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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Surge Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Framic M Tablet 500mg/250mg

Framic M Tablet 500mg/250mg is a combination medicine used to treat dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding). Besides this, Framic M Tablet 500mg/250mg is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Menstrual cramps, also known as dysmenorrhea, are characterized by cramps and pain during menstruation. Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods.

Framic M Tablet 500mg/250mg is a combination of two drugs: Tranexamic acid (anti-fibrinolytic) and Mefenamic acid (NSAID). Tranexamic acid helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

You are advised to take Framic M Tablet 500mg/250mg for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, diarrhoea, indigestion, heartburn, and headache. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Framic M Tablet 500mg/250mg may cause dizziness, so drive with caution. Framic M Tablet 500mg/250mg should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Framic M Tablet 500mg/250mg as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Framic M Tablet 500mg/250mg

Dysmenorrhea (period pain) and menorrhagia (heavy menstrual bleeding).

Directions for Use

Take Framic M Tablet 500mg/250mg with food to prevent stomach upset. Swallow Framic M Tablet 500mg/250mg as a whole with a glass of water, do not chew, or break it.

Medicinal Benefits

Framic M Tablet 500mg/250mg is a combination of two drugs, namely: Tranexamic acid and Mefenamic acid. Framic M Tablet 500mg/250mg is used to treat abdominal pain, dysmenorrhea (period pain), and menorrhagia (heavy menstrual bleeding). Additionally, Framic M Tablet 500mg/250mg is also used to treat severe blood loss, swelling in various body parts, fever, inflammation, and migraine headache. Tranexamic acid is an anti-fibrinolytic agent that helps the body's natural blood clot process by preventing fibrin's breakdown, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid is an NSAID that works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. By blocking the COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Framic M Tablet 500mg/250mg helps treat heavy bleeding and pains/cramps during periods.

Storage

Keep Framic M Tablet 500mg/250mg out of reach and sight of children.

Drug Warnings

Do not take Framic M Tablet 500mg/250mg if you are allergic to any of its contents or if you have severe heart failure. Inform your doctor if you have/had deep vein thrombosis, pulmonary embolism (block a blood vessel in the lungs), coagulopathy (formation of blood clots), epilepsy, irregular periods, heart, kidney, or liver problems. Consult your doctor if you are pregnant or breastfeeding. Framic M Tablet 500mg/250mg may cause dizziness and drowsiness, so drive only if you are alert. Framic M Tablet 500mg/250mg should not be given to children as safety and effectiveness have not been established. Avoid consuming alcohol along with Framic M Tablet 500mg/250mg as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Do not take any other NSAIDs for pain relief along with Framic M Tablet 500mg/250mg unless prescribed.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Framic M Tablet 500mg/250mg:
Taking drospirenone with Framic M Tablet 500mg/250mg may increase the risk of blood clot formation.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Drospirenone is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
How does the drug interact with Framic M Tablet 500mg/250mg:
Taking Medroxyprogesterone acetate with Framic M Tablet 500mg/250mg may increase the risk of blood clots.

How to manage the interaction:
Taking Medroxyprogesterone with Framic M Tablet 500mg/250mg is not recommended but can be taken if prescribed by a doctor. Consult your doctor immediately if you experience symptoms such as chest pain, shortness of breath, coughing up blood, blood in the urine, sudden loss of vision, and pain, redness, or swelling in your arm or leg. Do not stop using any medications without talking to your doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Taking Levonorgestrel with Framic M Tablet 500mg/250mg may increase the risk of blood clot formation which can lead to serious conditions such as heart problems and kidney failure.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Levonorgestrel may leads to an interaction but can be taken if prescribed by the doctor. However, if you experience chest pain; shortness of breath; coughing up blood; blood in the urine; sudden loss of vision; and pain, redness, or swelling in your arm or leg, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Taking Ethinylestradiol with Framic M Tablet 500mg/250mg may increase the risk of blood clot formation.

How to manage the interaction:
Taking Ethinylestradiol with Framic M Tablet 500mg/250mg is not recommended, as it can lead to an interaction, but can be taken if a doctor has prescribed it. However, if you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult doctor immediately. Do not stop using any medications without talking to a doctor.
Tranexamic acidEtonogestrel
Critical
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of Framic M Tablet 500mg/250mg may cause blood clotting when taken with Etonogestrel.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Etonogestrel is not recommended, as it can lead to an interaction but can be taken if prescribed by the doctor. However, If you suffer from chest discomfort, shortness of breath, blood in the urine, blood in the cough, sudden loss of vision, and pain, redness, or swelling in your arm or leg, consult your doctor immediately.
How does the drug interact with Framic M Tablet 500mg/250mg:
Coadministration of Framic M Tablet 500mg/250mg with Ketorolac can increase the risk or severity of gastric bleeding and ulcers.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Ketorolac together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of Framic M Tablet 500mg/250mg with Meloxicam together can increase the risk or severity of bleeding.

