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  3. Phoscan 50mg Tablet

Phoscan 50mg Tablet, Pack of 1 Tablet
Phoscan 50mg Tablet, Pack of 1 Tablet
Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
Know More
COD available

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Whats That

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Composition :

CYCLOPHOSPHAMIDE-50MG

Manufacturer/Marketer :

Enrico Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Phoscan 50mg Tablet

Phoscan 50mg Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as lymphoma (Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma, Burkitt’s lymphoma, mycosis fungoide), leukaemia,  nerve tissue cancer, eye cancer, ovarian cancer, soft tissue cancer, bone cancer, and breast cancer. Additionally, Phoscan 50mg Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in paediatric patients.
 
Phoscan 50mg Tablet contains ‘Cyclophosphamide’, an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Phoscan 50mg Tablet helps to treat cancer by killing the cancer cells.
 
You are advised to take Phoscan 50mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as fever, nausea, vomiting, diarrhoea, hair loss, low blood cell count, and abdominal pain. Do not be reluctant to talk with your doctor if you experience any of these side effects persistently.
 
Do not take Phoscan 50mg Tablet if you are allergic to any of its components; or if you have bladder obstruction or other urination problems. Avoid taking Phoscan 50mg Tablet if you are pregnant or breastfeeding. Phoscan 50mg Tablet may cause dizziness, so drive only if you are alert. Phoscan 50mg Tablet should be given to children only if prescribed by the doctor. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Phoscan 50mg Tablet

Cancer, nephrotic syndrome (kidney disease)

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not crush or chew it.Oral liquid: Check the label for directions before use and take the prescribed dose using the dosing syringe or medicine spoon.

Medicinal Benefits

Phoscan 50mg Tablet belongs to the group of anti-cancer medicines used to treat malignant diseases such as Hodgkin’s disease, mixed-cell type lymphoma, lymphocytic lymphoma, histiocytic lymphoma, multiple myeloma(cancer of plasma cells), Burkitt’s lymphoma, leukaemia (blood cancer), neuroblastoma (nerve tissue cancer), retinoblastoma (eye cancer), adenocarcinoma of the ovary (ovarian cancer), mycosis fungoides (T-cell lymphoma), rhabdomyosarcoma (soft tissue cancer), osteosarcoma (bone cancer), and breast carcinoma. Additionally, Phoscan 50mg Tablet is used to treat minimal change nephrotic syndrome (kidney disease) in pediatric patients. Phoscan 50mg Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Phoscan 50mg Tablet helps to treat cancer by killing the cancer cells.

Storage

Store in a cool and dry place away from sunlight
Side effects of Phoscan 50mg Tablet
  • Eat well-cooked food to minimize infection risk.
  • Practice good hand hygiene to prevent infections.
  • Avoid crowds and people with illnesses to reduce exposure.
  • Wear a mask when necessary to lower infection risk.
  • Rest adequately to support your body's healing process.
  • Stay hydrated by drinking plenty of water.
  • Regularly monitor blood cell counts for changes.
  • Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
  • Consult your doctor right away if concerning symptoms arise.
  • Follow your doctor's guidance on managing myelosuppression and infection prevention.
  • Bladder infection needs immediate medical attention when you observe blood in urine or have any abnormal changes in your body.
  • Get a physical examination and blood tests to identify factors that led to infection and initiate the treatment process immediately.
  • Avoid anxiety and stress, as it can worsen your condition.
  • Follow your doctor's instructions, and there can be medication with antibiotics and other supportive vitamins.
  • Take a balanced diet to prevent negative changes in your body.
  • Stay hydrated to support kidney and bladder health.
  • Rest on your back as advised by your doctor.
  • Limit physical strain for 1-2 weeks.
  • Avoid strenuous activities like running and contact sports.
  • Quit smoking to improve overall health.
  • Use pain medication responsibly.
  • Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
  • Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
  • Practice good hygiene, such as washing your hands regularly, to prevent infection.
  • Drink plenty of water to keep your mucous membranes hydrated and promote healing.
  • Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
  • Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
  • Follow a soft food diet to reduce discomfort and promote healing.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • If you are concerned about impaired spermatogenesis, talk to your doctor. They may adjust the dose if necessary or prescribe alternative medication.
  • Limit exposure to environmental toxins, smoking, and excessive alcohol consumption.
  • Regularly monitor hormone levels, such as testosterone and follicle-stimulating hormone (FSH), to detect any changes.
  • Ensure adequate zinc and folate intake, as these nutrients are essential for spermatogenesis.
  • Consume omega-3 fatty acid-rich foods or supplements, such as fish oil, to support reproductive health.

