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Written By aquibnaseer ,
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

GLIMEPIRIDE-2MG

Manufacturer/Marketer :

Aretaeus Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About GMP-2 Tablet

GMP-2 Tablet belongs to a class of antidiabetic called 'sulfonylureas' used to lower raised blood sugar levels in Type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus - NIDDM). Type 2 diabetes develops if the body does not produce enough insulin or when your body's insulin does not work as well as it should. Insulin is a substance that helps to lower the level of sugar in your blood, especially after meals.

The GMP-2 Tablet contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

Take GMP-2 Tablet as prescribed by your doctor. Some people may experience an allergic reaction (skin rash, hives & sensitivity to sun rays), liver dysfunction (jaundice, bile duct blockage, and hepatitis), seizures, coma & low glucose levels. Most of these side effects of GMP-2 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

GMP-2 Tablet should not be stopped even if you feel better without consulting your doctor as the sugar level keeps changing. If you stop taking GMP-2 Tablet abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy) and nerve damage (neuropathy). GMP-2 Tablet should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease. Please inform your doctor if you have any heart disease or plan to get pregnant or breastfeed.

Uses of GMP-2 Tablet

Type 2 diabetes

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

GMP-2 Tablet is used in people with type 2 diabetes to minimize elevated blood sugar levels with a balanced diet and exercise in combination. GMP-2 Tablet  can be combined with insulin or other forms of oral antidiabetic medication. GMP-2 Tablet decreases blood sugar levels in a diabetic patient by increasing the production and secretion of insulin from the pancreas beta cells. Thus, it helps in controlling increased blood sugar levels after the meal.

Storage

Keep out of sight and reach of children.
Side effects of GMP-2 Tablet
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Before taking GMP-2 Tablet , inform your doctor if you are healing from injury, had or going to have surgery, have fever infections or other sources of stress, then contact your doctor as it might be appropriate to adjust care temporarily. If you have a serious kidney/liver disease, breastfeeding or pregnant, consult the doctor before using GMP-2 Tablet . Do not take GMP-2 Tablet if you are allergic to sulpha drugs, glimepiride, or any other antidiabetic medicines or have a deficiency of glucose 6-phosphate dehydrogenase (G6PD). A heart disease patient should consult a doctor before taking the GMP-2 Tablet as it may worsen the heart disease's current conditions. Do not take GMP-2 Tablet with oral contraceptives as it may increase blood sugar levels. On the other hand, taking GMP-2 Tablet with pain killers like aspirin or ibuprofen can lower your blood sugar.

Drug-Drug Interactions

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MetforminMetrizamide
Critical
MetforminIopanoic acid
Critical

Drug-Drug Interactions

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MetforminMetrizamide
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of GMP-2 Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking GMP-2 Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIopanoic acid
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Iopanoic acid with GMP-2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking GMP-2 Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of GMP-2 Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking GMP-2 Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoglicic acid
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Ioglicic acid with GMP-2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking GMP-2 Tablet with Ioglicic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIoversol
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Ioversol with GMP-2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking GMP-2 Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of GMP-2 Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking GMP-2 Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopromide
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Iopromide with GMP-2 Tablet can increase the risk of lactic acidosis.

How to manage the interaction:
Taking Iopromide with GMP-2 Tablet is not recommended, please consult a doctor before taking it. Do not discontinue the medication without consulting a doctor.
MetforminIoglycamic acid
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Ioglycamic acid with GMP-2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking GMP-2 Tablet with Ioglycamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Iomeprol with GMP-2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking GMP-2 Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIopentol
Critical
How does the drug interact with GMP-2 Tablet:
Co-administration of Iopentol with GMP-2 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking GMP-2 Tablet with Iopentol is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day. Invest at least 150 minutes of your week in exercise.
  • Maintain healthy body weight as obesity is also related to the onset of diabetes.
  • Maintain a low fat and a low sugar diet. Replace carbohydrates containing foods with whole grains, fruits and vegetables as carbohydrates turn to sugars leading to high blood sugar.
  • Avoid consumption of alcohol and quit smoking.

