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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Enzoflam-SP Tablet 10's

Enzoflam-SP Tablet 10's belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Enzoflam-SP Tablet 10's is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal. 

You can take Enzoflam-SP Tablet 10's with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition.  Most of the side effects of Enzoflam-SP Tablet 10's do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain etc. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Do not take Enzoflam-SP Tablet 10's if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.

Uses of Enzoflam-SP Tablet 10's

 Pain after any injury, Low back pain, Cervical pain, Spondylitis, Osteoarthritis, Rheumatoid arthritis, etc.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Enzoflam-SP Tablet 10's consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Paracetamol acts as mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue. Together these not only reduce pain and inflammation but also help in faster healing.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Enzoflam-SP Tablet 10's

  • Nausea

  • Stomach Pain

  • Loss of appetite

  • Diarrhoea

  • Stomach upset

  • Indigestion

Drug Warnings

Consumption of alcohol should be avoided during the treatment with Enzoflam-SP Tablet 10's as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Enzoflam-SP Tablet 10's on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Enzoflam-SP Tablet 10's. Use with caution in pregnancy and breastfeeding. Do not self-administer Enzoflam-SP Tablet 10's if you are pregnant or are nursing.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
DiclofenacVorapaxar
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Enzoflam-SP Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
DiclofenacVorapaxar
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.
DiclofenacWarfarin
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.
DiclofenacApixaban
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet and Apixaban may raise the risk of stomach bleeding.

How to manage the interaction:
Although there is a interaction between Enzoflam-SP Tablet and apixaban, but it can be taken if your doctor has advised it. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Do not discontinue any medication without consulting a doctor.
DiclofenacBromfenac
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Enzoflam-SP Tablet and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.
DiclofenacRivaroxaban
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Rivaroxaban together with Enzoflam-SP Tablet may increase the risk of unsual bleeding.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Rivaroxaban can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacValdecoxib
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Valdecoxib with Enzoflam-SP Tablet may increase risk of side effects.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and Valdecoxib but can be taken if prescribed by doctor. However, consult your doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medications without consulting a doctor.
DiclofenacDeferasirox
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet and deferasirox may increase your risk of developing stomach bleeding.

How to manage the interaction:
There may be a possible interaction between Enzoflam-SP Tablet and deferasirox but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience symptoms such as severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, increased or decreased urination, fluid retention, swelling, shortness of breath, muscle cramps, weakness, confusion, and irregular heart rhythm. Do not stop using any medications without first talking to your doctor.
DiclofenacRamucirumab
Severe
How does the drug interact with Enzoflam-SP Tablet:
Co-administration of Enzoflam-SP Tablet and Ramucirumab can cause bleeding and ulcers.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Ramucirumab can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.
DiclofenacIbuprofen
Severe
How does the drug interact with Enzoflam-SP Tablet:
Taking Enzoflam-SP Tablet and ibuprofen can increase the risk of stomach bleeding and ulcers.

How to manage the interaction:
Co-administration of Enzoflam-SP Tablet and Ibuprofen can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.

  • Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.

  • In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.

  • Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Enzoflam-SP Tablet 10's Substitute

Substitutes safety advice
  • Zerodol-SP Tablet 10's

    by Others

    12.51per tablet
  • Signoflam Tablet 10's

    by Others

    14.22per tablet
  • Hifenac-SP Tablet 10's

    by Others

    12.02per tablet
  • Hifenac-D Tablet 10's

    by Others

    12.02per tablet
  • Aceclo Sera Tablet 10's

    by Others

    11.25per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • NIMESULIDE
  • OXYPHENBUTAZONE
  • METAMIZOLE
  • WARFARIN

Special Advise

  • Paracetamol is a component of Enzoflam-SP Tablet 10's which can cause liver injury when in taken in large doses (usually more than 4 g/day). Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
  • Although Enzoflam-SP Tablet 10's provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.

Disease/Condition Glossary

Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage of the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissues (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.

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