Drug Warnings

Do not take Phoscan 50mg Tablet if you are allergic to any of its contents; or have urinary flow obstruction, bone marrow suppression, or infections. Talk to your doctor if you have myelosuppression, immunosuppression, infections, diabetes, heart, lung, liver, or kidney problems. Inform your doctor if you are receiving any radiotherapy or chemotherapy. Avoid taking Phoscan 50mg Tablet if you are pregnant or breastfeeding. Phoscan 50mg Tablet may cause dizziness, so drive only if you are alert. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Drug-Drug Interactions

verifiedApollotooltip
CyclophosphamideCidofovir
Critical
CyclophosphamideNalidixic acid
Critical

Drug-Drug Interactions

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CyclophosphamideCidofovir
Critical
How does the drug interact with Phoscan 50mg Tablet:
Co-administration of Phoscan 50mg Tablet and Cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Taking Cyclophosphamine with Cidofovir is not recommended, please consult your doctor before taking it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not discontinue any medications without consulting a doctor
CyclophosphamideNalidixic acid
Critical
How does the drug interact with Phoscan 50mg Tablet:
Co-administration of Nalidixic acid with Phoscan 50mg Tablet may cause an increase in the risk of side effects.

How to manage the interaction:
Co-administration of Phoscan 50mg Tablet and Nalidixic acid can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like bruising or bleeding, unusual weakness, nausea, stomach pain, low fever, or loss of appetite, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
CyclophosphamideLidocaine
Severe
How does the drug interact with Phoscan 50mg Tablet:
Taking Lidocaine with Phoscan 50mg Tablet may increase the risk of methemoglobinemia (a rare condition that can lead to oxygen deprivation in tissues and vital organs due to reduced oxygen-carrying capacity of the blood).

How to manage the interaction:
Although there is a possible interaction, Phoscan 50mg Tablet can be taken with lidocaine if prescribed by the doctor. However, consult the doctor if you experience gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, weakness, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not discontinue the medication without consulting a doctor.
CyclophosphamideBusulfan
Severe
How does the drug interact with Phoscan 50mg Tablet:
Co-administration of Phoscan 50mg Tablet with Busulfan can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Busulfan and Phoscan 50mg Tablet, they can be taken together if prescribed by a doctor. However, if you experience any vomiting, diarrhea, mouth sores, or stomach pain, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
CyclophosphamideRopivacaine
Severe
How does the drug interact with Phoscan 50mg Tablet:
Co-administration of Ropivacaine with Phoscan 50mg Tablet can cause methemoglobinemia (low levels of oxygen in the blood).

How to manage the interaction:
Although there is a possible interaction between Ropivacaine and Phoscan 50mg Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
CyclophosphamideLevobupivacaine
Severe
How does the drug interact with Phoscan 50mg Tablet:
Co-administration of Phoscan 50mg Tablet with Levobupivacaine can increase the risk of methemoglobinemia (low level of oxygen in the blood).

How to manage the interaction:
Co-administration of Levobupivacaine with Phoscan 50mg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. Keep a close eye on any signs or symptoms of Methemoglobinemia. If you notice any of these symptoms like gray skin, feeling sick, headaches, dizziness, tiredness, or trouble breathing, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
CyclophosphamideThalidomide
Severe
How does the drug interact with Phoscan 50mg Tablet:
Taking Phoscan 50mg Tablet with Thalidomide may increase the risk of blood clots.

How to manage the interaction:
Although there is a possible interaction, Phoscan 50mg Tablet can be taken with Thalidomide if prescribed by the doctor. However, consult the doctor if you experience chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness, or swelling in an arm or leg. Do not discontinue any medications without a doctor's advice.
CyclophosphamideVoclosporin
Severe
How does the drug interact with Phoscan 50mg Tablet:
Co-administration of Phoscan 50mg Tablet with Voclosporin can increase the risk of kidney damage.

How to manage the interaction:
Although there is a possible interaction between Phoscan 50mg Tablet and Voclosporin, you can take these medicines together if prescribed by a doctor. It's important to keep an eye on how much you pee. Some other signs to watch out for are feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, holding onto fluids, having a fever or chills, having diarrhea or a sore throat, feeling weak or dizzy, being confused, having trouble breathing, feeling pain or a burning sensation when you pee, or having an irregular heartbeat. Do not stop using any medications without talking to a doctor.
CyclophosphamideTofacitinib
Severe
How does the drug interact with Phoscan 50mg Tablet:
Taking Phoscan 50mg Tablet with Tofacitinib may increase the risk of serious infections.

How to manage the interaction:
Although there is a possible interaction, Phoscan 50mg Tablet can be taken with Tofacitinib if prescribed by the doctor. Consult the doctor immediately if you develop signs and symptoms of infection such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue the medication without consulting a doctor.
CyclophosphamideCladribine
Severe
How does the drug interact with Phoscan 50mg Tablet:
The combined use of Cladribine with Phoscan 50mg Tablet can increase the risk and severity of side effects.

