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  3. FOSOLIN 750MG INJECTION 10ML

FOSOLIN 750MG INJECTION 10ML, Pack of 1
FOSOLIN 750MG INJECTION 10ML, Pack of 1
FOSOLIN 750MG INJECTION 10ML, Pack of 1
FOSOLIN 750MG INJECTION 10ML, Pack of 1
FOSOLIN 750MG INJECTION 10ML, Pack of 1
FOSOLIN 750MG INJECTION 10ML, Pack of 1
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Synonym :

FOSPHENYTOIN

Composition :

FOSPHENYTOIN SODIUM-750MG

Manufacturer/Marketer :

Zydus Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About FOSOLIN 750MG INJECTION

FOSOLIN 750MG INJECTION belongs to the class of drugs known as anticonvulsants. It is used to treat generalized tonic-clonic seizures as well as to treat and prevent seizures that may occur during or after brain or nervous system operations. A tonic-clonic seizure, often called a grand mal seizure, is characterized by a loss of consciousness and strong muscle contractions. Seizures are uncontrollable bursts of electrical activity in the brain.

FOSOLIN 750MG INJECTION contains 'Fosphenytoin Sodium' that decreases the brain's abnormal electrical activity.

A healthcare professional will administer FOSOLIN 750MG INJECTION. In some cases, FOSOLIN 750MG INJECTION may cause common side effects such as loss of coordination, confusion, dizziness, weakness, dysarthria (slurred speech), dry mouth, headache, vision problems and constipation. Most of these side effects do not require medical attention and will resolve gradually. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before using the FOSOLIN 750MG INJECTION, inform your doctor about your medical conditions, sensitivities, and all the ongoing medications. Continue using FOSOLIN 750MG INJECTION for as long as your doctor has prescribed. Treatment with FOSOLIN 750MG INJECTION should be gradually withdrawn, so do not stop taking FOSOLIN 750MG INJECTION without consulting your doctor. Consult your doctor immediately if you observe any behavioural changes or suicidal tendencies. FOSOLIN 750MG INJECTION may impair your ability to judge, think clearly, or respond quickly. Do not drive, operate heavy machinery, or engage in risky activities. Avoid consuming alcohol with FOSOLIN 750MG INJECTION as it could increase drowsiness and dizziness. Breastfeeding is not recommended for women receiving fosphenytoin sodium injections. It is recommended not to use while pregnant, so inform your doctor if you are pregnant or expect pregnancy.

Uses of FOSOLIN 750MG INJECTION

Tonic-clonic seizures

Directions for Use

FOSOLIN 750MG INJECTION will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

FOSOLIN 750MG INJECTION belongs to the group of medicines called anticonvulsants. It is used to treat primary generalized tonic-clonic seizures (A tonic-clonic seizure, previously known as a grand mal seizure, causes a loss of consciousness and violent muscle contractions) and to treat and prevent seizures that may begin during or after surgery to the brain or nervous system. Fosphenytoin injection may also be used to control certain types of seizures in people who cannot take oral phenytoin.

Storage

Store in a cool and dry place away from sunlight
Side effects of Fosolin 750mg Injection 10ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Drug Warnings

Do not take FOSOLIN 750MG INJECTION if you are allergic to any of its contents. Inform your doctor if you have had heart failure, low blood pressure, irregular heart rhythms, or heart block. Do not drive or operate heavy machinery as FOSOLIN 750MG INJECTION may impair your ability to drive or operate machinery. Avoid consumption of alcohol as it may cause increased dizziness/drowsiness and affect the concentration of Fosphenytoin in the blood. While receiving the fosphenytoin injection or afterwards, you may encounter acute or life-threatening low blood pressure or abnormal heart rhythms. If you experience any of the symptoms, contact your doctor right away. It is recommended not to be used in pregnant women and nursing mothers. So inform your doctor if you are pregnant or breastfeeding women before receiving this medicine.

Drug-Drug Interactions

verifiedApollotooltip
FosphenytoinLurasidone
Critical
FosphenytoinAxitinib
Severe

Drug-Drug Interactions

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FosphenytoinLurasidone
Critical
How does the drug interact with Fosolin 750mg Injection 10ml:
Lurasidone co-administration with Fosolin 750mg Injection 10ml may result in significantly lower blood levels of lurasidone, making the medication less effective or ineffective in treating your illness.

