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  3. Fosa 150Mg Inj

Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
COD available

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Composition :

APREPITANT-150MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Fosa 150Mg Inj

Fosa 150Mg Inj belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in patients six months of age and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Fosa 150Mg Inj contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking neurokinin-1 receptors (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Fosa 150Mg Inj will be administered by a healthcare professional; do not self-administer. In some cases, Fosa 150Mg Inj may cause common side effects such as weakness, tiredness, diarrhoea, urinary tract infection, pain in arms and legs, or indigestion. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen. 

If you are allergic to Fosa 150Mg Inj or any other medicines, please tell your doctor. Fosa 150Mg Inj is not recommended for children below six months of age. If you are pregnant or breastfeeding, please inform your doctor before taking Fosa 150Mg Inj. Drive only if you are alert after receiving Fosa 150Mg Inj. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Fosa 150Mg Inj. 

Uses of Fosa 150Mg Inj

Chemotherapy-induced nausea and vomiting

Directions for Use

Fosa 150Mg Inj will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Fosa 150Mg Inj contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in patients six months of age and above.

Storage

Keep Fosa 150Mg Inj out of the sight and reach of children.
Side effects of Fosa 150Mg Inj
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Drug Warnings

If you are allergic to Fosa 150Mg Inj or any other medicines, please tell your doctor. Fosa 150Mg Inj is not recommended for children below 6 months of age. If you are pregnant or breastfeeding, please inform your doctor before taking Fosa 150Mg Inj. Drive only if you are alert after receiving Fosa 150Mg Inj. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Fosa 150Mg Inj. If you are using warfarin (blood thinner), your doctor may recommend blood tests after you receive Fosa 150Mg Inj to check your blood clotting.

Drug-Drug Interactions

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FosaprepitantTerfenadine
Critical
FosaprepitantAstemizole
Critical

Drug-Drug Interactions

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FosaprepitantTerfenadine
Critical
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Terfenadine, it can lower the rate at which Fosa 150Mg Inj is broken down and increases its levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj and Terfenadine together is generally avoided as it can show an interaction, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms like Chest discomfort, Shortness of breath, Weakness, or palpitations, it's important to call your doctor right away - they can be serious heart problems. Do not discontinue any medications without consulting a doctor.
FosaprepitantAstemizole
Critical
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Astemizole can increase the levels of Astemizole in the body. This increases the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosa 150Mg Inj with Astemizole together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantEliglustat
Critical
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Eliglustat, can increase Eliglustat levels in the body. This can increase the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Fosa 150Mg Inj and Eliglustat, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantLomitapide
Critical
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Lomitapide, it can increase the levels of Lomitapide. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Lomitapide together is not recommended as it can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms - diarrhea, nausea, vomiting, pain, discomfort, indigestion, constipation, liver damage, fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, dark colored urine, bleeding or vomiting - make sure to call your doctor right away. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Cisapride can increase the levels of Cisapride in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Cisapride together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantFlibanserin
Critical
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Flibanserin can increase the levels of Flibanserin in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Flibanserin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of headaches, irritation, confusion, edema, fatigue, palpitations, or constipation, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Fosa 150Mg Inj:
When Pimozide is taken with Fosa 150Mg Inj, it can increase the Pimozide levels in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Fosa 150Mg Inj with Pimozide is not recommended, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, prolonged diarrhea, or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
FosaprepitantHydrocodone
Severe
How does the drug interact with Fosa 150Mg Inj:
Coadministration of Fosa 150Mg Inj with Hydrocodone can increase the levels of Hydrocodone in the body. This increases the risk or severity of side effects.

How to manage the interaction:
There may be a possibility of interaction between Fosa 150Mg Inj and Hydrocodone, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, fainting, confusion, excessive drowsiness, slow heart rate, or shallow or difficult breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Fosa 150Mg Inj:
When Fosa 150Mg Inj is taken with Ranolazine, can increase the levels of Ranolazine in the body. This can increase the risk or severity of side effects like irregular heart rhythms.

How to manage the interaction:
Taking Fosamprepitant with Ranolazine can lead to an interaction, please consult a doctor before taking it. They can be taken together if advised by a doctor. However, contact a doctor if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop taking any medications without consulting a doctor.
FosaprepitantHalofantrine
Severe
How does the drug interact with Fosa 150Mg Inj:
Taking Fosa 150Mg Inj and Halofantrine can increase the levels of Halofantrine and increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Fosa 150Mg Inj and Halofantrine, you can take these medicines together if prescribed by your doctor. Your doctor can suggest other options that do not interact with certain medications. When taking halofantrine, it is important to be cautious and closely monitored if you are also taking certain medications like itraconazole, ketoconazole, or clarithromycin. Before starting halofantrine, it is recommended to get an ECG and have your heart monitored during and after treatment. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, skinless poultry, lean meats, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Side Effects of Fosa 150Mg Inj

  • Weakness
  • Tiredness
  • Diarrhoea
  • Urinary tract infection
  • Pain in arms and legs
  • Indigestion

Habit Forming

No

Therapeutic Class

ANTIEMETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Fosa 150Mg Inj works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines.

Fosa 150Mg Inj may cause weakness as a common side effect. However, if the weakness persists or worsens, consult your doctor.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Fosa 150Mg Inj. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Fosa 150Mg Inj and for up to 1 month after using Fosa 150Mg Inj.

Drug-Drug Interactions Checker List

  • PIMOZIDE

Disease/Condition Glossary

Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.

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