Endoxan Tablet 10's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Hari Kumar , MBBS

MRP ₹42.5

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₹6.4 Cashback (15%)

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Whats That

About Endoxan Tablet

Endoxan Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia, nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Endoxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.

Endoxan Tablet contains ‘Cyclophosphamide’, an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Endoxan Tablet helps to treat cancer by killing the cancer cells.

You are advised to take Endoxan Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.

Do not take Endoxan Tablet if you are allergic to any of its components; or if you have bladder obstruction or other urination problems. Avoid taking Endoxan Tablet if you are pregnant or breastfeeding. Endoxan Tablet may cause dizziness, so drive only if you are alert. Endoxan Tablet should be given to children only if prescribed by the doctor. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Endoxan Tablet

Cancer, nephrotic syndrome (kidney disease)

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Oral liquid: Check the label for directions before use and take the prescribed dose using the dosing syringe or medicine spoon.

Medicinal Benefits

Endoxan Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma(cancer of plasma cells), Burkitt’s lymphoma, leukaemia (blood cancer), neuroblastoma (nerve tissue cancer), retinoblastoma (eye cancer), adenocarcinoma of the ovary (ovarian cancer), mycosis fungoides (T-cell lymphoma), rhabdomyosarcoma (soft tissue cancer), osteosarcoma (bone cancer), and breast carcinoma. Additionally, Endoxan Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in pediatric patients. Endoxan Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Endoxan Tablet helps to treat cancer by killing the cancer cells.

Storage

Keep Endoxan Tablet out of reach and sight of children.

Side effects of Endoxan Asta 50mgtab

Decreased Production Of Blood Cells

Eat well-cooked food to minimize infection risk.
Practice good hand hygiene to prevent infections.
Avoid crowds and people with illnesses to reduce exposure.
Wear a mask when necessary to lower infection risk.
Rest adequately to support your body's healing process.
Stay hydrated by drinking plenty of water.
Regularly monitor blood cell counts for changes.
Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
Consult your doctor right away if concerning symptoms arise.
Follow your doctor's guidance on managing myelosuppression and infection prevention.

Bladder Infection

Bladder infection needs immediate medical attention when you observe blood in urine or have any abnormal changes in your body.
Get a physical examination and blood tests to identify factors that led to infection and initiate the treatment process immediately.
Avoid anxiety and stress, as it can worsen your condition.
Follow your doctor's instructions, and there can be medication with antibiotics and other supportive vitamins.
Take a balanced diet to prevent negative changes in your body.

Small Amounts Of Blood In Urine

Stay hydrated to support kidney and bladder health.
Rest on your back as advised by your doctor.
Limit physical strain for 1-2 weeks.
Avoid strenuous activities like running and contact sports.
Quit smoking to improve overall health.
Use pain medication responsibly.
Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.

Low White Blood Cell Count And Fever

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.

Inflammation Of Mucous Membranes

If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
Practice good hygiene, such as washing your hands regularly, to prevent infection.
Drink plenty of water to keep your mucous membranes hydrated and promote healing.
Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
Follow a soft food diet to reduce discomfort and promote healing.

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Decreased Sperm Production

If you are concerned about impaired spermatogenesis, talk to your doctor. They may adjust the dose if necessary or prescribe alternative medication.
Limit exposure to environmental toxins, smoking, and excessive alcohol consumption.
Regularly monitor hormone levels, such as testosterone and follicle-stimulating hormone (FSH), to detect any changes.
Ensure adequate zinc and folate intake, as these nutrients are essential for spermatogenesis.
Consume omega-3 fatty acid-rich foods or supplements, such as fish oil, to support reproductive health.

Drug Warnings

Do not take Endoxan Tablet if you are allergic to any of its contents; or have urinary flow obstruction, bone marrow suppression, or infections. Talk to your doctor if you have myelosuppression, immunosuppression, infections, diabetes, heart, lung, liver, or kidney problems. Inform your doctor if you are receiving any radiotherapy or chemotherapy. Avoid taking Endoxan Tablet if you are pregnant or breastfeeding. Endoxan Tablet may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Drug-Drug Interactions

CyclophosphamideNalidixic acid

Critical

CyclophosphamideCidofovir

Critical

Drug-Drug Interactions

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CyclophosphamideNalidixic acid

Critical

How does the drug interact with Endoxan Asta 50mgtab:
Co-administration of Nalidixic acid with Endoxan Asta 50mgtab may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Endoxan Asta 50mgtab and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

CyclophosphamideCidofovir

Critical

How does the drug interact with Endoxan Asta 50mgtab:
Co-administration of Endoxan Asta 50mgtab and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor

CyclophosphamideBaricitinib

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Using baricitinib together with Endoxan Asta 50mgtab may increase the risk of serious infections.

How to manage the interaction:
Although there is an interaction, Baricitinib can be taken with Endoxan Asta 50mgtab if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue the medication without consulting a doctor.

CyclophosphamideThalidomide

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Taking Endoxan Asta 50mgtab with Thalidomide may increase the risk of blood clots.

How to manage the interaction:
Although there is a possible interaction, Endoxan Asta 50mgtab can be taken with Thalidomide if prescribed by the doctor. However, consult the doctor if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness, or swelling in an arm or leg. Do not discontinue any medications without a doctor's advice.

CyclophosphamideDeferiprone

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Co-administration of Endoxan Asta 50mgtab and Deferiprone may increase the risk of serious and potential infections.

How to manage the interaction:
Co-administration of Endoxan Asta 50mgtab with Deferiprone can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

CyclophosphamideGolimumab

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Co-administration of Golimumab with Endoxan Asta 50mgtab may increase the risk of serious infections.

How to manage the interaction:
Co-administration of Endoxan Asta 50mgtab with Golimumab can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination. Do not stop using any medications without a doctor's advice.

