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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

GABAPENTIN-400MG

Manufacturer/Marketer :

East West Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Encentin-400mg Tablet

Encentin-400mg Tablet belongs to a group of medications called anticonvulsants used to manage or prevent neuropathic pain and epilepsy. Besides this, occasionally used to treat migraine headaches. Neuropathic pain is a chronic progressive nerve disease that causes nerve pain. On the other hand, epilepsy is a nervous system disorder that occurs due to disturbed nerve cell activity in the brain.

Encentin-400mg Tablet contains Gabapentin' which works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. Besides this, it also decreases the number of pain signals sent out by damaged nerves in the body.

Encentin-400mg Tablet is available on prescription. It comes as capsules, tablets, and a liquid that you drink. Encentin-400mg Tablet can be taken by adults and children aged six years and over. Take Encentin-400mg Tablet exactly as directed. Please do not take more or less of it or take it more often than prescribed by your doctor. Sometimes, you may experience some side effects, including feeling sleepy, tired and dizzy. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking Encentin-400mg Tablet for as long as your doctor has prescribed. Please do not stop taking Encentin-400mg Tablet without consulting your doctor as it could cause withdrawal symptoms. Do not take Encentin-400mg Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Encentin-400mg Tablet may cause drowsiness and dizziness, so drive if you are alert. Encentin-400mg Tablet should not be given to children unless prescribed. Avoid consuming alcohol along with Encentin-400mg Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed of your health condition and medicines to rule out any side effects.

Uses of Encentin-400mg Tablet

Neuropathic pain, Epilepsy.

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush, break or chew it.Oral Solution/Suspension: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup provided by the pack.

Medicinal Benefits

Encentin-400mg Tablet belongs to a class of medications called 'anticonvulsants' used to prevent neuropathic pain (pain due to damaged nerves), fibromyalgia (musculoskeletal pain), and epilepsy (fits). It works by binding to the specific site on voltage-gated calcium channels and blocking the action of overexcited channels; this helps in relieving nerve pain and lowers the risk of seizures. Overall it reduces nerve pain by interfering with pain signals travelling through the damaged nerves and the brain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Encentin-400mg Tablet if you are allergic to any of its contents. Inform your doctor before taking Encentin-400mg Tablet if you have symptoms of suicidal ideation or behaviour, drug addiction, chronic pulmonary insufficiency, muscle weakness, heart problems, liver/kidney impairment. Please do not stop taking Encentin-400mg Tablet without consulting your doctor as it could cause withdrawal symptoms. Do not take Encentin-400mg Tablet if you are pregnant or breastfeeding unless prescribed by the doctor. Avoid driving and consuming alcohol along with Encentin-400mg Tablet it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Avoid taking St John's Wort herbal supplement (antidepressant) while taking Encentin-400mg Tablet as it might cause increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Encentin-400mg Tablet:
Co-administration of Buprenorphine and Encentin-400mg Tablet may cause central nervous system depression and lead to serious side effects (respiratory distress -build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Encentin-400mg Tablet and Buprenorphine, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Encentin-400mg Tablet:
Taking fentanyl with other drugs that cause central nervous system depression, such as Encentin-400mg Tablet, might result in an increased risk of adverse effects.

How to manage the interaction:
Although combining Fentanyl and Encentin-400mg Tablet may cause an interaction, they can be used if advised by your doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, or confusion. If you have any of the above symptoms, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Encentin-400mg Tablet:
Co-administration of Tramadol with Encentin-400mg Tablet may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Encentin-400mg Tablet and Tramadol, you can take these medicines together if prescribed by your doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult your doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Encentin-400mg Tablet:
Co-administration of Butorphanol and Encentin-400mg Tablet may cause central nervous system depression and lead to serious side effects such as respiratory distress (build-up of fluid in the air sacs of the lungs).

How to manage the interaction:
Although there is a possible interaction between Encentin-400mg Tablet and Butorphanol, you can take these medicines together if prescribed by a doctor. However, if you experience shortness of breath, fast heart rate, fast breathing, extreme tiredness, fever, cough with phlegm, or shallow breaths, please consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Encentin-400mg Tablet:
Using Ketamine together with Encentin-400mg Tablet may increase side effects.

How to manage the interaction:
Although taking Ketamine and Encentin-400mg Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you start feeling dizzy, tired, confused, have trouble focusing, feel very sleepy, or have trouble breathing, make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Encentin-400mg Tablet:
Taking Pentazocine with Encentin-400mg Tablet can increase the risk of serious side effects.

How to manage the interaction:
Although taking Pentazocine and Encentin-400mg Tablet together can evidently cause an interaction, but it can be taken if a doctor has suggested it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment contact a doctor immediately. Do not stop using any medications without talking to a doctor.
GabapentinEsketamine
Severe
How does the drug interact with Encentin-400mg Tablet:
Combining Encentin-400mg Tablet with Esketamine can increase the risk of side effects.

