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Written By Divya L , PharmaD
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Fluconazole 200 mg/100 ml I.V.

Fluconazole 200 mg/100 ml I.V. belongs to the class of medicines called 'antifungals' used to treat a broad range of infections caused by fungi and yeast. A fungal infection is caused when a fungus invades and affects any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood.

Fluconazole 200 mg/100 ml I.V. contains ‘Fluconazole’ that kills or prevents fungi or yeast growth by inhibiting an enzyme responsible for its normal fat metabolism. This interferes with the formation of the fungal cell membrane. As a result, fungal or yeast cells get killed or their growth is minimized.

Fluconazole 200 mg/100 ml I.V. may cause common side effects like headache, diarrhoea, nausea, stomach upset, dizziness, stomach pain, and altered food tastes. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Inform your doctor if you are allergic to any of the components in Fluconazole 200 mg/100 ml I.V.. Let your doctor know if you have any liver, kidney or heart problems before starting Fluconazole 200 mg/100 ml I.V.. Pregnant and breastfeeding women should consult their doctor before starting Fluconazole 200 mg/100 ml I.V.. It is advised to avoid alcohol intake while using Fluconazole 200 mg/100 ml I.V. to prevent any undesirable effects.

Uses of Fluconazole 200 mg/100 ml I.V.

Fungal infections.

Directions for Use

Fluconazole 200 mg/100 ml I.V. will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Fluconazole 200 mg/100 ml I.V. is used to treat various fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), oesophagal candidiasis (candida esophagitis), candida infections (urinary tract infections, peritonitis), and cryptococcal meningitis. Besides this, Fluconazole 200 mg/100 ml I.V. is also used to prevent candidiasis and coccidioidomycosis in patients who receive cancer or radiation treatment while undergoing bone marrow transplantation. Fluconazole 200 mg/100 ml I.V. is effective in treating soft tissue and pulmonary infections when compared to other azole antifungal drugs. It works by killing the fungus/yeast and preventing its growth by inhibiting the fungal cell membrane formation.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fluconazole 200 mg/100 ml I.V.

  • Headache
  • Diarrhoea
  • Nausea
  • Stomach upset
  • Dizziness
  • Stomach pain
  • Altered food tastes

Drug Warnings

Please inform your doctor if you use any prescription, or non-prescription medicines, including vitamin and herbal supplements before using Fluconazole 200 mg/100 ml I.V.. Do not use Fluconazole 200 mg/100 ml I.V. if you are allergic to any of its components. Let your doctor know if you have any liver, kidney, or heart problems, a weakened immune system, diabetes, cancer, or low blood magnesium or potassium levels. Pregnant or lactating women should consult the doctor before taking Fluconazole 200 mg/100 ml I.V.. Do not drive or operate machinery if you experience dizziness or other side effects that may affect your mental ability to drive. Avoid alcohol consumption along with Fluconazole 200 mg/100 ml I.V. to avoid undesirable effects.

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
FluconazoleEliglustat
Critical

Drug-Drug Interactions

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FluconazoleErythromycin
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking Fluconazole 200 mg/100 ml I.V. with Erythromycin can increase the risk of heart rhythm problems.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Erythromycin together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleEliglustat
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Eliglustat and Fluconazole 200 mg/100 ml I.V. are taken together, Fluconazole 200 mg/100 ml I.V. can significantly increase the blood levels of eliglustat.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Eliglustat together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, shortness of breath, slow heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
FluconazoleLomitapide
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Lomitapide is taken with Fluconazole 200 mg/100 ml I.V., may increase the blood levels of lomitapide.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Lomitapide together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
FluconazoleAstemizole
Critical
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
When Astemizole is taken with Fluconazole 200 mg/100 ml I.V., the body's ability to break down Astemizole may be reduced.

How to manage the interaction:
Taking Fluconazole 200 mg/100 ml I.V. with Astemizole can lead to an interaction, please consult a doctor before taking it. Do not discontinue the medications without of consulting a doctor.
FluconazoleRuxolitinib
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Ruxolitinib with Fluconazole 200 mg/100 ml I.V. may increase the blood levels of Ruxolitinib.

How to manage the interaction:
Although there is a possible interaction, Fluconazole 200 mg/100 ml I.V. can be taken with Ruxolitinib if prescribed by the doctor. Consult the doctor if you experience signs and symptoms such as paleness, tiredness, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches, or other flu-like symptoms. Do not discontinue the medications without consulting a doctor.
FluconazoleBosutinib
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking bosutinib with Fluconazole 200 mg/100 ml I.V. can increase the blood levels of bosutinib. This can increase side effects such as nausea, vomiting, abdominal pain, and diarrhea.

How to manage the interaction:
Although there is a possible interaction, Fluconazole 200 mg/100 ml I.V. can be taken with Bosutinib if prescribed by the doctor. However, consult your doctor if you experience fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
FluconazoleGlimepiride
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Fluconazole 200 mg/100 ml I.V. may increase the blood levels and effects of Glimepiride may cause low blood glucose.