Side Effects of GMP-2 Tablet

  • Allergic reactions
  • Headache
  • Nausea
  • Blood pressure drop
  • Shock
  • Abnormal liver function
  • Including skin and eye yellowing (jaundice)
  • Bile flow issues (cholestasis)
  • Liver inflammation (hepatitis) or failure of the liver

Habit Forming

No

Therapeutic Class

ANTIDIABETICS AND ANTIHYPERGLYCEMICS

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

The GMP-2 Tablet contains Glimepiride which acts on insulin-secreting cells called beta cells inside the pancreas and activates calcium channels on cells which lets insulin pass out of the cell. This insulin then makes each cell in the body take up glucose and utilize it, thus lowering raised blood glucose. Therefore, it prevents symptoms of type 2 diabetes.

A patient is advised to take the missed dose as soon as possible or skip to the next dose if it's been too late. A patient should never attempt to take a double dose to compensate for the missed dose as it may prove harmful.

GMP-2 Tablet is not recommended with warfarin as these two drugs are contraindicated with each other and hence may result in any harmful symptom when taken together in heart patients.

Avoid intake of GMP-2 Tablet and consult a doctor if you have an allergy to sulfa drugs, diabetic ketoacidosis, heart disease, liver or kidney disease, an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD).

Your blood sugar might get decreased, so regular blood glucose monitoring is required. Signs and symptoms of low blood sugar level are feeling very hungry, dizziness, irritability, confusion, anxiety or shakiness. Try to eat or drink a fast-acting sugar source (like fruit juice, hard candy, crackers, raisins or non-diet soda).

No, GMP-2 Tablet is only prescribed to treat type 2 diabetes and not type 1 diabetes. If you are type 1 diabetic patient consult with a doctor so that insulin forms can be prescribed for the same.

The patient is advised to talk to a doctor before taking contraceptive pills if he/she is already taking GMP-2 Tablet , then the doctor may change the dose of GMP-2 Tablet . This is because oral contraceptive pills change body responds to the sugar.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ROSUVASTATIN
  • DULOXETINE
  • DAPAGLIFLOZIN
  • GLYBURIDE
  • INSULIN
  • CANAGLIFLOZIN
  • SITAGLIPTIN
  • EMPAGLIFLOZIN
  • FUROSEMIDE
  • ATORVASTATIN
  • PREGABALIN
  • METFORMIN
  • NAPROXEN
  • CLOPIDOGREL
  • IBUPROFEN
  • WARFARIN

Disease/Condition Glossary

Type 2 diabetes: It is a chronic (long-lasting) condition that keeps the body from properly utilizing insulin. Hence, people affected with type 2 diabetes either do not produce enough insulin, or there is resistance to the action of insulin. Middle-aged or older are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes. Symptoms of type 2 diabetes include increased thirst, frequent urination at night, slow wound healing, increased hunger, fatigue, and blurred vision. In some cases, there may be weight gain while in rare cases weight loss may be observed. The complication of type 2 diabetes also includes nerve problems, kidney problems, the damaged retina of eyes or blindness, loss of limbs, sexual dysfunction, and an increased chance of heart attack or stroke.

Have a query?

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Alcohol

Caution

Not recommended to take GMP-2 Tablet with alcohol. Alcohol intake may increase or decrease the blood sugar lowering action of GMP-2 Tablet in an unpredictable way resulting in a harmful event.

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Pregnancy

Caution

GMP-2 Tablet is a pregnancy Category C medicine which means that there are no well-controlled studies that have been done in pregnant women. However, if you are taking GMP-2 Tablet during pregnancy, stop taking it at least 2 weeks before your due date or as prescribed by your doctor.

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Breast Feeding

Caution

Not recommended to be taken by breastfeeding mothers. GMP-2 Tablet may pass into breast milk and may cause the risk of low blood sugar in the infant. Consult your doctor for further advice.

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Driving

Caution

Not recommended in patients with fluctuating glucose levels. GMP-2 Tablet can reduce the ability to concentrate or react, if your blood sugar is lowered (hypoglycemia) or raised (hyperglycemia) or if you develop visual problems as a result of such conditions. Thus not recommended as the patient can endanger himself or others (e.g. when driving a car or using machines).

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Liver

Caution

Not recommended in patients with liver dysfunction. A patient should consult a doctor before taking GMP-2 Tablet as it may cause liver damage.

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Kidney

Caution

Not recommended in patients with kidney dysfunction. A patient should consult a doctor before taking GMP-2 Tablet as it may cause kidney damage.

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Children

Unsafe

GMP-2 Tablet is not approved for use by a person less than 18 years old.

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