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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Composition :

FOSFOMYCIN-4GM

Manufacturer/Marketer :

Pollen Healthcare Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Fospol Injection 4 gm

Fospol Injection 4 gm belongs to a class of drugs called antibiotics used in the treatment of bacterial infections. Fospol Injection 4 gm is used to treat bacterial meningitis (infection of membranes protecting the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues below the skin. Bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly.

Fospol Injection 4 gm contains Fosfomycin which works by inhibiting the formation of the bacterial cell walls (a protective covering) that is necessary for their survival. Thereby killing bacteria. Also, Fospol Injection 4 gm decreases the attachment of bacteria to cells lining the urinary bladder.

Fospol Injection 4 gm will be administered by a healthcare professional. Do not self-administer. You may sometimes experience gastrointestinal disturbances, taste disturbances, or injection site reactions. Most of these side effects of Fospol Injection 4 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Fosfomycin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Fospol Injection 4 gm. Fospol Injection 4 gm could be used in children if prescribed by a doctor; the dose depends on the child’s age and weight. If you have experienced diarrhoea after receiving or taking antibiotics, inform your doctor before taking Fospol Injection 4 gm. If you have kidney problems or are undergoing dialysis, inform your doctor as the dose may be reduced. 

Uses of Fospol Injection 4 gm

Bacterial infections

Directions for Use

Fospol Injection 4 gm will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

Fospol Injection 4 gm contains Fosfomycin, a broad-spectrum antibiotic that kills gram-negative and gram-positive bacteria that grow aerobically (in the presence of oxygen) and anaerobically (in the absence of oxygen). Bacterial meningitis (infection of the membranes that protect the brain and spinal cord), complicated urinary tract infections, bacterial infections of bones and joints, heart, lungs, central nervous system, stomach, blood, skin, and tissues beneath the skin are all treated with Fospol Injection 4 gm. Fosfomycin should be used only when other antibiotics have failed or are ineffective. Fospol Injection 4 gm prevents bacterial cell wall formation (a protective covering required for survival). Bacteria are thus killed. Additionally, Fospol Injection 4 gm reduces the attachment of bacteria to the cells lining the urinary bladder.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Fospol Injection 4 gm

  • Taste disturbances
  • Gastrointestinal disturbances
  • Injection site reactions

Drug Warnings

If you are allergic to Fosfomycin or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking Fospol Injection 4 gm. Fospol Injection 4 gm may be used with caution in children if prescribed by a doctor; the dose depends on the child’s age and weight. If you had diarrhoea previously after receiving or taking antibiotics, inform your doctor before taking Fospol Injection 4 gm. If you have kidney problems or are undergoing dialysis, inform your doctor, as the dose may be reduced. 

Drug-Drug Interactions

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FosfomycinBCG vaccine
Severe
FosfomycinCholera vaccines
Severe

Drug-Drug Interactions

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FosfomycinBCG vaccine
Severe
How does the drug interact with Fospol Injection 4 gm:
When BCG vaccine is used with Fospol Injection 4 gm, its effectiveness may be reduced.

How to manage the interaction:
Taking Fospol Injection 4 gm with the BCG vaccine can lead to an interaction, please consult a doctor before taking it.
FosfomycinCholera vaccines
Severe
How does the drug interact with Fospol Injection 4 gm:
Co-administration of the Cholera vaccine with Fospol Injection 4 gm may reduce the activity of the Cholera vaccine.

How to manage the interaction:
If you are currently being treated with Fospol Injection 4 gm or have been treated within the last 14 days, inform your doctor before receiving cholera vaccine, live. Avoid receiving cholera vaccine, live until at least 14 days after you complete your antibiotic therapy to ensure adequate vaccine response.
FosfomycinBalsalazide
Severe
How does the drug interact with Fospol Injection 4 gm:
Fospol Injection 4 gm may reduce the effect of balsalazide when taken orally.

