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Prescription drugWhats That
Composition :
GLIMEPIRIDE-2MG
Manufacturer/Marketer :
RB Pharmaceuticals
Consume Type :
ORAL
Return Policy :
Not Returnable
Expires on or after :
Drug-Drug Interactions
Severe
GlimepiridePromazine
Severe
Drug-Drug Interactions
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Severe
How does the drug interact with Gliben-2 Tablet:
Co-administration of Ofloxacin and Gliben-2 Tablet can sometimes have an effect on blood glucose levels.
How to manage the interaction:
Although combining Ofloxacin and Gliben-2 Tablet can lead to an interaction, they can be taken on a doctor's advice. If you experience any symptoms of hypoglycemia (headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweat, palpitation, and rapid heartbeat) or hyperglycemia (increased thirst, hunger, and urination), consult a doctor. Keep an eye on your blood glucose level. Do not discontinue any medications without consulting a doctor.
Co-administration of Ofloxacin and Gliben-2 Tablet can sometimes have an effect on blood glucose levels.
How to manage the interaction:
Although combining Ofloxacin and Gliben-2 Tablet can lead to an interaction, they can be taken on a doctor's advice. If you experience any symptoms of hypoglycemia (headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweat, palpitation, and rapid heartbeat) or hyperglycemia (increased thirst, hunger, and urination), consult a doctor. Keep an eye on your blood glucose level. Do not discontinue any medications without consulting a doctor.
GlimepiridePromazine
Severe
How does the drug interact with Gliben-2 Tablet:
When Gliben-2 Tablet is taken with Promazine may interfere with blood glucose control and reduce the effectiveness of Gliben-2 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Gliben-2 Tablet and Promazine, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
When Gliben-2 Tablet is taken with Promazine may interfere with blood glucose control and reduce the effectiveness of Gliben-2 Tablet.
How to manage the interaction:
There may be a possibility of interaction between Gliben-2 Tablet and Promazine, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much urine you're producing. If you notice any of these signs - very high or very low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Gliben-2 Tablet:
Taking Gliben-2 Tablet with Paroxetine may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with paroxetine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Gliben-2 Tablet with Paroxetine may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with paroxetine if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar like headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Gliben-2 Tablet:
Co-administration of Leflunomide may increase the blood levels and effects of Gliben-2 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Leflunomide may increase the blood levels and effects of Gliben-2 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Gliben-2 Tablet:
Taking Gliben-2 Tablet with Vilazodone may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Vilazodone if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Gliben-2 Tablet with Vilazodone may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Vilazodone if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Gliben-2 Tablet:
Co-administration of Sparfloxacin with Gliben-2 Tablet can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Sparfloxacin with Gliben-2 Tablet can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideTrovafloxacin
Severe
How does the drug interact with Gliben-2 Tablet:
When Gliben-2 Tablet is taken with Trovafloxacin, it can affect blood glucose levels either hypoglycemia or hyperglycemia.
How to manage the interaction:
Taking Gliben-2 Tablet with Trovafloxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to be aware of symptoms like increased urination and thirst, and to contact your doctor if you experience any concerning symptoms. Your doctor may be able to suggest alternative medications that don't interact with your diabetes treatment. Do not stop using any medications without a doctor's advice.
When Gliben-2 Tablet is taken with Trovafloxacin, it can affect blood glucose levels either hypoglycemia or hyperglycemia.
How to manage the interaction:
Taking Gliben-2 Tablet with Trovafloxacin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to be aware of symptoms like increased urination and thirst, and to contact your doctor if you experience any concerning symptoms. Your doctor may be able to suggest alternative medications that don't interact with your diabetes treatment. Do not stop using any medications without a doctor's advice.
How does the drug interact with Gliben-2 Tablet:
When Gliben-2 Tablet is taken with Nalidixic acid, can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
There may be a possibility of interaction between Gliben-2 Tablet and Nalidixic acid, but it can be taken if prescribed by a doctor. It's important to monitor your blood sugar levels closely. If you experience symptoms like kidney problems, low or high blood sugar, or other concerning symptoms, contact a doctor right away. They may be able to suggest alternative medications that won't interact with a diabetes treatment. Do not discontinue any medications without consulting a doctor.
When Gliben-2 Tablet is taken with Nalidixic acid, can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
There may be a possibility of interaction between Gliben-2 Tablet and Nalidixic acid, but it can be taken if prescribed by a doctor. It's important to monitor your blood sugar levels closely. If you experience symptoms like kidney problems, low or high blood sugar, or other concerning symptoms, contact a doctor right away. They may be able to suggest alternative medications that won't interact with a diabetes treatment. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Gliben-2 Tablet:
Co-administration of Gliben-2 Tablet with Isoniazid may interfere with blood glucose control and reduce the effectiveness of Gliben-2 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Isoniazid if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Gliben-2 Tablet with Isoniazid may interfere with blood glucose control and reduce the effectiveness of Gliben-2 Tablet.
How to manage the interaction:
Although there is a possible interaction, Gliben-2 Tablet can be taken with Isoniazid if prescribed by the doctor. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Severe
How does the drug interact with Gliben-2 Tablet:
Co-administration of Gliben-2 Tablet with Levofloxacin can affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Co-administration of Levofloxacin with Gliben-2 Tablet can result in an interaction, it can be taken if a doctor has advised it. Consult the prescriber if you experience dizziness, drowsiness, headache, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased urination, increased thirst, or increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Gliben-2 Tablet with Levofloxacin can affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Co-administration of Levofloxacin with Gliben-2 Tablet can result in an interaction, it can be taken if a doctor has advised it. Consult the prescriber if you experience dizziness, drowsiness, headache, nervousness, confusion, tremors, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, increased urination, increased thirst, or increased hunger. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
GLIMEPIRIDE-2MGHypertensive heart and renal disease
Severe
GLIMEPIRIDE-2MGUnspecified kidney failure
Severe
Drug-Diseases Interactions
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GLIMEPIRIDE-2MGHypertensive heart and renal disease
Severe
How does the disease interact with Gliben-2 Tablet:
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIMEPIRIDE-2MGUnspecified kidney failure
Severe
How does the disease interact with Gliben-2 Tablet:
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
GLIMEPIRIDE-2MGOther disorders of adrenal gland
Moderate
How does the disease interact with Gliben-2 Tablet:
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
GLIMEPIRIDE-2MGAnaemia due to enzyme disorders
Moderate
How does the disease interact with Gliben-2 Tablet:
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
GLIMEPIRIDE-2MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Gliben-2 Tablet:
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
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