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About SYNCAP ONE 150MG TABLET
SYNCAP ONE 150MG TABLET belongs to a class of drugs called 'antiparkinson agents', a precursor of dopamine (chemical messenger in the brain) primarily used in treating Parkinson's disease with its symptoms including tremors, spasms, muscle stiffness and poor muscle control. Parkinson's disease is a disorder of the central nervous system that affects movement and locomotion, which causes stiffness, shaking, and difficulty in walking, coordination and balance. In Parkinson's patients, there are low dopamine levels as the nerve cells of the brain (neurons) that produce dopamine begin to die.
SYNCAP ONE 150MG TABLET contains Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the central nervous system agents, while Carbidopa is a decarboxylase inhibitor. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. Carbidopa prevents the breakdown of Levodopa in the bloodstream so that more Levodopa can reach the brain. On the other hand, Entacapone belongs to a class of COMT (catechol-o-methyltransferase enzyme) inhibitors which causes higher and more sustained levels of Levodopa in the blood that more Levodopa can reach the brain, leading to greater relief from the symptoms of Parkinson's disease.
Take SYNCAP ONE 150MG TABLET as prescribed by your doctor. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. The most common side effects of SYNCAP ONE 150MG TABLET are nausea, vomiting, loss of appetite, light-headedness, lowered blood pressure, confusion, and dyskinesia (uncontrolled/involuntary muscle movement). Most of these side effects of SYNCAP ONE 150MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are known to be allergic to SYNCAP ONE 150MG TABLET or any other medicines, please tell your doctor. Do not take SYNCAP ONE 150MG TABLET if you are pregnant or breastfeeding unless prescribed by the doctor. SYNCAP ONE 150MG TABLET should not be given to children as safety and effectiveness have not been established. SYNCAP ONE 150MG TABLET may cause hallucinations (seeing or hearing things that are not there) in some cases if taken for a prolonged time. So, if you experience hallucinations while taking SYNCAP ONE 150MG TABLET, please talk to your doctor immediately. Keep your doctor informed about your medicines and health condition and rule out any side effects.
Uses of SYNCAP ONE 150MG TABLET
Directions for Use
Medicinal Benefits
SYNCAP ONE 150MG TABLET is an antiparkinson agent that is used in the treatment of Parkinson’s disease. SYNCAP ONE 150MG TABLET is a combination of three medicines: Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the class of medications name as central nervous system agents, While Carbidopa falls in decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. At the same time, Carbidopa acts by preventing the breakdown of Levodopa in the bloodstream so that more Levodopa can effectively reach the brain to block acetylcholine (a chemical messenger in the brain). Entacapone blocks a certain natural substance, catechol-o-methyltransferase (COMT) (an enzyme that breaks down the levodopa in the body), which causes higher and more sustained levels of levodopa in the blood, so that more Levodopa can reach the brain, leading to greater relief from the symptoms of Parkinson’s disease. This effect allows the levodopa to last longer in the body so that it doesn't wear off before the next dose.
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Side Effects of SYNCAP ONE 150MG TABLET
Drug Warnings
Do not stop taking SYNCAP ONE 150MG TABLET suddenly without talking to your doctor. It may result in a serious neuroleptic malignant syndrome (NMS) that causes fever, muscle cramps or stiffness, unusual body movements, fast heartbeat, sweating, change in thinking, and confusion. Do not take SYNCAP ONE 150MG TABLET if you are allergic to SYNCAP ONE 150MG TABLET or any of its ingredients. Tell your doctor if you have any medical history of diabetes, heart attacks, mental illness, stomach ulcers, heart disease, or have recently undergone a surgical procedure. SYNCAP ONE 150MG TABLET may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, especially when you start taking SYNCAP ONE 150MG TABLET so please get up gradually. Besides this, a prolonged intake of SYNCAP ONE 150MG TABLET may lead to greater neuropathy chances (nerve damage). SYNCAP ONE 150MG TABLET should be given with caution in patients with eye problems (narrow-angle glaucoma), irregular heartbeat (arrhythmia), gastrointestinal bleeding, and psychosis. The use of SYNCAP ONE 150MG TABLET is restricted if a person takes monoamine oxidase inhibitors (MAOs) or antidepressant drugs like isocarboxazid, phenelzine, selegiline, and tranylcypromine because it can lead to high blood pressure (hypertension) crisis.
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SYNCAP ONE 150MG TABLET is a combination of three medicines namely; Carbidopa, Levodopa, and Entacapone. Levodopa belongs to the class of medications name as central nervous system agents, While Carbidopa fall in the category of decarboxylase inhibitors. The medicinal component Levodopa changes into dopamine in the brain and helps to control movement. While Carbidopa and Entacapone act by preventing the breakdown and causes higher and more sustained levels of Levodopa in the bloodstream so that more Levodopa can reach to brain.
Take SYNCAP ONE 150MG TABLET medicine precisely as the doctor has directed. Take one dose on a regular basis. Try to take the tablets at the same time of day every day, as this will assist you in making sure to take them.
In some cases, prolonged intake of SYNCAP ONE 150MG TABLET may lead to autoimmune hemolytic anaemia (red blood cells in the blood are destroyed earlier than normal). Levodopa in SYNCAP ONE 150MG TABLET can cause the immune system to mistake your own red blood cells for foreign substances. The body responds by making antibodies to attack the body's own red blood cells. The antibodies attach to red blood cells and cause them to break down too early. So, your doctor might recommend regular blood tests while using SYNCAP ONE 150MG TABLET.
You are recommended to avoid taking protein-rich food (such as chicken, beef, pork, eggs, meats, fish, dairy products, seeds, and nuts), iron supplements, or multivitamin tablets while taking SYNCAP ONE 150MG TABLET as it may delay and reduce the absorption of levodopa. Thus, reduce the effectiveness of SYNCAP ONE 150MG TABLET. Please consult your doctor and do as advised for the best results.
Yes, orthostatic hypotension could be a side-effect of SYNCAP ONE 150MG TABLET. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking SYNCAP ONE 150MG TABLET are advised to regularly monitor their blood pressure levels to avoid unpleasant events.
Consult your doctor before taking SYNCAP ONE 150MG TABLET if you have glaucoma. SYNCAP ONE 150MG TABLET is contraindicated in patients with narrow-angle glaucoma. SYNCAP ONE 150MG TABLET may cause blindness on long-term use in the case of patients with narrow-angle glaucoma.
Hallucination is a medical condition in which the person may feel, hear, or believe things that are not true, see things that are not there, or feel unusually suspicious or confused. SYNCAP ONE 150MG TABLET may cause hallucinations in some cases if taken for a prolonged time. So, if you experience hallucinations while taking SYNCAP ONE 150MG TABLET, please talk to your doctor immediately.
It is advised not to stop taking SYNCAP ONE 150MG TABLET without consulting your doctor as it may lead to a severe condition called withdrawal-emergent hyperpyrexia with symptoms such as confusion, fever, muscle stiffness, changes in heartbeat, and breathing. Therefore, take SYNCAP ONE 150MG TABLET for as long as your doctor has prescribed it and if you experience any of these symptoms while taking SYNCAP ONE 150MG TABLET, please consult your doctor so that the dose may be gradually reduced.
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Special Advise
Disease/Condition Glossary
Parkinson’s disease: It is a disorder of central nervous system that affects movement due to damage of nerve cells in the brain which reduces the levels of dopamine and leads to symptoms such as stiffness, tremor in one hand, shaking, difficulty in walking, coordination and balance. This condition can last for many years or life-long. Treatment with medicines along with physiotherapy may help to control the symptoms and provide a quality life for as long as possible.
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