Esmetil 5 Tablet belongs to a class of antipsychotic medications called phenothiazines used to treat nausea and vomiting during a migraine, schizophrenia, mania, anxiety in the short term, and vertigo (dizziness) due to ear problems such as Meniere’s syndrome. Nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Schizophrenia is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Anxiety is a mental health disorder associated with fear, worry, and excessive nervousness. 

Esmetil 5 Tablet contains Prochlorperazine which works by inhibiting a natural chemical in the brain (dopamine) that stimulates the vomiting center (chemoreceptor trigger zone – CTZ), thereby preventing nausea and vomiting. Besides this, Esmetil 5 Tablet also controls psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania. 

Take Esmetil 5 Tablet as prescribed by your doctor. You are advised to take Esmetil 5 Tablet for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience dry mouth, drowsiness, headache, dizziness, stuffy nose, irritability, missed menstrual periods, impotence (difficulty maintaining an erection), anxiety, skin rash, skin redness, itching, or swelling.  Most of these side effects of Esmetil 5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Do not take Esmetil 5 Tablet if you are known to be allergic to Esmetil 5 Tablet. Esmetil 5 Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Esmetil 5 Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Esmetil 5 Tablet is not recommended for children below 1 year of age. Avoid exposure to direct sunlight while taking Esmetil 5 Tablet as it may cause the skin to be more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumor on the adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Esmetil 5 Tablet.

Esmetil 5 Tablet contains Prochlorperazine that inhibits dopamine secretion that induces the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, Esmetil 5 Tablet prevents nausea and vomiting. Also, Esmetil 5 Tablet control psychotic symptoms in Schizophrenia and has a calming effect on people suffering from anxiety or mania.

• Dry mouth
• Drowsiness
• Headache
• Dizziness
• Stuffy nose
• Irritability
• Missed menstrual periods
• Impotence (difficulty in maintaining an erection)
• Anxiety
• Skin rash
• Skin redness, itching or swelling

Do not take Esmetil 5 Tablet if you are known to be allergic to Esmetil 5 Tablet. Esmetil 5 Tablet should be used with caution in elderly patients above 65 years, as there is an increased risk of adverse effects. Do not take Esmetil 5 Tablet if you are pregnant or breastfeeding as it may cause adverse effects in the baby. Esmetil 5 Tablet is not recommended for children below 1 year of age. Avoid consumption of alcohol with Esmetil 5 Tablet as it may increase adverse effects. You are recommended to avoid contact of Esmetil 5 Tablet with the skin for a long time as it may cause swelling, redness or itching of the skin. Avoid exposure to direct sunlight while taking Esmetil 5 Tablet as it may cause skin to more sensitive to sunlight. If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Esmetil 5 Tablet.

Drug-Drug Interaction: Esmetil 5 Tablet may have interaction with high blood pressure-lowering medicines (metoprolol), opioid analgesics (fentanyl, hydrocodone), laxative (polyethylene glycol 3350), anticonvulsants (pregabalin), antihistamines (diphenhydramine), anti-anxiety drugs (lorazepam, alprazolam), antidepressants (duloxetine), anti-sickness drug (ondansetron).

Drug-Food Interaction: Avoid the intake of alcohol while taking Esmetil 5 Tablet as it may increase side effects and cause breathing difficulties.

Drug-Disease Interaction: If you have fits, depression, diabetes, pheochromocytoma (tumour on adrenal gland), enlarged prostate gland, Parkinson’s disease, dementia (impairment in memory and thinking), myasthenia gravis (muscle weakness), glaucoma,  kidney, liver, heart or thyroid problems, inform your doctor before taking Esmetil 5 Tablet.

• METOPROLOL
• FENTANYL
• HYDROCODONE
• POLYETHYLENE GLYCOL
• PREGABALIN
• DIPHENHYDRAMINE
• LORAZEPAM
• ALPRAZOLAM
• DULOXETINE
• ONDANSETRON

• Eat a healthy diet and a low-fat diet, especially in small portions, as it will be easy for digestion. Avoid eating over sweet food and include more salty food, especially if you have been vomiting.
• If you like to vomit at a specific time, avoid eating your favourite food at that particular time as your taste for that food may get turned off.
• Include more cool beverages in your food like flavoured gelatin, carbonated beverages. And also, when you drink with a stray, sip slowly to avoid swallowing air that may lead to gas or acidity.
• Drink any other liquid at least 30 minutes after eating food.
• If the smell of food makes you feel sick (vomit), do not cook food as it may worsen your condition. Let someone else do cooking or use prepared food from the freezer.
• Avoid consumption of alcohol as it may increase adverse effects.

Avoid exposure to direct sunlight while taking Esmetil 5 Tablet as it may cause the skin to be more sensitive to sunlight.

Nausea and vomiting: Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly.

Anxiety: It is a mental health disorder associated with fear, worry, and excessive nervousness that may interfere with daily activities. The anxiety symptoms include feeling more stress than required for that event and a lack of ability to set aside restlessness and worry.