How to manage the interaction:
Although there is a possible interaction, glimepiride can be taken with Fluconazole 200 mg/100 ml I.V. if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
FluconazoleTeriflunomide
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Co-administration of Teriflunomide with Fluconazole 200 mg/100 ml I.V. may increase the risk of liver problems.

How to manage the interaction:
There may be a possibility of interaction between Fluconazole 200 mg/100 ml I.V. and Teriflunomide, but it can be taken if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: liver problems, fever, feeling cold, joint discomfort, swelling, bruising, skin irritation, itching, not feeling hungry, tiredness, feeling sick, throwing up, stomach ache, dark urine, liver harm, or bleeding. Do not stop using any medications without a doctor's advice.
FluconazoleDicoumarol
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking Fluconazole 200 mg/100 ml I.V. with Dicumarol may increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction, Fluconazole 200 mg/100 ml I.V. can be taken with Dicumarol if prescribed by the doctor. Consult the doctor if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not discontinue the medications without a doctor's advice.
FluconazoleLemborexant
Severe
How does the drug interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Taking lemborexant with Fluconazole 200 mg/100 ml I.V. may increase the blood levels of lemborexant. This may increase the risk of side effects.

How to manage the interaction:
There may be a possibility of interaction between Lemborexant and Fluconazole 200 mg/100 ml I.V., but it can be taken if prescribed by a doctor. However, if you experience depression, abnormal sleep behaviors, worsening of depression, changes in heartbeat, or headache, contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Use mild soap while taking baths and prefer warm baths.
  • Avoid harsh products on your skin.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Avoid or limit the intake of alcohol and caffeine.
  • Take non-starchy vegetables and gluten-free foods.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Fluconazole 200 mg/100 ml I.V. Substitute

Substitutes safety advice
  • Forcan-200 Tablet 4's

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  • Syscan-200 Capsule 4's

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    17.55per tablet
  • Onecan 200 mg Tablet 4's

    by AYUR

    17.55per tablet
  • Flucos 200 Tablet 6's

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    17.55per tablet

Author Details

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Drug-Diseases Interactions

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FLUCONAZOLE-200MGOther diseases of liver
Severe
FLUCONAZOLE-200MGOther cardiac arrhythmias
Moderate

Drug-Diseases Interactions

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FLUCONAZOLE-200MGOther diseases of liver
Severe
How does the disease interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Hepatotoxicity has only sometimes been linked to the usage of Fluconazole 200 mg/100 ml I.V.. There have been cases of reversible idiosyncratic hepatitis, cholestasis, and deadly fulminant hepatic failure; the latter generally affects people with substantial underlying medical disorders who are also taking several concurrent drugs. Patients with pre-existing hepatic problems should have periodic liver function tests done, especially during prolonged medication. If liver enzyme levels continue to rise or worsen, treatment should be stopped.

How to manage the interaction:
In patients with preexisting liver abnormalities, particularly during prolonged therapy, liver function tests should be done regularly. Treatment should be withdrawn if persistent elevations or worsening of liver enzyme levels occur.
FLUCONAZOLE-200MGOther cardiac arrhythmias
Moderate
How does the disease interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
The QT interval on the ECG has been shown to be prolonged by some azole antifungals. During postmarketing experience, there have been a few isolated incidences of QT prolongation and torsade de pointes; these reports typically involved critically ill patients with a number of complicating risk factors, including structural cardiac disease, electrolyte problems, and concurrent medicines. Patients with illnesses that could cause proarrhythmic symptoms should take these medications cautiously. It is best to avoid using drugs that could potentially enhance the risk of cardiotoxicity concurrently.

How to manage the interaction:
It should be administered with caution to patients with heart problems. Concomitant use with other medications that have potential to increase the risk of cardiotoxicity should be avoided.
FLUCONAZOLE-200MGCare involving dialysis
Moderate
How does the disease interact with Fluconazole 200 mg/100 ml I.V. 200 mg/100 ml I.V.:
Hemodialysis effectively removes Fluconazole 200 mg/100 ml I.V. from the body. Following three hours of dialysis, it has been demonstrated that plasma levels of Fluconazole 200 mg/100 ml I.V. decrease by 50%. After hemodialysis, Fluconazole 200 mg/100 ml I.V. should be taken.

How to manage the interaction:
Fluconazole 200 mg/100 ml I.V. should be administered after hemodialysis.

Drug-Drug Interactions Checker List

  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • PHENYTOIN
  • CYCLOSPORIN
  • TACROLIMUS
  • RIFAMPIN
  • THEOPHYLLINE
  • RIFABUTIN

Special Advise

  • Regular liver function tests are advised while on treatment with Fluconazole 200 mg/100 ml I.V..
  • Inform your doctor immediately if you develop rashes or lesions while on treatment with Fluconazole 200 mg/100 ml I.V..

Disease/Condition Glossary

Fungal infection: It occurs when a fungus enters, infects, and multiplies in the body. Fungi can live in water, soil, air, and plants. Fungi affect any part of the body, including the mouth, throat, oesophagus, lungs, bladder, genital area, and blood. Mild fungal skin infections are common and can cause rashes. Fungal infections affecting body organs like the lungs can cause flu or tuberculosis. Some fungal diseases like cryptococcal meningitis and blood infections can be fatal.

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