAA): Aplastic anaemia is also called bone marrow aplasia. It is a condition in which the bone marrow doesn't make enough blood cells. SAA is commonly caused due to the damage of bone marrow. This damage can be a congenital disability or may occur because of radiation, chemotherapy, toxic chemicals, certain drugs and infections. Symptoms of SAA include fatigue, frequent infections, rapid heart rate and bleeding. 

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