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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Qmentis Pharma Solutions Llp

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Esohope-L Capsule

Esohope-L Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease occurs when stomach acid frequently flows back into the food pipe (oesophagus); this causes acidity, pain and heartburn. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

Esohope-L Capsule contains Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esohope-L Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

You are advised to take Esohope-L Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, abdominal pain, constipation, diarrhoea, flatulence, nausea and vomiting. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor before taking Esohope-L Capsule if you have a history of gastrointestinal bleeding or intestinal obstruction. On long-term treatment, Esohope-L Capsule may increase the risk of bone fractures. Consult your doctor if you are pregnant or breastfeeding. Esohope-L Capsule may cause drowsiness and dizziness, so drive only if you are alert. Esohope-L Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Esohope-L Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid.

Uses of Esohope-L Capsule

Gastro-oesophageal reflux disease.

Directions for Use

Take Esohope-L Capsule 1hour prior food. Swallow Esohope-L Capsule as a whole with a glass of water, do not chew, or crush it.

Medicinal Benefits

Esohope-L Capsule belongs to a group of medicines called gastrointestinal agents used to treat gastro-oesophageal reflux disease (GERD). Esohope-L Capsule is a combination of two drugs, namely: Esomeprazole (proton pump inhibitor) and Levosulpiride (prokinetic agent). Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esohope-L Capsule helps in preventing acid reflux, thereby providing relief from acidity and heartburn.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Esohope-L Capsule if you are allergic to any of its contents, if you are taking nelfinavir (anti-HIV), if you have a gastrointestinal haemorrhage, mechanical obstruction or perforation, epilepsy, mania, porphyria, or cardiac impairment. Inform your doctor before taking Esohope-L Capsule if you have severe liver or kidney problems; if you are due to have Chromogranin A test; if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Esohope-L Capsule may increase the risk of bone fractures. Do not take Esohope-L Capsule if you are pregnant or breastfeeding. Esohope-L Capsule may cause dizziness and drowsiness, so drive only if you are alert. Esohope-L Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Esohope-L Capsule as it could lead to increased drowsiness and can elevate the production of stomach acid. 

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical

Drug-Drug Interactions

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EsomeprazoleRilpivirine
Critical
How does the drug interact with Esohope-L Capsule:
Esohope-L Capsule may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Esohope-L Capsule with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.
How does the drug interact with Esohope-L Capsule:
Esohope-L Capsule can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Esohope-L Capsule with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Esohope-L Capsule:
Esohope-L Capsule may interfere with the absorption of Acalabrutinib and reduce their efficacy.

How to manage the interaction:
Taking Esohope-L Capsule with Acalabrutinib together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.
How does the drug interact with Esohope-L Capsule:
Esohope-L Capsule decreases the absorption of Pazopanib. This results in reduced efficacy of Pazopanib.

How to manage the interaction:
Although taking Esohope-L Capsule and Pazopanib can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
How does the drug interact with Esohope-L Capsule:
Combining Esohope-L Capsule with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Esohope-L Capsule with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.
EsomeprazoleNelfinavir
Severe
How does the drug interact with Esohope-L Capsule:
Taking nelfinavir with Esohope-L Capsule may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Esohope-L Capsule and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.
How does the drug interact with Esohope-L Capsule:
Esohope-L Capsule reduces the absorption of atazanavir, resulting in reduced efficacy of atazanavir.

How to manage the interaction:
Although there is a possible interaction between Esohope-L Capsule and atazanavir, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Esohope-L Capsule:
Taking gefitinib with Esohope-L Capsule may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Esohope-L Capsule and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Esohope-L Capsule. Do not stop taking any medications without consulting a doctor.
How does the drug interact with Esohope-L Capsule:
Co-administration of methotrexate and Esohope-L Capsule can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Esohope-L Capsule with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Esohope-L Capsule:
Taking tacrolimus with Esohope-L Capsule may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Esohope-L Capsule with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating as it causes acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Esohope-L Capsule is a combination of two drugs, namely: Esomeprazole and Levosulpiride. Esomeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. Levosulpiride works by increasing the stomach and intestinal movement and pressure of the inferior oesophageal (food pipe) sphincter, thereby preventing the backflow of food and acid into the mouth. Together, Esohope-L Capsule helps in preventing acid reflux, thereby providing relief from acidity.

Diarrhoea might be a side-effect of Esohope-L Capsule . Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Do not take Esohope-L Capsule with nelfinavir (a drug used to treat HIV infections). Consult your doctor before taking Esohope-L Capsule with other medicines to rule out unpleasant side-effects.

Esohope-L Capsule contains esomeprazole which might increase the risk of fracture in the wrist, hip or spine. This mainly occurs in people taking Esohope-L Capsule for longer durations. Inform your doctor if you have osteoporosis or if you are taking corticosteroids, your doctor may prescribe calcium and vitamin D supplements.

Esohope-L Capsule may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Esohope-L Capsule .

Dry mouth could be a side-effect of Esohope-L Capsule . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly and chewing sugar-free gum/candy might help in stimulating saliva and thereby prevents drying of the mouth.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • NAPROXEN
  • ATAZANAVIR
  • CLOPIDOGREL
  • WARFARIN
  • CILOSTAZOL
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • ERLOTINIB
  • METHOTREXATE
  • CITALOPRAM
  • IMIPRAMINE
  • CLOMIPRAMINE
  • DULOXETINE
  • DIAZEPAM
  • PHENYTOIN
  • CISAPRIDE
  • DIGOXIN
  • TACROLIMUS
  • RIFAMPICIN

Special Advise

  • Esohope-L Capsule may cause changes in blood tests for checking liver functioning. Inform the person doing the tests that you are taking Esohope-L Capsule .
  • Inform your doctor before taking Esohope-L Capsule if you are due to have Chromogranin A test.

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like GERD, acidity, heartburn and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn and acidity. Symptoms include heartburn, sour or bitter taste in the mouth and difficulty swallowing.

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