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Reviewed By Sunny S , MBBS
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Composition :

ESTRADIOL-2MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Endochrit Tablet

Endochrit Tablet contains a semi-synthetic female hormone Estradiol, indicated for hormonal replacement therapy for treating hypoestrogenism (estrogen deficiency), osteoporosis (thinning of bones) and symptoms associated with menopause (itching, dryness in the vagina, hot flashes). In addition to this, it also helps in preventing osteoporosis. Endochrit Tablet is prescribed when the body is not producing a sufficient amount of natural estrogen.

Endochrit Tablet contains estradiol which regulates the menstrual cycle and ovulation. Endochrit Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause. 

You are advised to take Endochrit Tablet for as long as your doctor has prescribed it for you, depending upon your medical condition. You may experience headache, bloating, hair loss, nausea, breast pain, weight gain, and irregular vaginal bleeding in some cases. Most of these side effects of Endochrit Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have any history of vaginal bleeding, breast cancer, or blood clot in the legs or lungs. If you are pregnant or breastfeeding, please do not take Endochrit Tablet . While taking Endochrit Tablet , your doctor may advise regular tests to monitor its working. Grapefruit juice and St.John’s wort (a natural remedy for depression) should not be taken along with Endochrit Tablet . 

Uses of Endochrit Tablet

Hormonal replacement therapy, Hypoestrogenism (estrogen deficiency), Osteoporosis (thinning of bones), Symptoms associated with menopause (itching, dryness in vagina, hot flushes)

Directions for Use

Swallow Endochrit Tablet as a whole with a glass of water, do not chew or crush it.

Medicinal Benefits

Endochrit Tablet contains a synthetic female hormone that regulates ovulation and menstruation in women. Endochrit Tablet is given as a hormone replacement therapy for estrogen. It is also used in the treatment to relieve symptoms of menopause, such as mood swings, reduced sex drive, hot flashes, night sweats and vaginal dryness. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Endochrit Tablet

  • Headache
  • Bloating
  • Hair loss
  • Nausea
  • Weight gain
  • Breast pain
  • Irregular vaginal bleeding

Drug Warnings

Do not take Endochrit Tablet if you are allergic to any of its ingredients. Inform your doctor if you have breast cancer, vaginal bleeding, blood clot in the leg (deep venous thrombosis), lungs (pulmonary embolism), vein (thrombosis), cancer of the endometrium (womb lining), any blood clotting disorder, recently had a heart attack, liver or kidney disease, porphyria (a group of liver disease), high blood pressure, if you are pregnant or breastfeeding. Avoid smoking as it greatly increases the risk of blood clots, stroke, and heart attack while taking Endochrit Tablet . Grapefruit juice and St. John’s wort (a natural remedy for depression) should not be taken along with Endochrit Tablet . 

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
EstradiolAnastrozole
Severe

Drug-Drug Interactions

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EstradiolBivalirudin
Critical
How does the drug interact with Endochrit Tablet:
When Etodolac is taken with Bivalirudin, the risk or severity of bleeding and haemorrhage increases.

How to manage the interaction:
Taking Bivalirudin with Endochrit Tablet can cause an interaction, consult a doctor before taking it. Do not discontinue any medications without a doctor's advice.
EstradiolAnastrozole
Severe
How does the drug interact with Endochrit Tablet:
Endochrit Tablet may interfere with anastrozole's function and make it less effective in treating your condition.

How to manage the interaction:
Co-administration of Anastrozole with Endochrit Tablet can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolTranexamic acid
Severe
How does the drug interact with Endochrit Tablet:
Co-administration of Endochrit Tablet with Tranexamic acid can increase the risk of blood clots.

How to manage the interaction:
Taking Endochrit Tablet with Tranexamic acid can lead to an interaction; however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolThalidomide
Severe
How does the drug interact with Endochrit Tablet:
Taking thalidomide together with Endochrit Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Endochrit Tablet and thalidomide together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
EstradiolExemestane
Severe
How does the drug interact with Endochrit Tablet:
Using Endochrit Tablet with Exemestane may interfere with Exemestane's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Exemestane and Endochrit Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
EstradiolClindamycin
Severe
How does the drug interact with Endochrit Tablet:
When taken in combination, clindamycin can lower the amount or action of Endochrit Tablet.

