Endoblock T Kit Combipack
MRP ₹2267
(Inclusive of all Taxes)
₹340.1 Cashback (15%)
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About Endoblock T Kit Combipack
Endoblock T Kit Combipack belongs to the class of medicines called antihypertensives, primarily used to treat pulmonary arterial hypertension (high blood pressure affecting arteries in the lungs). Pulmonary hypertension is defined as high blood pressure in the blood veins that supply the blood to the lungs (pulmonary arteries). It can affect the arteries of the lungs and the right side of the heart. The common symptoms of pulmonary hypertension are shortness of breath, dizziness, palpitations, and chest pressure.
Endoblock T Kit Combipack is a combination of two medications: ambrisentan and tadalafil. Tadalafil belongs to a class of drugs known as phosphodiesterase-5 (PDE5) inhibitors. It aids in treating pulmonary hypertension by relaxing blood vessels in the chest. This increases blood supply to the lungs while decreasing the workload on the heart. Ambrisentan belongs to a class of drugs known as 'endothelin receptor antagonists.' Ambrisentan prevents endothelin, a naturally occurring substance that constricts blood vessels and raises blood pressure. It relaxes the constricted pulmonary arteries and increases blood supply to the lungs, lowering blood pressure.
Endoblock T Kit Combipack can be taken with or without food. Swallow the tablet whole with a glass of water; do not crush, chew or break it. You are advised to take Endoblock T Kit Combipack for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Endoblock T Kit Combipack can cause side effects like headache, flushing, blocked nose, palpitations, diarrhoea, nausea, indigestion, muscle aches and pain. These side effects are unfamiliar to everyone and vary from person to person. Please get in touch with your doctor if you experience any of the side effects persistently.
If you are allergic to any of the ingredients of Endoblock T Kit Combipack, please do not take it. Stopping Endoblock T Kit Combipack without consulting your doctor may aggravate your condition and increase your chances of future cardiac problems. Consult your doctor if you are pregnant or breastfeeding. Endoblock T Kit Combipack causes drowsiness and dizziness, so drive only if you are alert. Endoblock T Kit Combipack should not be given to children as safety and effectiveness have not been established. Alcohol should not be consumed with Endoblock T Kit Combipack since it may raise the risk of low blood pressure. Keep your doctor up to date on your medical condition and medications to rule out any potential side effects.
Uses of Endoblock T Kit Combipack
Directions for Use
Key Benefits
Endoblock T Kit Combipack is an antihypertensive drug used to treat pulmonary arterial hypertension (PAH). Endoblock T Kit Combipack contains tadalafil (PDE-5 inhibitor) and ambrisentan (endothelin receptor antagonist). Tadalafil aids in treating pulmonary hypertension by relaxing blood vessels in the chest. This increases blood supply to the lungs while decreasing the workload on the heart. Ambrisentan prevents endothelin, a naturally occurring substance that constricts blood vessels and raises blood pressure. It relaxes the constricted pulmonary arteries and increases blood supply to the lungs, lowering blood pressure.
Storage
- Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
- Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
- Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
- Gently massage the swollen area with firm but not painful pressure.
- Keep the swollen area clean and moisturized to prevent injury and infection.
- Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
- If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
- A blocked nose can be relieved by drinking more water, which helps clear fluids.
- Use saline nasal spray available over the counter to relieve blockage or blow harder to remove the mucus.
- Use nasal strips that can be placed on the nose to widen nostrils and increase airflow.
- Keep a humidifier around to moisten air at home/workplace.
- Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
- Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
- Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
- Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
- Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
- Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
- Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
- Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
- Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
- Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
- Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
- Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Drug Warnings
If you are allergic to any of the ingredients of Endoblock T Kit Combipack, please do not take it. Stopping Endoblock T Kit Combipack without consulting your doctor may aggravate your condition and increase your chances of future cardiac problems. Endoblock T Kit Combipack is not recommended during pregnancy because it is harmful to the foetus. Before using Endoblock T Kit Combipack, you should definitely get a negative pregnancy test. Also, if you are undergoing treatment with Endoblock T Kit Combipack, please use reliable forms of birth control to avoid pregnancy. Brief your medical history to the doctor if you have heart failure, liver or kidney diseases, lung conditions (pulmonary fibrosis), anaemia, oedema (fluid retention) and hypotension (low blood pressure). Endoblock T Kit Combipack causes drowsiness and dizziness, so drive if you are alert. Avoid consuming alcohol with Endoblock T Kit Combipack as it may raise the chance of developing low blood pressure. Endoblock T Kit Combipack is not suggested for patients under the age of 18.
