Aceclofenac+paracetamol+serratiopeptidase
About
Aceclofenac+paracetamol+serratiopeptidase belongs to the class of drugs known as 'non-steroidal anti-inflammatory drug' (NSAID). It is a fixed-dose combination composed of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac+paracetamol+serratiopeptidase is used in the reduction of pain and inflammation due to bone or soft tissue injury, resolution of postoperative inflammation, oedema (swollen tissue with fluid) and pain. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling in the injured or damaged tissue. Paracetamol acts as a mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase is an enzyme which helps in the breakdown of a protein (fibrin) which is formed as a by-product of the clotted blood at the site of injury. It thus causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue.
Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for a short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage to the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissue (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.
You can take Aceclofenac+paracetamol+serratiopeptidase with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your tablets based on your medical condition. Most of the side effects of Aceclofenac+paracetamol+serratiopeptidase do not require medical attention and gradually resolve over time. Common side effects include nausea, vomiting, indigestion, stomach pain etc. However, if the side effects are persistent, reach out to your doctor.
Try not to stop taking this medicine of your own. Do not take Aceclofenac+paracetamol+serratiopeptidase if you are allergic to painkillers like aspirin, ibuprofen, naproxen, or diclofenac. It is not recommended for use in children. It is advisable not to exceed the recommended dose or duration of treatment.
Uses of Aceclofenac+paracetamol+serratiopeptidase
Medicinal Benefits
Aceclofenac+paracetamol+serratiopeptidase consists of aceclofenac, paracetamol and serratiopeptidase. Aceclofenac works by blocking the action of an enzyme known as cyclo-oxygenase (COX) which causes pain and swelling at the injured or damaged tissue. Paracetamol acts as mild analgesic (pain reducer) and antipyretic (fever reducer) which enhances the pain relief action of aceclofenac. Serratiopeptidase causes thinning of the fluids around the site of injury thereby making fluid drainage smoother in the swollen tissue. Together these not only reduce pain and inflammation but also help in faster healing.
Directions for Use
Storage
Side Effects of Aceclofenac+paracetamol+serratiopeptidase
Nausea
Stomach Pain
Loss of appetite
Diarrhoea
Stomach upset
Indigestion
In-Depth Precautions and Warning
Drug Warnings
Consumption of alcohol should be avoided during the treatment with Aceclofenac+paracetamol+serratiopeptidase as it may lead to an increase in the risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure and liver or kidney disease should not take Aceclofenac+paracetamol+serratiopeptidase on their own. Besides this, it should be avoided during the last trimester of pregnancy, unless there are compelling reasons for doing so. If you have a severe allergy to painkillers like asthma, rhinitis, angioedema (swelling under the skin) or skin rashes, immediately stop taking Aceclofenac+paracetamol+serratiopeptidase. Use with caution in pregnancy and breastfeeding. Do not self-administer Aceclofenac+paracetamol+serratiopeptidase if you are pregnant or are nursing.
Drug Interactions
Drug-Drug Interaction: Drugs containing pain killers (nimesulide, oxyphenbutazone, metamizole), and blood clotting agents (warfarin) should not be taken with Aceclofenac+paracetamol+serratiopeptidase as they may interact.
Drug-Food Interaction: No interaction found.
Drug-Disease Interaction: Inform your doctor if you have peptic ulcer, gastric bleeding, severe heart failure, and high blood pressure before taking Aceclofenac+paracetamol+serratiopeptidase.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeYou are recommended not to consume alcohol along with Aceclofenac+paracetamol+serratiopeptidase to avoid unpleasant side-effects.
Pregnancy
cautionAceclofenac+paracetamol+serratiopeptidase to be taken with caution, specially if you are pregnant. Your doctor may adjust your dose depending upon your conditions, if he/she feels the benefits over weigh the risks.
Breast Feeding
cautionOnly consume Aceclofenac+paracetamol+serratiopeptidase if it has been prescribed by a doctor as the safety data in nursing mothers is lacking. Inform your doctor if you are breastfeeding.
Driving
cautionAceclofenac+paracetamol+serratiopeptidase may affect driving as it causes dizziness.
Liver
cautionAceclofenac+paracetamol+serratiopeptidase to be taken with caution, especially if you have a history of liver diseases/conditions. Dose may have to be adjusted by your doctor.
Kidney
cautionAceclofenac+paracetamol+serratiopeptidase to be taken with caution, especially if you have a history of Kidney diseases/conditions. Dose may have to be adjusted by your doctor.
Children
cautionAceclofenac+paracetamol+serratiopeptidase should not be given to children without prescription of a child specialist. Your doctor will determine the dose of the medicine depending on your child's weight and severity of condition.
Habit Forming
Diet & Lifestyle Advise
Include more glucosamine, chondroitin sulphate, Vitamin D, calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
Do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, low impact aerobic exercises like walking on a treadmill, bike riding and swimming. You can also strengthen your muscle strength by lifting light weights.
In the chronic conditions of arthritis or joint pain try to include fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimum level of chemical called cytokines, which ramp up inflammation.
Your sitting posture is important especially when have pain and inflammation conditions. Try to sit as little as possible, and only for short time (10-15 min). Use back support like rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.
Special Advise
- Paracetamol is a component of Aceclofenac+paracetamol+serratiopeptidase which can cause liver injury when in taken in large doses (usually more than 4 g/day). Concomitant use of alcohol is best avoided as it aggravates the liver toxicity.
Although Aceclofenac+paracetamol+serratiopeptidase provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve best results, it is strongly recommended remaining physically active as much as your condition allows. Adopting a healthy lifestyle coupled with healthy diet containing high proteins, is the mainstay of management of arthritic conditions.
Patients Concern
Disease/Condition Glossary
Pain can be temporary (acute) or lifelong (chronic) in nature. Acute pain is for short time caused by damage to the tissues of the muscle, bone or organs. While, chronic pain lasts for life long caused due to nerve damage, osteoarthritis and dental pain due to damage of the tooth nerve, infection, decay, extraction or injury. There are different types of musculoskeletal pain caused due to soft tissues (muscle, tendon and ligaments) injury. Extreme tissue pain and inflammation caused due to sprains, strains or trauma or post-surgery may require a prolonged amount of time to heal.
FAQs
Yes, in most of the patients it is safe to take Aceclofenac+paracetamol+serratiopeptidase but if it causes any unwanted side effects like diarrhea, vomiting, nausea, please consult your doctor immediately.
Aceclofenac+paracetamol+serratiopeptidase when taken by patients who are allergic to pain-killers or NSAIDs can be harmful. It should also be avoided in person with history of heart failure, kidney or liver disease and stomach ulcers,
A chronic inflammatory disorder affecting many joints, including those in the hands and feet. In rheumatoid arthritis, the body's immune system attacks its own tissue, including joints. In severe cases, it attacks internal organs. Rheumatoid arthritis affects joint linings, causing painful swelling.
Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back. It can spread up to your neck or damage joints in other parts of your body.
No. Aceclofenac+paracetamol+serratiopeptidase is not indicated for stomach pain. If you have stomach pain refer to doctor as it may be sign of stomach ulcer or gastric bleeding.
Taking excessive alcohol with Aceclofenac+paracetamol+serratiopeptidase can cause liver damage. So, it is advisable to avoid or limit intake of alcohol during the treatment with Aceclofenac+paracetamol+serratiopeptidase.
Yes. But ensure pain killers or any other drugs you are taking does not contain paracetamol, aceclofenac or serratiopeptidase. As, it may lead to overdosage leading to unpleasant side effects. Always consult your doctor before using other medication.
