apollo
0
Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS

About Entacom Plus 150 Tablet 10's

Entacom Plus 150 Tablet 10's belongs to a class of drugs called 'antiparkinson agents', a precursor of dopamine (chemical messenger in the brain) primarily used in treating Parkinson's disease with its symptoms including tremors, spasms, muscle stiffness and poor muscle control. Parkinson's disease is a disorder of the central nervous system that affects movement and locomotion, which causes stiffness, shaking, and difficulty in walking, coordination and balance. In Parkinson's patients, there are low dopamine levels as the nerve cells of the brain (neurons) that produce dopamine begin to die.

Entacom Plus 150 Tablet 10's contains Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the central nervous system agents, while Carbidopa is a decarboxylase inhibitor. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. Carbidopa prevents the breakdown of Levodopa in the bloodstream so that more Levodopa can reach the brain. On the other hand, Entacapone belongs to a class of COMT (catechol-o-methyltransferase enzyme) inhibitors which causes higher and more sustained levels of Levodopa in the blood that more Levodopa can reach the brain, leading to greater relief from the symptoms of Parkinson's disease.

Take Entacom Plus 150 Tablet 10's as prescribed by your doctor. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. The most common side effects of Entacom Plus 150 Tablet 10's are nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Most of these side effects of Entacom Plus 150 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Entacom Plus 150 Tablet 10's or any other medicines, please tell your doctor. Do not take Entacom Plus 150 Tablet 10's if you are pregnant or breastfeeding unless prescribed by the doctor. Entacom Plus 150 Tablet 10's should not be given to children as safety and effectiveness have not been established. Entacom Plus 150 Tablet 10's may cause hallucinations (seeing or hearing things that are not there) in some cases if taken for a prolonged time. So, if you experience hallucinations while taking Entacom Plus 150 Tablet 10's, please talk to your doctor immediately. Keep your doctor informed about your medicines and health condition and rule out any side effects.

rxMedicinePrescription drug

Whats That

tooltip
Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Intas Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Entacom Plus 150 Tablet 10's

Parkinson’s disease

Medicinal Benefits

Entacom Plus 150 Tablet 10's is an antiparkinson agent that is used in the treatment of Parkinson’s disease. Entacom Plus 150 Tablet 10's is a combination of three medicines: Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the class of medications name as central nervous system agents, While Carbidopa falls in decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. At the same time, Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can effectively reach the brain to block acetylcholine (a chemical messenger in the brain). Entacapone blocks a certain natural substance, catechol-o-methyltransferase (COMT) (an enzyme that breaks down the levodopa in the body), which causes higher and more sustained levels of levodopa in the blood, so that more Levodopa can reach the brain, leading to greater relief from the symptoms of Parkinson’s disease. This effect allows the levodopa to last longer in the body so that it doesn't wear off before the next dose.

Side Effects of Entacom Plus 150 Tablet 10's

  • Nausea
  • Muscle pain
  • Diarrhoea
  • Lightheadedness
  • Dizziness
  • Stomach upset
  • Blurred vision
  • Anaemia
  • Hypotension (low blood pressure)
  • Dyskinesias (uncontrolled movement)
  • Urine discolouration

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not stop taking Entacom Plus 150 Tablet 10's suddenly without talking to your doctor. It may result in a serious neuroleptic malignant syndrome (NMS) that causes fever, muscle cramps or stiffness, unusual body movements, fast heartbeat, sweating, change in thinking, and confusion. Do not take Entacom Plus 150 Tablet 10's if you are allergic to Entacom Plus 150 Tablet 10's or any of its ingredients. Tell your doctor if you have any medical history of diabetes, heart attacks, mental illness, stomach ulcers, heart disease, or have recently undergone a surgical procedure. Entacom Plus 150 Tablet 10's may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking Entacom Plus 150 Tablet 10's so please get up gradually. Besides this, a prolonged intake of Entacom Plus 150 Tablet 10's may lead to greater neuropathy chances (nerve damage). Entacom Plus 150 Tablet 10's should be given with caution in patients with eye problems (narrow-angle glaucoma), irregular heartbeat (arrhythmia), gastrointestinal bleeding, and psychosis. The use of Entacom Plus 150 Tablet 10's is restricted if a person takes monoamine oxidase inhibitors (MAOs) or antidepressant drugs like isocarboxazid, phenelzine, selegiline, and tranylcypromine because it can lead to high blood pressure (hypertension) crisis.

Therapeutic Class

ANTIPARKINSON AGENTS

Drug-Drug Interactions

verifiedApollotooltip
EntacaponeLinezolid
Critical
EntacaponePhenelzine
Critical

Drug-Drug Interactions

Login/Sign Up

EntacaponeLinezolid
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Coadministration of Entacom Plus 150 Tablet 10's with Linezolid might raise serotonin hormone levels in the body, affecting the brain and nerve cells.

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Linezolid is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EntacaponePhenelzine
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Combining Entacom Plus 150 Tablet 10's with Phenelzine can increase the risk of serious condition called the serotonin syndrome.

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Phenelzine is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
EntacaponeIsocarboxazid
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Combining Entacom Plus 150 Tablet 10's with Isocarboxazid can increase the risk of serious condition called the serotonin syndrome.