How to manage the interaction:
Although there is an interaction between Lurasidone and Fosolin 750mg Injection 10ml, you can take it if your doctor has prescribed it. Consult a doctor if you experience any unusual symptoms. Do not discontinue any medications without consulting a doctor.
FosphenytoinAxitinib
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
Fosolin 750mg Injection 10ml may decrease the blood levels of Axitinib, which may make Axitinib less effective in treating your condition

How to manage the interaction:
Co-administration of Axitinib with Fosolin 750mg Injection 10ml can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
FosphenytoinAripiprazole
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Aripiprazole and Fosolin 750mg Injection 10ml are taken together, can reduce the levels of Aripiprazole levels in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although taking Aripiprazole and Fosolin 750mg Injection 10ml together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
FosphenytoinVorapaxar
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Vorapaxar is taken with Fosolin 750mg Injection 10ml, it can cause the metabolism of Vorapaxar to speed up. This can decrease the treatment outcomes.

How to manage the interaction:
Co-administration of Fosolin 750mg Injection 10ml with Vorapaxar can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having symptoms like throbbing or cramping pain, swelling, redness, and warmth in a leg or arm, it's important to let your doctor know right away. Do not stop using any medications without first talking to your doctor.
FosphenytoinTenofovir disoproxil
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Tenofovir disoproxil is taken with Fosolin 750mg Injection 10ml, the amount of Tenofovir disoproxil in the blood may decrease.

How to manage the interaction:
Taking Fosolin 750mg Injection 10ml with Tenofovir disoproxil together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
FosphenytoinDarunavir
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Fosolin 750mg Injection 10ml is taken with Darunavir can reduce the levels of Darunavir which can lead to low treatment outcomes.

How to manage the interaction:
Taking Darunavir with Fosolin 750mg Injection 10ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without a doctor's advice.
FosphenytoinFluconazole
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Fosolin 750mg Injection 10ml is taken with Fluconazole, may affect the Fosolin 750mg Injection 10ml levels in your body which can increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Fluconazole with Fosolin 750mg Injection 10ml can possibly result in an interaction, but it can be taken if a doctor has advised it. Watch out for any signs of dizziness, fatigue, weakness, having trouble seeing, nausea, vomiting, or having trouble moving your muscles. If you notice any of these symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
FosphenytoinPraziquantel
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Praziquantel is taken with Fosolin 750mg Injection 10ml, it can cause the body to break down Praziquantel faster. This can lead to low treatment outcomes.

How to manage the interaction:
There may be a possibility of interaction between Fosolin 750mg Injection 10ml and Praziquantel, but it can be taken if prescribed by a doctor. If you experience symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FosphenytoinStiripentol
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
When Fosolin 750mg Injection 10ml is taken with Stiripentol, it can slow down the body's metabolism and may alter the blood levels of both medications. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Stiripentol with Fosolin 750mg Injection 10ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, rapid heartbeat, difficulty concentrating, and motor impairment, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
FosphenytoinCaspofungin
Severe
How does the drug interact with Fosolin 750mg Injection 10ml:
Coadministration of Caspofungin and Fosolin 750mg Injection 10ml can reduce the levels of Caspofungin in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Although there is a possible interaction between Caspofungin and Fosolin 750mg Injection 10ml, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for people with epilepsy. This diet helps utilise fat instead of glucose to generate energy.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation and yoga can help lower stress, decrease pain sensitivity and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.
  • Have a seizure response plan, which helps those around you know what to do.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 20, 2024 | 1:17 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

FOSOLIN 750MG INJECTION contains 'Fosphenytoin Sodium' that decreases the brain's abnormal electrical activity.

One of the most prevalent side effects of FOSOLIN 750MG INJECTION is dysarthria (slurred speech). It normally does not require medical attention and resolves on its own. However, if the illness persists or worsens, please seek medical attention.

FOSOLIN 750MG INJECTION frequently causes vision difficulties and uncontrollable eye movements. It normally does not require medical care and resolves on its own over time. However, if the issue persists or worsens, consult a doctor.

Fosphenytoin is not recommended for patients who have a history of hypersensitivity to fosphenytoin or its constituents, as well as phenytoin or other hydantoins.

Drug-Drug Interactions Checker List

  • APREMILAST
  • APIXABAN
  • BOSUTINIB
  • CIMETIDINE
  • DELAVIRDINE
  • DOLUTEGRAVIR
  • FLUCONAZOLE
  • HALOPERIDOL
  • LEFLUNOMIDE
  • METHADONE

Special Advise

  • Consult your doctor immediately if you have suicidal thoughts such as harming or killing yourself.

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, are a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, tongue biting, confusion, and loss of consciousness.

Tonic-clonic seizure: A tonic-clonic seizure, previously known as a grand mal seizure, causes a loss of consciousness and violent muscle contractions.

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