How to manage the interaction:
Although taking Encentin-400mg Tablet and Esketamine together can evidently cause an interaction, it can be taken if a doctor has suggested it. Consult a doctor if you experience any symptoms such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination. Do not stop using any medications without a doctor's advice.
GabapentinRemifentanil
Severe
How does the drug interact with Encentin-400mg Tablet:
Combining Remifentanil with Encentin-400mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Encentin-400mg Tablet with Remifentanil together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GabapentinPethidine
Severe
How does the drug interact with Encentin-400mg Tablet:
Combining Meperidine with Encentin-400mg Tablet can increase the risk of CNS depression.

How to manage the interaction:
Co-administration of Pethidine with Encentin-400mg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
GabapentinHydrocodone
Severe
How does the drug interact with Encentin-400mg Tablet:
When Hydrocodone is taken with Encentin-400mg Tablet, the amount of Hydrocodone in the blood may be reduced.

How to manage the interaction:
Although there is a possible interaction between Encentin-400mg Tablet and Hydrocodone, you can take these medicines together if prescribed by a doctor. If you notice any symptoms like trouble breathing, dizziness, or trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain.
  • Rest well, get plenty of sleep.
  • Try to take a warm bath as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Using essential oils for massages can help increase circulation.
  • Acupuncture can be helpful by stimulating pressure points.
  • Meditation and yoga can help lower stress, decrease pain sensitivity, and improves coping skills.

Habit Forming

Yes

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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GABAPENTIN-400MGPersons encountering health services for other counselling and medical advice, not elsewhere classified
Severe
GABAPENTIN-400MGUnspecified kidney failure
Severe

Drug-Diseases Interactions

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GABAPENTIN-400MGPersons encountering health services for other counselling and medical advice, not elsewhere classified
Severe
How does the disease interact with Encentin-400mg Tablet:
Agents that are hypnotic, sedative, or anxiolytic have the potential to lead to dependence and abuse. Particularly after continuous usage of large dosages, tolerance and physical and psychological dependence can develop, and abrupt termination and/or a dosage reduction may hasten withdrawal symptoms. Overdosage can still result in respiratory depression and mortality in those who have built up a tolerance to it. It is best to use anxiolytic, sedative, and hypnotic medications sparingly and for the shortest amount of time possible during therapy. When receiving treatment with these medications, addicts, such as those with a history of alcohol or drug misuse, should be closely monitored or under medical supervision. Additionally, it might be a good idea to avoid giving these people huge doses of medication. if dependence develops with repeated use or

How to manage the interaction:
Encentin-400mg Tablet should be used with caution. Addiction-prone individuals, such as those with a history of alcohol or substance abuse, should be under careful surveillance or medical supervision when treated with Encentin-400mg Tablet. After prolonged use or if dependency is suspected, please consult your doctor as withdrawal of medication should be gradual.
GABAPENTIN-400MGUnspecified kidney failure
Severe
How does the disease interact with Encentin-400mg Tablet:
The kidney is the main organ used to remove Encentin-400mg Tablet in its unaltered form. Patients with poor renal function should receive Encentin-400mg Tablet therapy with caution. Dosage adjustments and titration should be made in accordance with product package labeling and individual patient response

How to manage the interaction:
Encentin-400mg Tablet should be used with caution in patients with impaired kidney function.
GABAPENTIN-400MGCare involving dialysis
Moderate
How does the disease interact with Encentin-400mg Tablet:
Encentin-400mg Tablet is removed by hemodialysis and should be administered after dialysis.

How to manage the interaction:
Encentin-400mg Tablet is removed by hemodialysis. Therefore, it should be administered after dialysis.

FAQs

Drug-Drug Interactions Checker List

  • MORPHINE
  • HYDROCODONE
  • OXYCODONE
  • TRAMADOL
  • CODEINE
  • FLUOXETINE
  • AMITRIPTYLINE
  • QUETIAPINE
  • MEFLOQUINE
  • ORLISTAT
  • DIPHENHYDRAMINE
  • CETIRIZINE

Special Advise

  • Do not take Encentin-400mg Tablet for a prolonged time; it may lead to mental or physical dependence on Encentin-400mg Tablet .
  • If you are taking any antacids containing aluminium or magnesium, try to keep at least 2 hours gap between the intake of Encentin-400mg Tablet and these antacids to avoid drug-drug interaction.
  • Encentin-400mg Tablet can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position.
  • Encentin-400mg Tablet can cause dry mouth, so in that case, drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Disease/Condition Glossary

Neuropathic Pain: It is a nervous disorder that occurs due to nerve damage caused by chronic progressive nerve disease, limb amputation, diabetes, or infection or injury. The pain could be intermittent or continuous, felt as a prickling, stabbing, tingling, or burning sensation. A feeling of numbness and loss of senses is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain that is not triggered by an injury, the body sends the pain signals. Symptoms include untriggered pain, unpleasant feeling, shooting, burning, or stabbing pain, difficulty resting or sleeping, pain caused by events that are usually not painful.

Epilepsy: is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury, or stroke.

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