How to manage the interaction:
If you are supposed to take Fospol Injection 4 gm and Balsalazide together, your doctor may adjust the dose or monitor you more frequently to use both medications safely.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Fospol Injection 4 gm in order to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help restore the intestine's good bacteria. 
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as whole-grain bread and brown rice should be included in your diet. 
  • Maintain a low-sodium diet as Fospol Injection 4 gm in injection form may increase sodium levels in the blood.
  • Make sure you drink plenty of water or other fluids daily while you are taking Fospol Injection 4 gm.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Fospol Injection 4 gm Substitute

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Author Details

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Drug-Diseases Interactions

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FOSFOMYCIN-4GMVascular disorders of intestine
Severe
FOSFOMYCIN-4GMCare involving dialysis
Moderate

Drug-Diseases Interactions

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FOSFOMYCIN-4GMVascular disorders of intestine
Severe
How does the disease interact with Fospol Injection 4 gm:
Nearly all antibacterial medications have been associated with Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis, which can range in severity from mild diarrhoea to deadly colitis. Lincomycin and clindamycin are typically to blame. Antibacterial treatment disrupts the colon's normal flora, promoting the growth of C difficile, whose toxins A and B contribute to the emergence of CDAD. When C difficile strains produce hypertoxins, morbidity and death rise; severe infections may not respond to antibiotic therapy and may necessitate colectomy. All individuals who get diarrhoea after taking an antibiotic must be evaluated for CDAD. Careful medical history is required because CDAD has been known to happen more than two months following antibiotic use. Broad-spectrum antibiotics and other medications with potent antibacterial properties should be used in therapy.

How to manage the interaction:
Fospol Injection 4 gm should be used with caution in patients with a history of gastrointestinal disease, particularly colitis (inflammation of the large intestine), pseudomembranous colitis (generally characterized by severe, persistent diarrhoea and severe abdominal cramps, and sometimes associated with the passage of blood and mucus).
FOSFOMYCIN-4GMCare involving dialysis
Moderate
How does the disease interact with Fospol Injection 4 gm:
Hemodialysis removes Fospol Injection 4 gm, therefore it needs to be given after treatments.

How to manage the interaction:
As Fospol Injection 4 gm is removed by hemodialysis, it should be administered after dialysis sessions.
FOSFOMYCIN-4GMUnspecified kidney failure
Mild
How does the disease interact with Fospol Injection 4 gm:
Fospol Injection 4 gm is excreted intact in the faeces (18%) and by the kidneys (38%) of healthy adults. In patients with impaired renal function, the excretion of Fospol Injection 4 gm is greatly reduced, and the half-life is prolonged. In patients with renal insufficiency, side symptoms (such as diarrhoea, headache, nausea, and vaginitis) may last longer.

How to manage the interaction:
Fospol Injection 4 gm should be used with caution in patients with kidney failure. However, if the side effects, such as headache, diarrhoea, nausea, and vaginitis (inflammation or infection of the vagina) worsen, please consult your doctor.

FAQs

Fospol Injection 4 gm contains Fosfomycin, which inhibits the formation of the bacterial cell wall (a protective covering) necessary for survival. Thereby killing bacteria. Also, Fospol Injection 4 gm decreases the attachment of bacteria to cells lining the urinary bladder.

Fospol Injection 4 gm may cause taste disturbances as a temporary side effect. However, if the condition persists or worsens, please inform your doctor.

If you are undergoing dialysis or have kidney problems, inform your doctor before receiving Fospol Injection 4 gm so that the dose may be adjusted.

Fospol Injection 4 gm may cause diarrhoea as a rare side effect. However, if the condition persists or worsens with fever or severe stomach pain, please consult a doctor immediately, as these might be signs of large intestine infection.

You are not recommended to take blood thinner while receiving Fospol Injection 4 gm as co-administration of these two medicines may alter the blood thinner's ability to prevent blood from clotting. However, please consult your doctor before taking other medicines while receiving Fospol Injection 4 gm.

Special Advise

  • The levels of electrolytes are regularly monitored while taking Fospol Injection 4 gm as it may cause high sodium or low potassium levels in the blood.

Disease/Condition Glossary

Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiple very quickly. Bacteria come in three basic shapes, namely spherical, rod or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains, and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever and tiredness. 

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