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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Enzoflam-SP Tablet

Enzoflam-SP Tablet belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Enzoflam-SP Tablet is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal. 

You can take Enzoflam-SP Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.  Most of the side effects of Enzoflam-SP Tablet do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain etc. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Enzoflam-SP Tablet if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Enzoflam-SP Tablet

 Pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Enzoflam-SP Tablet consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Paracetamol acts as mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue. Together these not only reduce pain and inflammation but also help in faster healing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enzoflam-SP Tablet

  • Nausea

  • Stomach Pain

  • Loss of appetite

  • Diarrhoea

  • Stomach upset

  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Enzoflam-SP Tablet as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Enzoflam-SP Tablet on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Enzoflam-SP Tablet . Use with caution in pregnancy and breastfeeding. Do not self-administer Enzoflam-SP Tablet if you are pregnant or are nursing.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacSulindac
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Enzoflam-SP Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacSulindac
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet and sulindac can increase the risk of side effects.

How to manage the interaction:
Although there is a interaction between Enzoflam-SP Tablet and sulindac, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacCidofovir
Severe
How does the drug interact with Enzoflam-SP Tablet:
Coadministration of Enzoflam-SP Tablet with cidofovir may increase the risk of kidney problems.

How to manage the interaction:
Although taking Enzoflam-SP Tablet and cidofovir together can possibly cause an interaction, it can be taken if your doctor has suggested it. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacVorapaxar
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacAmiloride
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking amiloride with Enzoflam-SP Tablet can increase the risk of kidney problems, hyperkalemia(high potassium levels in blood), and high blood pressure.

How to manage the interaction:
There could be a possible interaction between Enzoflam-SP Tablet and amiloride, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacKetorolac
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet and Ketorolac can increase the risk of side effects.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Ketorolac can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacValdecoxib
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Valdecoxib with Enzoflam-SP Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacMethotrexate
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of methotrexate with Enzoflam-SP Tablet can increase the levels and effects of methotrexate. This can lead to increased risk of side effects.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Enzoflam-SP Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as mouth sores or ulcers, nausea, vomiting, diarrhea, rash, loss of hunger, joint pain or swelling, yellowing of the skin or eyes, dark urine, shortness of breath, a dry cough, paleness, dizziness or fainting, unusual bruising or bleeding, fits, infection, fever, chills, body aches, sore throat or muscle weakness, consult a doctor immediately. Do not stop using medications without a doctor's advice.
DiclofenacNaproxen
Severe
How does the drug interact with Enzoflam-SP Tablet:
Coadministration of Enzoflam-SP Tablet and Naproxen can increase the risk or severity of side effects.

How to manage the interaction:
Taking Enzoflam-SP Tablet and Naproxen together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
DiclofenacDasatinib
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Dasatinib together with Enzoflam-SP Tablet may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Dasatinib but they can be taken together if a doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, red or black, tarry stools, or severe headaches. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Enzoflam-SP Tablet Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, in most of the patients it is safe to take Enzoflam-SP Tablet but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.

Enzoflam-SP Tablet when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,

A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.

Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.

No. Enzoflam-SP Tablet is not indicated for stomach pain. If you have stomach pain refer to doctor as it may be sign of stomach ulcer or gastric bleeding.

Taking excessive alcohol with Enzoflam-SP Tablet can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Enzoflam-SP Tablet .

Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or serratiopeptidase. As, it may lead to overdosage leading to unpleasant side effects. Always consult your doctor before using other medication.

Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • WARFARIN

Special Advise

  • Paracetamol is a component of Enzoflam-SP Tablet which can cause liver injury when in taken in large doses (usually more than 4 g/day). Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
  • Although Enzoflam-SP Tablet provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage of the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissues (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

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