How to manage the interaction:
Co-administration of Cladribine with Phoscan 50mg Tablet can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, contact a doctor right away. These symptoms include complications, infection, fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep; rest well.
  • Stay protected from the sun. Avoid tanning beds and cover up with clothing, sunscreen, and sunglasses.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Phoscan 50mg Tablet Substitute

Substitutes safety advice

  • Cycloxan Tablet 10's

    by Others

    ₹3.66per tablet

  • Adcyclo 50 Tablet 10's

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    ₹3.51per tablet

  • Endoxan Tablet 10's

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    ₹3.83per tablet

  • Endoxan Tablet 10's

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    ₹3.83per tablet

  • Eldamide 50mg Tablet

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    ₹2.03per tablet

Product Substitutes

Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Hari Kumar

Reviewed By

Hari Kumar

MBBS

Last Updated

Aug 20, 2024 | 1:08 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
CYCLOPHOSPHAMIDE-50MGOther diseases of blood and blood-forming organs
Severe
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe

Drug-Diseases Interactions

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CYCLOPHOSPHAMIDE-50MGOther diseases of blood and blood-forming organs
Severe
How does the disease interact with Phoscan 50mg Tablet:
Phoscan 50mg Tablet usage can result in severe immunosuppression, bone marrow failure, myelosuppression (leukopenia, neutropenia, thrombocytopenia, and anaemia), and myelosuppression, which can all lead to serious and occasionally deadly infections including sepsis and septic shock. During Phoscan 50mg Tablet treatment, complete blood counts must be closely monitored in order to determine whether the dose has to be changed. Patients should not be given Phoscan 50mg Tablet if their neutrophil and platelet counts are below 1,500/mm3 and 50,000/mm3, respectively.

How to manage the interaction:
Close monitoring of complete blood count is advised during treatment with Phoscan 50mg Tablet. Inform the doctor if you notice any signs or symptoms of bone marrow suppression such as fever, sore throat, local infection, or bleeding.
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe
How does the disease interact with Phoscan 50mg Tablet:
Phoscan 50mg Tablet should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Phoscan 50mg Tablet treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Phoscan 50mg Tablet should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe
How does the disease interact with Phoscan 50mg Tablet:
Phoscan 50mg Tablet should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Phoscan 50mg Tablet treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Phoscan 50mg Tablet should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.
CYCLOPHOSPHAMIDE-50MGObstructive and reflux uropathy
Severe
How does the disease interact with Phoscan 50mg Tablet:
Phoscan 50mg Tablet should not be administered to individuals who have any type of urine outflow restriction. Urinary blockage should be ruled out or resolved before therapy is started. During Phoscan 50mg Tablet treatment, hemorrhagic cystitis, pyelitis, and hematuria have all been mentioned.

How to manage the interaction:
Therapy with Phoscan 50mg Tablet should be administered cautiously in patients with or predisposed to bladder inflammation, including patients with active urinary infections. Urinary sediment should be monitored regularly for presence or erythrocytes and other signs of toxicity.

FAQs

Phoscan 50mg Tablet is an alkylating agent that stops the growth and multiplication of cancer cells by damaging their genetic material. Thereby, Phoscan 50mg Tablet helps to treat cancer by killing the cancer cells.

Do not stop taking Phoscan 50mg Tablet on your own. You are advised to take Phoscan 50mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Phoscan 50mg Tablet.

Phoscan 50mg Tablet might interfere with oogenesis (development of ovum) and spermatogenesis (development of sperm) and could impair fertility. Before starting treatment with Phoscan 50mg Tablet, talk to your doctor regarding cryopreservation/freezing of eggs/sperm if you consider becoming parents.

Phoscan 50mg Tablet might interfere with normal wound healing. Therefore, be cautious while handling sharp objects. Consult your doctor if you notice unusual bleeding, or bruising or if the wounds do not heal properly.

No, it is not safe to father a child while taking Phoscan 50mg Tablet. Use effective contraception while taking Phoscan 50mg Tablet and for at least four months after treatment. Women of childbearing age taking Phoscan 50mg Tablet should use highly effective contraceptives while taking Phoscan 50mg Tablet up to 1 year after the treatment.

Phoscan 50mg Tablet might cause myelosuppression/bone marrow suppression leading to a decrease in white blood cells. This could lead to an increased risk of infections. Regular blood tests while taking Phoscan 50mg Tablet are advised.

Drug-Drug Interactions Checker List

  • DOXORUBICIN
  • PACLITAXEL
  • APREPITANT
  • ONDANSETRON
  • ZIDOVUDINE

Special Advise

  • Monitoring of complete blood count while taking Phoscan 50mg Tablet is advised.
  • Drink plenty of fluids to prevent urinary problems.
  • If you are due to have any surgery, inform the doctor that you are taking Phoscan 50mg Tablet.

Disease/Condition Glossary

Cancer: It occurs due to mutations in genes that regulate cell growth. The mutations cause the cells to divide and multiply in an uncontrolled manner, leading to tumour formation. Tumours could be benign/non-cancerous or malignant/cancerous. Lymphoma is a cancer of the lymphatic system, which is the body’s disease-fighting system. It includes lymph nodes, spleen, bone marrow, and thymus. Symptoms include enlarged lymph nodes, weight loss, and fatigue. The most common cancer treatment methods are surgery, chemotherapy, radiotherapy, bone marrow (stem cell) transplantation, immunotherapy, and targeted drug therapy.

Nephrotic syndrome: It is a kidney disorder with symptoms such as protein in the urine, high cholesterol levels, low blood protein levels, high triglyceride levels, and swelling.

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