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Reviewed By Sunny S , MBBS
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in last 30 days

Composition

EPLERENONE

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About EXENTA 25 TABLET 10'S

EXENTA 25 TABLET 10'S belongs to a class of medicine called 'diuretics' (water pills) primarily used to treat hypertension (high blood pressure). It also maintains the bloodstream's potassium level, removes excess water from the body, and prevents hypertension (high blood pressure) due to oedema (fluid retention). Blood pressure measures the force our heart uses to pump blood to all body parts. Hypertension is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart.

EXENTA 25 TABLET 10'S contains Eplerenone, which is prescribed for the treatment of hypertension. EXENTA 25 TABLET 10'S works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and the heart's workload, making it more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Take EXENTA 25 TABLET 10'S as prescribed by your doctor. Depending upon your medical condition, you are advised to take EXENTA 25 TABLET 10'S for as long as your doctor has prescribed it for you. In some cases, you may experience dehydration, electrolyte disturbances (calcium, magnesium, and sodium), constipation, itching, and increased uric acid. Most of these side effects of EXENTA 25 TABLET 10'S do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking a EXENTA 25 TABLET 10'S of your own, as doing so may raise your blood pressure, thereby increasing the risk of heart disease and stroke. Inform your doctor if you have any kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2, and patients with nil urine output (anuria). If you are pregnant or breastfeeding, please tell your doctor so that the dosage of EXENTA 25 TABLET 10'S can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to the EXENTA 25 TABLET 10'S. Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling. Please take EXENTA 25 TABLET 10'S at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take EXENTA 25 TABLET 10'S along with lithium to prevent serious side effects.

Uses of EXENTA 25 TABLET 10'S

Hypertension (high blood pressure), Edema

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

EXENTA 25 TABLET 10'S primarily used to treat hypertension (high blood pressure) and heart failure. It also treats edema (reduces swelling) caused due to other conditions. EXENTA 25 TABLET 10'S works by increasing the amount of urine passing from the kidneys. It effectively reduces excess fluid levels in the body and reduces the heart's workload, and makes the heart more efficient at pumping blood throughout the body. Thus, it also helps lower high blood pressure, reducing the chances of any future heart attack, stroke, or angina (chest pain) in the future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of EXENTA 25 TABLET 10'S

  • Dizziness
  • Nausea
  • Dizziness
  • Headache
  • Cough
  • Increased creatinine and potassium in the blood
  • Fatigue

Drug Warnings

EXENTA 25 TABLET 10'S should not be given to the people allergic to EXENTA 25 TABLET 10'S, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease (with creatinine clearance less than 30 mL/min), liver disease, high serum potassium (hyperkalemia), diabetes mellitus type 2 and patients with nil urine output (anuria), pregnant women, planning to get pregnant and breastfeeding women. EXENTA 25 TABLET 10'S can pass into breast milk, but its effect on the baby is unknown, so it is better to tell your doctor if you are taking EXENTA 25 TABLET 10'S and breastfeeding. Dehydration with electrolyte and acid-base disturbances must be corrected before using EXENTA 25 TABLET 10'S. Do not take extra potassium supplements or potassium-rich foods such as bananas and broccoli with EXENTA 25 TABLET 10'S. It may lead to an excessive increase in blood potassium levels (hyperkalemia). Please take EXENTA 25 TABLET 10'S at least 4 hours before sleeping to avoid frequent urination at night. Also, do not take EXENTA 25 TABLET 10'S along with lithium to prevent serious side effects.

Drug-Drug Interactions

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EplerenoneSpironolactone
Critical
EplerenonePosaconazole
Critical

Drug-Drug Interactions

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EplerenoneSpironolactone
Critical
How does the drug interact with Exenta 25 Tablet:
Combining Exenta 25 Tablet with Spiranolactone may significantly increase potassium levels in the blood which can lead to kidney issues and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between spironolactone and Exenta 25 Tablet, it is not recommended as it can lead to an interaction. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenonePosaconazole
Critical
How does the drug interact with Exenta 25 Tablet:
Coadministration of posaconazole with Exenta 25 Tablet can increase the blood levels of Exenta 25 Tablet. This can increase the risk of serious side effects, including hyperkalemia (high blood potassium).