Drug-Drug Interactions
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Taking Endoblock T Kit Combipack with Nitroprusside can increase the risk or severity of low blood pressure.
How to manage the interaction:
Taking Endoblock T Kit Combipack with Nitroprusside is generally avoided as it can lead to an interaction, but it can be taken if prescribed by a doctor. If you experience dizziness, or heart palpitations, seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
Taking Endoblock T Kit Combipack with Riociguat may increase the risk or severity of lower the blood pressure.
How to manage the interaction:
Taking Riociguat with Endoblock T Kit Combipack is generally not recommended as it can lead to an interaction, but it can be taken together if prescribed by a doctor. However, if you experience dizziness, headache, and nasal congestion consult a doctor. Do not discontinue any medications without consulting a doctor.
Taking Endoblock T Kit Combipack with Amyl Nitrite can increase the risk or severity of low blood pressure.
How to manage the interaction:
Taking Endoblock T Kit Combipack with Amyl nitrite is generally avoided as it can lead to interaction. They can be taken only when advised by a doctor. Seek immediate medical attention if you experience symptoms like dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Coadministration of Endoblock T Kit Combipack with Isosorbide mononitrate can increase the risk or severity of low blood pressure.
How to manage the interaction:
Taking Isosorbide mononitrate with Endoblock T Kit Combipack is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Taking Endoblock T Kit Combipack with Isosorbide dinitrate can increase the risk or severity of low blood pressure.
How to manage the interaction:
Taking Isosorbide dinitrate with Endoblock T Kit Combipack is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, or heart palpitations. Do not discontinue any medications without consulting a doctor.
When Endoblock T Kit Combipack is taken with cyclosporine, this increases the blood levels of Endoblock T Kit Combipack. This can increase the risk of serious side effects such as liver problems, anemia, and fluid accumulation (particularly in the lungs).
How to manage the interaction:
Co-administration of ciclosporin with Endoblock T Kit Combipack can result in an interaction, but it can be taken if a doctor has advised it. If you experience any of these symptoms such as fever with shivering, pain in your joints, swelling, bleeding or bruising easily, a rash or itchy skin, not feeling hungry, feeling tired, dark color urine, looking pale, dizziness, gaining weight suddenly, or breathing problem, consult a doctor. Do not stop using any medications without talking to a doctor.
Coadministration of Tizanidine with Endoblock T Kit Combipack may increase the risk or severity of developing low blood pressure.
How to manage the interaction:
Although there is a possible interaction between Endoblock T Kit Combipack and Tizanidine, you can take these medicines together if your doctor advises. If you notice any symptoms like headache, dizziness, shortness of breath, chest pain, or sweating, contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Endoblock T Kit Combipack with Mipomersen can increase the risk or severity of liver problems.
How to manage the interaction:
Taking Endoblock T Kit Combipack with Mipomersen together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
Taking Endoblock T Kit Combipack with Lomitapide can lead to or increase the risk or severity of developing liver problems.
How to manage the interaction:
Although there is a possible interaction, Endoblock T Kit Combipack can be taken with Lomitapide if prescribed by the doctor. Consult the prescriber if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
When Endoblock T Kit Combipack and Teriflunomide are taken together, the risk or severity of developing liver injury increases.
How to manage the interaction:
Although taking Endoblock T Kit Combipack and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. If you have any of these symptoms - fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, liver damage, or bleeding - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
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Diet & Lifestyle Advise
- Keep your heart healthy by exercising on a regular basis.
- Consume natural and nutritious foods while avoiding high-sodium processed foods.
- Reduce your salt intake in your diet to keep your blood pressure stable.
- Obesity is a risk factor for hypertension, so reduce those excess pounds.
- Avoid smoking and drinking alcohol.
- High blood pressure can also be caused by chronic stress. As a result, avoid stress and make time for yourself to relax and engage in things that you enjoy.
- Include heart-healthy omega 3 fatty acid-containing foods and beverages in your daily diet.
- To lower your blood pressure (BP), you can also use low-fat cooking oils such as olive oil, coconut oil, soybean oil and canola oil.