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Isocarboxazid is not recommended as it can result in an interaction; it can be taken if your doctor has advised it. However, if you experience sudden extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea, Contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EntacaponeTranylcypromine
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Coadministration of Entacom Plus 150 Tablet 10's with Tranylcypromine can increase the risk of high blood pressure and also increase the risk of serotonin syndrome(a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Tranylcypromine can result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
LevodopaProcarbazine
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Using Entacom Plus 150 Tablet 10's together with procarbazine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Procarbazine with Entacom Plus 150 Tablet 10's together can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaTranylcypromine
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Taking Tranylcypromine with Entacom Plus 150 Tablet 10's can increase the risk of high blood pressure

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Tranylcypromine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
LevodopaPhenelzine
Critical
How does the drug interact with Entacom Plus 150 Tablet 10's:
Using Entacom Plus 150 Tablet 10's together with phenelzine can increase blood pressure and increase the risk of side effects.

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Phenelzine is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness and fainting. Do not discontinue any medications without consulting your doctor.
EntacaponeMethylene blue
Severe
How does the drug interact with Entacom Plus 150 Tablet 10's:
Combining Entacom Plus 150 Tablet 10's with Methylene blue can increase the risk of CNS depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Entacom Plus 150 Tablet 10's with Methylene blue together can result in an interaction, but it can be taken if your doctor has advised it. It's important to keep an eye on your health. If you notice any of these signs - very high blood pressure, feeling confused or hallucinating, having a seizure, a fast heartbeat, fever, sweating a lot, shivering or shaking, trouble seeing clearly, muscle spasms or stiffness, difficulty coordinating movements, stomach cramps, feeling sick, throwing up, or having diarrhea - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
EntacaponeEsketamine
Severe
How does the drug interact with Entacom Plus 150 Tablet 10's:
Combining Entacom Plus 150 Tablet 10's with Esketamine can increase the risk and severity of side effects (drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination).

How to manage the interaction:
Although taking Entacom Plus 150 Tablet 10's and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. If you're having any of these symptoms like feeling sleepy, having trouble concentrating, or feeling confused, it's important to let a doctor know right away. Do not stop using any medications without talking to a doctor.
EntacaponeProcarbazine
Severe
How does the drug interact with Entacom Plus 150 Tablet 10's:
Combining Entacom Plus 150 Tablet 10's with Procarbazine can increase the risk or severity of side effects like decreased rate of breathing, decreased heart rate, and loss of consciousness.

How to manage the interaction:
Although taking Entacom Plus 150 Tablet 10's and Procarbazine together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any symptoms like confusion, hallucinations, seizures, fast heartbeat, fever, sweating, shivering, blurred vision, muscle spasms, stiffness, trouble moving, cramps, feeling sick, throwing up, or having diarrhea - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

Login/Sign Up

Drug-Drug Interactions Checker List

  • RASAGILINE
  • SELEGILINE
  • PRAMIPEXOLE
  • APOMORPHINE
  • MOCLOBEMIDE
  • AMITRIPTYLINE
  • DESIPRAMINE
  • MAPROTILINE
  • VENLAFAXINE
  • PAROXETINE
  • ISOPRENALINE
  • ADRENALINE
  • METHYLDOPA
  • FUROSEMIDE
  • ATORVASTATIN
  • PYRIDOXINE (VITB6)
  • PHENYTOIN
  • METOCLOPRAMIDE
  • PHENOTHIAZINE
  • RISPERIDONE
  • ERYTHROMYCIN
  • RIFAMPICIN
  • AMPICILLIN
  • CHLORAMPHENICOL
  • ISONIAZID
  • NORADRENALINE
  • RIMITEROLE
  • PAPAVERINE
  • BUTYROPHENONES

Diet & Lifestyle Advise

  • Drink plenty of water to avoid headaches due to dehydration. 
  • Limit the consumption of sugar-containing food or food with too many calories but fewer nutrients, as it may cause tooth decay.
  • Engaging in physical activity like dancing or exercising will boost the metabolism and make a person more energetic.
  • Avoid intake of alcoholic beverages with Entacom Plus 150 Tablet 10's as it can make a person dehydrated and may affect their sleep. This can make it harder for a person’s body to aid the Entacom Plus 150 Tablet 10's in fighting off infections.

Habit Forming

No

Special Advise

  • Do not exceed more than 1 dose (2 capsules) for any off period (recurring symptoms in between regular doses).
  • If you have unusual urges like gambling, spending money, overeating, or increased sexual urges, please inform your doctor before taking the Entacom Plus 150 Tablet 10's.

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Disease/Condition Glossary

Parkinson’s disease: It is a disorder of central nervous system that affects movement due to damage of nerve cells in the brain which reduces the levels of dopamine and leads to symptoms such as stiffness, tremor in one hand, shaking, difficulty in walking, coordination and balance. This condition can last for many years or life-long. Treatment with medicines along with physiotherapy may help to control the symptoms and provide a quality life for as long as possible.

Entacom Plus 150 Tablet 10's Substitute

Substitutes safety advice
  • SYNCAP ONE 150MG TABLET

    13.32per tablet
whatsapp Floating Button

Recommended for a 30-day course: 9 Strips

Add 9 Strips