CyclophosphamideLeflunomide

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Taking Endoxan Asta 50mgtab with Leflunomide may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Endoxan Asta 50mgtab can be taken with Leflunomide if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.

CyclophosphamideAdalimumab

Severe

How does the drug interact with Endoxan Asta 50mgtab:
When Adalimumab is taken with Endoxan Asta 50mgtab, may increase the risk of serious infections.

How to manage the interaction:
Although taking Endoxan Asta 50mgtab and Adalimumab together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

CyclophosphamideTenofovir disoproxil

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Coadministration of Tenofovir disoproxil with Endoxan Asta 50mgtab may increase the risk of developing kidney problems.

How to manage the interaction:
Although there is a possible interaction, Endoxan Asta 50mgtab can be taken with Tenofovir disoproxil if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medication without consulting a doctor.

CyclophosphamideBusulfan

Severe

How does the drug interact with Endoxan Asta 50mgtab:
Co-administration of Endoxan Asta 50mgtab with Busulfan can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Busulfan and Endoxan Asta 50mgtab, they can be taken together if prescribed by a doctor. However, if you experience any vomiting, diarrhea, mouth sores, or stomach pain, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Consume a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
Avoid fast, fried, processed meats, refined carbs, and added sugar.
Get optimal sleep; rest well.
Stay protected from the sun. Avoid tanning beds and cover up with clothing, sunscreen, and sunglasses.

Side Effects of Endoxan Tablet

Fever
Nausea
Vomiting
Diarrhoea
Hair loss
Low blood cell count
Abdominal pain

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:39 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

CYCLOPHOSPHAMIDE-50MgOther diseases of blood and blood-forming organs

Severe

CYCLOPHOSPHAMIDE-50MgObstructive and reflux uropathy

Severe

Drug-Diseases Interactions

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CYCLOPHOSPHAMIDE-50MgOther diseases of blood and blood-forming organs

Severe

How does the disease interact with Endoxan Asta 50mgtab:
Endoxan Asta 50mgtab usage can result in severe immunosuppression, bone marrow failure, myelosuppression (leukopenia, neutropenia, thrombocytopenia, and anaemia), and myelosuppression, which can all lead to serious and occasionally deadly infections including sepsis and septic shock. During Endoxan Asta 50mgtab treatment, complete blood counts must be closely monitored in order to determine whether the dose has to be changed. Patients should not be given Endoxan Asta 50mgtab if their neutrophil and platelet counts are below 1,500/mm3 and 50,000/mm3, respectively.

How to manage the interaction:
Close monitoring of complete blood count is advised during treatment with Endoxan Asta 50mgtab. Inform the doctor if you notice any signs or symptoms of bone marrow suppression such as fever, sore throat, local infection, or bleeding.

CYCLOPHOSPHAMIDE-50MgObstructive and reflux uropathy

Severe

How does the disease interact with Endoxan Asta 50mgtab:
Endoxan Asta 50mgtab should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Endoxan Asta 50mgtab treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Endoxan Asta 50mgtab should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.

CYCLOPHOSPHAMIDE-50MgObstructive and reflux uropathy

Severe

How does the disease interact with Endoxan Asta 50mgtab:
Endoxan Asta 50mgtab should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Endoxan Asta 50mgtab treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Endoxan Asta 50mgtab should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.

CYCLOPHOSPHAMIDE-50MgObstructive and reflux uropathy

Severe

How does the disease interact with Endoxan Asta 50mgtab:
Endoxan Asta 50mgtab should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Endoxan Asta 50mgtab treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Endoxan Asta 50mgtab should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.

FAQs

How does Endoxan Tablet work?

Endoxan Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Endoxan Tablet helps to treat cancer by killing the cancer cells.

Can I stop taking Endoxan Tablet on my own?

Do not stop taking Endoxan Tablet on your own. You are advised to take Endoxan Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Endoxan Tablet .

Does Endoxan Tablet cause infertility?

Endoxan Tablet might interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm) and could impair fertility. Before starting treatment with Endoxan Tablet , talk to your doctor regarding cryopreservation/freezing of eggs/sperm if you consider becoming parents.

Does Endoxan Tablet interfere with wound healing?

Endoxan Tablet might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding, or bruising or if the wounds do not heal properly.

Is it safe to father a child while taking Endoxan Tablet ?

No, it is not safe to father a child while taking Endoxan Tablet . Use effective contraception while taking Endoxan Tablet and for at least four months after treatment. Women of childbearing age taking Endoxan Tablet should use highly effective contraceptives while taking Endoxan Tablet up to 1 year after the treatment.

Does Endoxan Tablet affect blood cell count?

Endoxan Tablet might cause myelosuppression/bone marrow suppression leading to a decrease in white blood cells. This could lead to an increased risk of infections. Regular blood tests while taking Endoxan Tablet are advised.

Drug-Drug Interactions Checker List

DOXORUBICIN
PACLITAXEL
APREPITANT
ONDANSETRON
ZIDOVUDINE

Special Advise

Monitoring of complete blood count while taking Endoxan Tablet is advised.
Drink plenty of fluids to prevent urinary problems.
If you are due to have any surgery, inform the doctor that you are taking Endoxan Tablet .

Disease/Condition Glossary

Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner, leading to tumour formation. Tumours could be benign/non-cancerous or malignant/cancerous. Lymphoma is a cancer of the lymphatic system, which is the body’s disease-fighting system. It includes lymph nodes, spleen, bone marrow, and thymus. Symptoms include enlarged lymph nodes, weight loss, and fatigue. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy, and targeted drug therapy.

Nephrotic syndrome: It is a kidney disorder with symptoms such as protein in the urine, high cholesterol levels, low blood protein levels, high triglyceride levels, and swelling.