How to manage the interaction:
Although there is an interaction between posaconazole and Exenta 25 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EplerenoneKetoconazole
Critical
How does the drug interact with Exenta 25 Tablet:
Coadministration of Ketoconazole with Exenta 25 Tablet can increase the levels of blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking ketoconazole with Exenta 25 Tablet is not recommended as it can result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenoneSaquinavir
Critical
How does the drug interact with Exenta 25 Tablet:
Co-administration of EPELENONE and SAQUINAVIR may significantly increase the blood levels and side effects of Exenta 25 Tablet. This can increase the risk of serious side effects like high blood potassium, which in severe cases can lead to kidney failure, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Taking saquinavir and Exenta 25 Tablet together is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the doctor's advice.
EplerenoneItraconazole
Critical
How does the drug interact with Exenta 25 Tablet:
The blood levels and effects of Exenta 25 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Although there is a possible interaction between Exenta 25 Tablet and Itraconazole, it is not recommended; they can be taken if prescribed by a doctor. Consult a doctor if you have complications such as hyperkalemia (high blood potassium), which in extreme circumstances can result in kidney problems, muscle paralysis, and an irregular heartbeat. Without first consulting your doctor, never stop taking medicines.
EplerenoneNefazodone
Critical
How does the drug interact with Exenta 25 Tablet:
Coadministration of Nefazodone with Exenta 25 Tablet can increase the levels of Exenta 25 Tablet in the body.

How to manage the interaction:
Taking Nefazodone with Exenta 25 Tablet together is not recommended as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without a doctor's advice.
EplerenonePotassium citrate
Critical
How does the drug interact with Exenta 25 Tablet:
Taking Exenta 25 Tablet with Potassium citrate may significantly increase potassium levels in the blood which can lead to kidney issues, muscle paralysis (loss of muscle function) and irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Potassium citrate and Exenta 25 Tablet, you can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or irregular heartbeat. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenonePotassium chloride
Critical
How does the drug interact with Exenta 25 Tablet:
Using Exenta 25 Tablet together with Potassium chloride may significantly increase potassium levels in the blood.

How to manage the interaction:
Taking potassium chloride with Exenta 25 Tablet is not recommended. You can take these medicines if prescribed by a doctor. Consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or an irregular heartbeat, consult the doctor immediately. It is essential to maintain proper fluid intake while taking these medications. Do not discontinue any medications without a doctor's advice.
EplerenoneClarithromycin
Critical
How does the drug interact with Exenta 25 Tablet:
Co-administration of Exenta 25 Tablet and Clarithromycin may significantly increase the blood levels and effects of Exenta 25 Tablet.This may increase the risk or severity of side effects like high blood potassium which can lead to kidney damage and irregular heart rate.

How to manage the interaction:
Taking Clarithromycin with Exenta 25 Tablet is not recommended as it can lead to interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without the Doctor's advice.
EplerenoneRitonavir
Critical
How does the drug interact with Exenta 25 Tablet:
Co-administration of Exenta 25 Tablet and Ritonavir may significantly increase the blood levels of Exenta 25 Tablet.

How to manage the interaction:
Taking Ritonavir and Exenta 25 Tablet together is not recommended as it can lead to an interaction. However, it can be taken if a doctor advises it. If you experience any unusual symptoms like headaches, irritation, confusion, edema (swelling caused by too much fluid accumulation), weakness, palpitations, or constipation, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are highly antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • Elevate your legs or the swollen area on a chair or pillow.
  • Avoid standing or sitting for extended periods.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

DIURETIC

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ASPIRIN
  • WARFARIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN
  • ITRACONAZOLE
  • KETOCONAZOLE
  • RITONAVIR
  • NELFINAVIR
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • LITHIUM

Special Advise

  • Treatment with EXENTA 25 TABLET 10'S requires regular monitoring of serum potassium and creatinine level.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Monitor your blood sugar level daily and if there is too much fluctuation, then immediately contact your doctor.

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

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