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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Epilan Tablet 150's

Epilan Tablet 150's belongs to the group of neurological medication called 'anticonvulsants or antiepileptic drugs', primarily used to control seizures (fits) in epilepsy. Epilan Tablet 150's is also used to control or prevent seizures during/after brain surgery and also treats trigeminal neuralgia (facial nerve pain). Epilepsy is the central nervous system's disorder characterized by a sudden rush of electrical activity in the brain leading to seizures or fits, unusual behaviour and loss of awareness.

Epilan Tablet 150's contains two antiepileptic medicines: 'Phenobarbital' and 'Phenytoin'. Phenobarbital (also known as phenobarbitone or phenobarb) belongs to the class of drugs called barbiturate anticonvulsants/hypnotics. It works by increasing the activity of GABA (gamma-aminobutyric acid), a neurotransmitter or chemical messenger in the central nervous system. This GABA reduces the abnormal brain activity that occurs during a seizure episode. Phenytoin belongs to the class of drugs called hydantoins. Brain cells or neurons normally work at a certain rate. During a seizure episode, these brain cells are forced to work rapidly in an uncontrolled way. Phenytoin helps prevent the brain cells from such rapid uncontrolled working, thus preventing the brain's abnormal electrical activity during seizures.

Take Epilan Tablet 150's with or without food. You are advised to take Epilan Tablet 150's for as long as your doctor has prescribed it for you, depending on your medical condition. Like all medicines, Epilan Tablet 150's also causes side effects, although not everybody gets them. Common side effects of Epilan Tablet 150's include dizziness, drowsiness, excitation, headache, tiredness, loss of appetite, nausea, vomiting, constipation, spinning sensation and trouble sleeping. Most of these side-effects do not require medical attention and will resolve gradually over treatment. However, if these side-effects persist for a longer time, please seek medical advice.

Please do not skip or stop taking Epilan Tablet 150's midway without consulting your doctor since it may increase seizures. Let your doctor know if you are a pregnant or breastfeeding woman before taking Epilan Tablet 150's. Epilan Tablet 150's should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Epilan Tablet 150's as it might increase the occurrence of side effects. Please inform your doctor about all the prescription and over-the-counter medicines you take before starting Epilan Tablet 150's. 

Uses of Epilan Tablet 150's

Epilepsy (fits).

Directions for Use

Swallow Epilan Tablet 150's as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Epilan Tablet 150's contains two antiepileptic/anticonvulsant medicines, namely: 'Phenobarbital' and 'Phenytoin.' It is used to control seizures (fits) in epilepsy. Epilan Tablet 150's also controls or prevents seizures during/after brain surgery and treats trigeminal neuralgia (facial nerve pain). Phenobarbital (also known as phenobarbitone or phenobarb) is a barbiturate anticonvulsant/hypnotic. It increases GABA activity (gamma-aminobutyric acid), a chemical messenger in the central nervous system. This GABA reduces the abnormal brain activity that occurs during a seizure episode. Phenobarbital does not work for absence seizures. Phenytoin is a hydantoin anticonvulsant medication. It helps prevent the brain cells from rapid uncontrolled working, thus preventing the brain's abnormal electrical activity during seizures. Phenytoin effectively controls jerking movements and muscle spasms during seizure episodes known as grand mal fits. However, Phenytoin does not work for absence (petit mal) seizures.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Inform your doctor if you have a medical history of liver/kidney/heart diseases, hormonal imbalance (Addison's disease), vitamin deficiencies (folic acid, vitamin K, and Vitamin B12), lung disorders (sleep apnoea, chronic obstructive pulmonary disease-COPD), mood disorders (depression, suicidal thoughts), alcohol or drug use and blood disorders like porphyria before starting Epilan Tablet 150's. If you have diabetes, Epilan Tablet 150's should be used with caution since it may affect the blood sugar levels. You may also opt for sugar-free liquid formulations. Please do not stop taking Epilan Tablet 150's midway without consulting your doctor since it may lead to increased seizures. Let your doctor know if you are a pregnant or breastfeeding woman before taking Epilan Tablet 150's. Epilan Tablet 150's should not be given to children unless prescribed by a doctor. Avoid alcohol consumption while taking Epilan Tablet 150's as it might increase the occurrence of side-effects. Epilan Tablet 150's can cause dizziness and affect your ability to drive; hence drive with caution. 

Drug-Drug Interactions

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PhenobarbitalLurasidone
Critical
PhenobarbitalNimodipine
Critical

Drug-Drug Interactions

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PhenobarbitalLurasidone
Critical
How does the drug interact with Epilan Tablet:
Co-administration of Lurasidone with Phenobarbitalmay result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating the illness.

How to manage the interaction:
There is an interaction between Lurasidone and Epilan Tablet,so it is not recommended. You can take it if a doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
PhenobarbitalNimodipine
Critical
How does the drug interact with Epilan Tablet:
When Nimodipine is taken with Epilan Tablet, it may decrease the blood levels of Nimodipine, which may make Nimodipine less effective in treating the condition.

How to manage the interaction:
Taking Nimodipine with Epilan Tablet is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, consult the doctor if you experience any unusual symptoms while taking the therapy. Do not discontinue any medications without consulting the doctor.
PhenobarbitalRilpivirine
Critical
How does the drug interact with Epilan Tablet:
Using Rilpivirine together with Epilan Tablet may significantly reduce the blood levels of rilpivirine, which may make it less effective.

How to manage the interaction:
Taking Rilpivirine with Epilan Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalPirfenidone
Critical
How does the drug interact with Epilan Tablet:
When Pirfenidone is taken with Epilan Tablet, it can decrease the effects of Pirfenidone.

