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About Epitero 50 mg Injection 1's

Epitero 50 mg Injection 1's is an anti-cancer medicine that is used in conjunction with other drugs to treat breast cancer in people who have had tumor removal surgery. Epitero 50 mg Injection 1's is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast).

Epitero 50 mg Injection 1's contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Epitero 50 mg Injection 1's may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, diarrhoea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Epitero 50 mg Injection 1's. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Epitero 50 mg Injection 1's should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines, and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (eg, Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Epitero 50 mg Injection 1's is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Epitero 50 mg Injection 1's is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF.

Uses of Epitero 50 mg Injection 1's

Breast Cancer

Medicinal Benefits

Epitero 50 mg Injection 1's contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. It is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer.

Directions for Use

A trained healthcare professional will administer Epitero 50 mg Injection 1's. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Epitero 50 mg Injection 1's

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection
  • Red discoloration of urine
  • Loss of appetite
  • Mouth sores
  • Tiredness
  • Weight gain
  • Pale skin

Drug Warnings

Epitero 50 mg Injection 1's should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Epitero 50 mg Injection 1's is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Epitero 50 mg Injection 1's is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF. Do not stop receiving Epitero 50 mg Injection 1's without a doctor’s advice, as it can cause serious health conditions. Epitero 50 mg Injection 1's is known to cause severe life-threatening haematological reactions, tissue necrosis, cardiomyopathy, secondary acute myelogenous leukaemia, and severe myelosuppression in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Drug Interactions

Drug-Drug Interactions: Epitero 50 mg Injection 1's may interact with cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), antimicrotubular agents ((paclitaxel, docetaxel), antihistamine (cimetidine), calcium channel blockers (cilnidipine, nifedipine).

Drug-Food Interactions: Avoid smoking and alcohol consumption.

Drug-Disease Interactions: Inform your doctor if you have cardiac problems, liver or kidney disease, heart attack, severe MI, or cardiomyopathy.

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • DOXORUBICIN
  • ABIRATERONE
  • TAMOXIFEN
  • LETROZOLE
  • PACLITAXEL
  • DOCETAXEL
  • CIMETIDINE
  • CILNIDIPINE
  • NIFEDIPINE

Habit Forming

No

Diet & Lifestyle Advise

  • Try to eat more healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.
  • Doing meditation and yoga for some time is very effective in helping cancer patients maintain a healthy attitude and body.

Special Advise

  • Avoid having intercourse while on treatment with Epitero 50 mg Injection 1's.
  • Regular monitoring of complete blood count  (CBC) and liver function (LFT) is important while receiving Epitero 50 mg Injection 1's.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

Consult Doctor

About Epitero 50 mg Injection 1's

Epitero 50 mg Injection 1's is an anti-cancer medicine that is used in conjunction with other drugs to treat breast cancer in people who have had tumor removal surgery. Epitero 50 mg Injection 1's is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast).

Epitero 50 mg Injection 1's contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Epitero 50 mg Injection 1's may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, diarrhoea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Epitero 50 mg Injection 1's. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Epitero 50 mg Injection 1's should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines, and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (eg, Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Epitero 50 mg Injection 1's is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Epitero 50 mg Injection 1's is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF.

Non returnable*
COD available

Online payment accepted

Synonym :

EPIRUBICIN HYDROCHLORIDE

Composition :

EPIRUBICIN-50MG

Manufacturer/Marketer :

Hetero Drugs Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Country of origin

India

Manufacturer/Marketer address

7-2-A2, Hetero Corporate Indl Estates, Sanath Nagar Hyderabad, 500 018
Other Info - EPI0359

FAQs

Epitero 50 mg Injection 1's contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Epitero 50 mg Injection 1's can disrupt a woman's natural menstrual cycle (period) and inhibit sperm production in men. However, you should not presume that you cannot become pregnant or that you cannot make someone else pregnant. It may also harm your foetus. Use reliable methods of birth control while on treatment with Epitero 50 mg Injection 1's.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Unsafe

Alcohol intake might increase the risk of stomach or intestine bleeding. Alcohol consumption is not recommended.

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Pregnancy

Unsafe

Epitero 50 mg Injection 1's is not recommended for use in pregnancy as it may harm your foetus. Hence, if you are pregnant or planning pregnancy, inform your doctor before receiving Epitero 50 mg Injection 1's. Use reliable methods of birth control while on treatment with Epitero 50 mg Injection 1's.

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Breast Feeding

Unsafe

It is not recommended for use in breastfeeding as it may pass into breast milk and harm your infant. Hence, if you are breastfeeding, inform your doctor before receiving Epitero 50 mg Injection 1's. Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Not applicable

Epitero 50 mg Injection 1's does not affect your ability to drive.