How to manage the interaction:
Taking Framic M Tablet 500mg/250mg with Meloxicam together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unusual bleeding or bruising, other signs of bleeding, dizziness, lightheadedness, red or black tarry stools, coughing up or vomiting blood, severe headache, and weakness, you should contact a doctor immediately. Do not stop using any medications without talking a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of tretinoin with Framic M Tablet 500mg/250mg may increase the risk of blood clots.

How to manage the interaction:
Taking tretinoin with Framic M Tablet 500mg/250mg is not recommended due to its increased effects, however, it can be taken only if your doctor has advised it. If you experience symptoms such as chest pain, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of tamoxifen with Framic M Tablet 500mg/250mg can increase the risk of blood clots.

How to manage the interaction:
Although taking tamoxifen and Framic M Tablet 500mg/250mg together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
Tranexamic acidOspemifene
Severe
How does the drug interact with Framic M Tablet 500mg/250mg:
Co-administration of ospemifene with Framic M Tablet 500mg/250mg can increase the risk of blood cots.

How to manage the interaction:
Taking ospemifene with Framic M Tablet 500mg/250mg can lead to an interaction, however, it can be taken only if a doctor has advised it. If you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, and numbness or weakness on one side of the body contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a healthy diet. Include vegetables, fruits, and whole grains in your meals.
  • Stay hydrated; drink plenty of water.
  • Cut down on sugars, salts, spicy food, coffee, and alcohol.
  • A heating pad can help ease the pain by placing it on the belly or lower back.
  • Exercise can help ease the pain of menstrual cramps.
  • Avoid stress by performing meditation or yoga.
  • Massage your lower back or abdomen to relieve the pain.
  • Take proper rest.

Side Effects of Framic M Tablet 500mg/250mg

  • Nausea
  • Vomiting
  • Diarrhoea
  • Indigestion
  • Heartburn
  • Headache
  • Musculoskeletal pain
  • Stomach pain

Habit Forming

No

Therapeutic Class

ANTIFIBRINOLYTIC AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Framic M Tablet 500mg/250mg contains Tranexamic acid and Mefenamic acid. Tranexamic acid helps the body's natural blood clot process by preventing the breakdown of fibrin, this stops fibrinolysis, a process that stops blood clot formation. Mefenamic acid works by blocking the effect of chemical messengers that cause pain.

Diarrhoea might be a side-effect of Framic M Tablet 500mg/250mg. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in stools.

Framic M Tablet 500mg/250mg should not be taken for longer durations unless prescribed by the doctor. Framic M Tablet 500mg/250mg is usually prescribed for a few days at the time of heavy bleeding and cramps.

Framic M Tablet 500mg/250mg is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take Framic M Tablet 500mg/250mg only as prescribed and do not overdose.

Consult your doctor before taking contraceptive pills along with Framic M Tablet 500mg/250mg. When taken together, there is an increased risk of deep vein thrombosis (blood clot in the deep vein, usually legs).

Framic M Tablet 500mg/250mg contains mefenamic acid, an NSAID which might increase the risk of cardiovascular thrombotic events, myocardial infarction, and stroke. Therefore, avoid taking Framic M Tablet 500mg/250mg if you have heart-related problems unless prescribed by the doctor.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • CELECOXIB
  • DULOXETINE
  • FLUOXETINE
  • SERTRALINE

Disease/Condition Glossary

Menorrhagia: Menorrhagia is a condition with abnormally heavy or prolonged bleeding during menstruation/periods. The exact cause of menorrhagia is unknown, but it could be due to hormonal imbalance, dysfunction of the ovaries, uterine fibroids, polyps, inherited bleeding disorders, intrauterine devices, or medications. Symptoms include socking through one/more sanitary pads/tampons for every hour, needing to use double sanitary protection to control the flow, needing to wake up during the night to change the pad, bleeding for more than a week, passing blood clots, unable to do daily activities due to heavy flow, tiredness, and fatigue.

Dysmenorrhea: Menstrual cramps, also known as dysmenorrhea, is characterised by cramps and pain during menstruation due to heavy flow. Pain, cramps, and discomfort during periods are normal. However, excessive pain during periods is not normal and requires medication. Symptoms of dysmenorrhea include intense throbbing pain in the lower abdomen, dull, continuous aches, pain in the lower back and thighs, nausea, headache, and dizziness. The pain usually starts 1-3 days prior to the period, peaks one day before the period starts, and subsides 2-3days after the onset of the period.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Framic M Tablet 500mg/250mg as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

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Pregnancy

Caution

Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Framic M Tablet 500mg/250mg if you are breastfeeding, your doctor will decide if Framic M Tablet 500mg/250mg can be taken by breastfeeding mothers or not.

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Driving

Caution

Framic M Tablet 500mg/250mg may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with renal disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Framic M Tablet 500mg/250mg should not be given to children as the safety and effectiveness were not established.

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