How to manage the interaction:
Co-administration of Endochrit Tablet with Clindamycin can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without a doctor's advice.
EstradiolLenalidomide
Severe
How does the drug interact with Endochrit Tablet:
Coadministration of Endochrit Tablet and Lenalidomide can increase the risk of blood clots.

How to manage the interaction:
Although there is an interaction between lenalidomide and Endochrit Tablet, it can be taken if your doctor has advised it. However, if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EstradiolPomalidomide
Severe
How does the drug interact with Endochrit Tablet:
Co-administration of Endochrit Tablet and Pomalidomide can increase the risk of serious blood clots.

How to manage the interaction:
There may be a possibility of interaction between Endochrit Tablet and Pomalidomide, but it can be taken if prescribed by a doctor. However, if you experience symptoms like chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EstradiolLetrozole
Severe
How does the drug interact with Endochrit Tablet:
Letrozole may have a negative effect when used with Endochrit Tablet, making it less effective in treating your disease.

How to manage the interaction:
Although taking Letrozole and Endochrit Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
EstradiolCarfilzomib
Severe
How does the drug interact with Endochrit Tablet:
Carfilzomib can cause serious blood clots and taking it alongside Endochrit Tablet may enhance the risk.

How to manage the interaction:
Co-administration of Endochrit Tablet with Carfilzomib can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness, or swelling in an arm or leg, or numbness or weakness on one side of the body, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ESTRADIOL-2MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
The rate of absorption of oral estrogens may be increased by coadministration with grapefruit juice. Avoid or restrict the consumption of grapefruit juice while taking Endochrit Tablet.

Diet & Lifestyle Advise

  • Do regular exercise and physical activity to minimize hot flashes and improve sleep. Besides this, weight-bearing exercises can help in making your bone strong. Aerobics, yoga, and activities like tai chi may help relax the body and mind.
  • Try to wear loose clothes before going to bed and sleep in a cool, well-ventilated room. Doing this can prevent symptoms of hot flashes and night sweats. Take minimum sleep of 8 hours. 
  • Avoid or limit intake of caffeine-containing beverages, alcohol, and spicy food, as these are known triggering agents for hot flushes.
  • Try to be stress-free to improve your mood swings due to hormonal fluctuations. 
  • Quitting smoking will help reduce hot flashes and your risk of developing chronic conditions like heart disease, stroke, and cancer.

Habit Forming

No

Therapeutic Class

HORMONES

Endochrit Tablet Substitute

Substitutes safety advice
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    12.30per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Endochrit Tablet works by replacing the normal hormone estrogen functions in the body and treats symptoms associated with menopause.

Do not use Endochrit Tablet if you are allergic to peanuts, have unusual vaginal bleeding, have/had any cancer (breast or uterus cancer), or undergoing any other estrogen treatment. Tell your doctor if you had a heart attack, stroke, blood clot, or liver problems, if you are pregnant, breastfeeding, or planning to get pregnant.

No, Endochrit Tablet should not be taken if you are undergoing surgery. You should inform your doctor, and he might ask you to stop hormone replacement therapy about 4 to 6 weeks before surgery to reduce the risk of blood clots.

Endochrit Tablet may cause either weight gain or weight loss. It is a common side effect of Endochrit Tablet . Regular exercise and eating a healthy diet can help prevent weight gain.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PHENYTOIN
  • GRISEOFULVIN
  • RIFAMPICIN
  • RITONAVIR
  • NELFINAVIR
  • EFAVIRENZ
  • BOSENTAN
  • ASPIRIN

Disease/Condition Glossary

Hypoestrogenism: It refers to the lowered secretion of the natural female sex hormone known as estrogen. It is an umbrella term used for estrogen deficiency in various conditions. Its abnormalities may lead to infertility, bone loss, and lipid abnormalities.

Osteoporosis: Osteoporosis means the bone has become porous. It is a disease in which too much bone is lost, and the body makes relatively little bone. As a result, bones become weak and can break easily if you fall.

Hormone replacement therapy (HRT): It is a treatment to relieve symptoms of menopause. It replaces hormones that are at a lower level as you approach menopause.

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