Side Effects of Endoblock T Kit Combipack
- Headache
- Flushing (redness of the skin)
- Nasal and sinus congestion (blocked nose)
- Nausea
- Indigestion
- Muscle aches
- Back pain
- Pain in the extremity
- Dizziness
Habit Forming
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Author Details
_0.jpg?tr=q-85,f-webp,w-100,dpr-1,c-at_max "Santoshini Reddy G")
Drug-Diseases Interactions
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FAQs
Endoblock T Kit Combipack contains Ambrisentan and tadalafil. Tadalafil aids in treating pulmonary hypertension by relaxing blood vessels in the chest. This increases blood supply to the lungs while decreasing the workload on the heart. Ambrisentan prevents endothelin, a naturally occurring substance that constricts blood vessels and raises blood pressure. It relaxes the constricted pulmonary arteries and increases blood supply to the lungs, lowering blood pressure.
Yes, Endoblock T Kit Combipack can make you feel dizzy. Dizziness usually occurs when you suddenly stand up from a lying or sitting position. Try rising slowly when you change your posture to relieve dizziness. If the side effect persists longer, please seek medical help.
Even if you feel better, do not stop using Endoblock T Kit Combipack. It should be used exactly as prescribed by your doctor to minimise the recurrence of symptoms and worsening of the disease.
No, it is a medication recommended by a doctor to treat or prevent specific medical issues. Taking it on your own can result in unfavourable side effects.
Endoblock T Kit Combipack is safe if taken in the dose and for the term prescribed by your doctor. Take it exactly as directed and do not miss any doses. Follow your doctor's instructions carefully and notify the doctor if any of the adverse effects bother you.
Endoblock T Kit Combipack should be used with caution if you have any allergic reactions, heart failure, liver or renal disease, lung problems (pulmonary fibrosis), anaemia, oedema (fluid retention), or hypotension (low blood pressure).
It is recommended not to take Endoblock T Kit Combipack along with mediations used to relieve chest pain (nitrates). Please consult your doctor if you have concerns.
Drug-Drug Interactions Checker List
- ILOPROST
- EPOPROSTENOL
- ORGANIC NITRATE
- TAMSULOSIN
- AMLODIPINE
- ENALAPRIL
- METOPROLOL
- ITRACONAZOLE
- RIFAMPICIN
- CYCLOSPORINE
Special Advise
- Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor.
- Your doctor may suggest liver function tests since Endoblock T Kit Combipack may cause a change in liver enzymes.
Disease/Condition Glossary
Pulmonary Arterial Hypertension: It is referred to as high blood pressure in the blood vessels that carry blood from the heart to the lungs (the pulmonary arteries). It can affect the arteries of the lungs and the right side of the heart. The walls of the pulmonary arteries thicken and stiffen, making it difficult for blood to flow through. Because of the reduced blood flow, the right side of the heart has a harder time pumping blood through the arteries. The common symptoms of pulmonary hypertension are shortness of breath, dizziness, palpitations, and chest pressure. It can affect people of all ages, but it's more common in people who already have a heart or lung problem.
Have a query?
Alcohol
Safe if prescribed
It is advised to limit or quit the consumption of alcohol as it may increase the risk of low blood pressure.
Pregnancy
Consult your doctor
Endoblock T Kit Combipack is not recommended in pregnancy. Please consult your doctor if you have any concerns.
Breast Feeding
Consult your doctor
Consult your doctor as there is no substantial research yet on the use of Endoblock T Kit Combipack in breastfeeding/nursing mothers. Endoblock T Kit Combipack should be used in breastfeeding mothers only if the benefits outweigh the risks.
Driving
Safe if prescribed
Endoblock T Kit Combipack causes drowsiness and dizziness, so drive only if you are alert.
Liver
Consult your doctor
Endoblock T Kit Combipack may increase liver enzymes. Before taking Endoblock T Kit Combipack, inform your doctor if you have/had liver illness.
Kidney
Consult your doctor
In cases of renal impairment, take Endoblock T Kit Combipack with caution. If you have kidney problems, you should consult a doctor before beginning Endoblock T Kit Combipack. Your doctor will prescribe if the benefits outweigh the risks.
Children
Safe if prescribed
Safety and effectiveness of Endoblock T Kit Combipack have not been established in patients below 18 years of age.
Recommended for a 30-day course: 2 Packets