How to manage the interaction:
Taking Pirfenidone with Epilan Tablet is not recommended but can be taken if prescribed by the doctor. Do not discontinue any medication without consulting a doctor.
PhenobarbitalVoriconazole
Critical
How does the drug interact with Epilan Tablet:
Using Voriconazole together with Epilan Tablet may significantly reduce the blood levels of voriconazole.

How to manage the interaction:
Taking Voriconazole with Epilan Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
PhenobarbitalRitonavir
Critical
How does the drug interact with Epilan Tablet:
Taking Epilan Tablet with Ritonavir may significantly reduce the blood levels of ritonavir.

How to manage the interaction:
Taking Epilan Tablet with Ritonavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. If you notice any unusual symptoms consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
PhenobarbitalChlorpromazine
Critical
How does the drug interact with Epilan Tablet:
When Chlorpromazine is taken with Epilan Tablet, can change the drug levels and effects of both medications.

How to manage the interaction:
Taking Chlorpromazine with Epilan Tablet is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience unusual symptoms, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.
PhenobarbitalRanolazine
Critical
How does the drug interact with Epilan Tablet:
When Ranolazine is taken with Epilan Tablet, may significantly reduce the blood levels of Ranolazine, which may make the medication ineffective or less effective.

How to manage the interaction:
Taking Epilan Tablet with Ranolazine can lead to an interaction, consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms. Do not stop taking any medications without consulting a doctor.
PhenobarbitalIsavuconazole
Critical
How does the drug interact with Epilan Tablet:
When Isavuconazole is taken with Epilan Tablet, may decrease the blood levels of Isavuconazole, which may make Isavuconazole less effective.

How to manage the interaction:
Taking Isavuconazole with Epilan Tablet is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.
PhenobarbitalPraziquantel
Critical
How does the drug interact with Epilan Tablet:
Using praziquantel together with Epilan Tablet may significantly reduce the blood levels of praziquantel, which may make the medication less effective.

How to manage the interaction:
Taking Epilan Tablet with Praziquantel is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Following a ketogenic diet (low in carbohydrates and high in fat) is recommended.
  • Meditation, walking, involving in a task and smelling a strong odour are few self-control methods to prevent seizures.
  • Acupuncture therapy may also be helpful.
  • Rest properly, avoid stress by doing meditation or yoga.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
  • Include Vitamin D rich foods like fatty fish, mackerel, tuna, dairy products, orange juice, soy milk, cereals, beef liver, cheese and egg yolks in your diet.
  • Also, it is advised to take folic acid and vitamin K rich foods and supplements during pregnancy.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Epilan Tablet 150's works by controlling the abnormal electrical activity of the brain that causes seizures (fits). Thereby, Epilan Tablet 150's helps in controlling epileptic fits involving spasm of the muscles and jerking.

Phenytoin in Epilan Tablet 150's can make birth control pills less effective. Talk to your doctor about using non-hormonal contraceptives like condoms and diaphragm with spermicide to prevent pregnancy.

Please do not stop taking Epilan Tablet 150's without consulting your doctor on your own as it may lead to increased seizures. Continue taking Epilan Tablet 150's for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Epilan Tablet 150's.

Phenytoin in Epilan Tablet 150's may cause swelling in the gums. Massage your gums, brush and floss your teeth daily, visit your dentist if you experience this problem regularly.

Phenytoin in Epilan Tablet 150's may affect the blood sugar levels. Also, liquid formulations of Epilan Tablet 150's may contain sucrose or sugar. Hence it is advised to consult a doctor before starting Epilan Tablet 150's. Your doctor may also advise sugar-free formulations.

Phenytoin in Epilan Tablet 150's may rarely cause depression/suicidal thoughts. If you experience any of these symptoms, consult your doctor immediately.

Drug-Drug Interactions Checker List

  • DARUNAVIR
  • DELAVIRDINE
  • RILPIVIRINE
  • DOFETILIDE
  • COLESEVELAM
  • QUETIAPINE
  • ORLISTAT
  • PYRIDOXINE (VITB6)
  • SUCRALFATE
  • TELITHROMYCIN
  • AZAPROPAZONE
  • ETRAVIRINE
  • NISOLDIPINE
  • MOLINDONE
  • ITRACONAZOLE
  • VALPROIC ACID

Special Advise

  • Your doctor may advise you to get regular blood tests to test the amount of Epilan Tablet 150's in your blood. 
  • Monitor your blood pressure and sugar levels regularly while using Epilan Tablet 150's.
  • It is advised to get a Vitamin D profile done once in a while using Epilan Tablet 150's.
  • Phenobarbital in Epilan Tablet 150's may lower your folic acid and Vitamin K levels, increasing the risk of spinal cord defects. Please undergo examinations folic acid and Vitamin K to keep a check and use folate and Vitamin K supplements if necessary.

Disease/Condition Glossary

Epilepsy is a central nervous system disorder in which brain activity becomes abnormal, leading to rapid fits/seizure episodes with unusual behaviour and loss of awareness.

Fits/Seizure is a sudden rush of electrical activity in the brain. The main symptom of epilepsy is fits. Epilepsy is of two main types: Generalized seizures (affect the entire brain) and Partial seizures (affect one part of the brain). A mild seizure might be difficult to recognize as it lasts for only a few seconds, during which one lacks awareness. Stronger seizures cause uncontrollable muscle twitches and spasms, lasting for a few seconds to several minutes. Lack of sleep, high fever, stress, bright lights, caffeine, certain medicines, alcohol and skipping meals/overeating are a few of the most common triggers for seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumour and genetic disorders.

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