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Liver

Caution

Epitero 50 mg Injection 1's should be used with caution in patients with liver impairment. However, this medicine is contraindicated in patients with severe liver disease. If you have a pre-existing or a history of liver disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor. Your doctor may adjust the dose or prescribe a suitable alternative, if necessary, based on your condition.

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Children

Unsafe

Epitero 50 mg Injection 1's is not recommended for use in children, as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF leading to serious side effects.

Uses of Epitero 50 mg Injection 1's

Breast Cancer

Medicinal Benefits

Epitero 50 mg Injection 1's contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. It is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer.

Side Effects of Epitero 50 mg Injection 1's

  • Nausea
  • Abdominal pain
  • Vomiting
  • Dizziness
  • Back pain
  • Pain at the site of injection
  • Red discoloration of urine
  • Loss of appetite
  • Mouth sores
  • Tiredness
  • Weight gain
  • Pale skin

Directions for Use

A trained healthcare professional will administer Epitero 50 mg Injection 1's. Hence, do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Epitero 50 mg Injection 1's should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. Epitero 50 mg Injection 1's is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. Epitero 50 mg Injection 1's is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF. Do not stop receiving Epitero 50 mg Injection 1's without a doctor’s advice, as it can cause serious health conditions. Epitero 50 mg Injection 1's is known to cause severe life-threatening haematological reactions, tissue necrosis, cardiomyopathy, secondary acute myelogenous leukaemia, and severe myelosuppression in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

verifiedApollotooltip
EpirubicinZiprasidone
Critical
EpirubicinEtanercept
Severe

Drug-Drug Interactions

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EpirubicinZiprasidone
Critical
How does the drug interact with Epitero 50 mg Injection:
Using ziprasidone together with Epitero 50 mg Injection can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Epitero 50 mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
EpirubicinEtanercept
Severe
How does the drug interact with Epitero 50 mg Injection:
When Etanercept is used with Epitero 50 mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Epitero 50 mg Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EpirubicinGatifloxacin
Severe
How does the drug interact with Epitero 50 mg Injection:
Taking Epitero 50 mg Injection with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Epitero 50 mg Injection with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EpirubicinBaricitinib
Severe
How does the drug interact with Epitero 50 mg Injection:
Coadministration of baricitinib and Epitero 50 mg Injection can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Epitero 50 mg Injection if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
EpirubicinMifepristone
Severe
How does the drug interact with Epitero 50 mg Injection:
Co-administration of Epitero 50 mg Injection with mifepristone can increase the risk of irregular heart rhythms. Prolonged treatment with Mifepristone may result in low potassium levels.

How to manage the interaction:
Taking Epitero 50 mg Injection with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.
EpirubicinTofacitinib
Severe
How does the drug interact with Epitero 50 mg Injection:
Taking Tofacitinib with Epitero 50 mg Injection may increase the risk of serious infection.

How to manage the interaction:
Co-administration of Epitero 50 mg Injection with Tofacitinib can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain or burning during urination - make sure to call your doctor right away. Do not discontinue any medications without first consulting your doctor.
EpirubicinNilotinib
Severe
How does the drug interact with Epitero 50 mg Injection:
Coadministration of Epitero 50 mg Injection and nilotinib can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Epitero 50 mg Injection and nilotinib together can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
EpirubicinDisopyramide
Severe
How does the drug interact with Epitero 50 mg Injection:
The combined use of Efavirenz and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Efavirenz and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
EpirubicinHaloperidol
Severe
How does the drug interact with Epitero 50 mg Injection:
Co-administration of Epitero 50 mg Injection and Haloperidol can affect the rhythm of the heart.

How to manage the interaction:
Co-administration of Epitero 50 mg Injection and Haloperidol can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
EpirubicinMoxifloxacin
Severe
How does the drug interact with Epitero 50 mg Injection:
Using Moxifloxacin together with Epitero 50 mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Epitero 50 mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heart rhythm, vomiting, dizziness, difficulty breathing, or irregular heartbeat call a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • DOXORUBICIN
  • ABIRATERONE
  • TAMOXIFEN
  • LETROZOLE
  • PACLITAXEL
  • DOCETAXEL
  • CIMETIDINE
  • CILNIDIPINE
  • NIFEDIPINE

Diet & Lifestyle Advise

  • Try to eat more healthy fats, fruits, vegetables and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.
  • Doing meditation and yoga for some time is very effective in helping cancer patients maintain a healthy attitude and body.

Habit Forming

No

Special Advise

  • Avoid having intercourse while on treatment with Epitero 50 mg Injection 1's.
  • Regular monitoring of complete blood count  (CBC) and liver function (LFT) is important while receiving Epitero 50 mg Injection 1's.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

Epitero 50 mg Injection 1's Substitute

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