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Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Ingram Biosciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Gramoz-IT Capsule

Gramoz-IT Capsule is a combination medicine of proton pump inhibitor and prokinetic agent used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.

Gramoz-IT Capsule is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain that is responsible for controlling vomiting.  It increases gastric emp undying improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Gramoz-IT Capsule helps prevent acid reflux, thereby relieving acidity.

Take Gramoz-IT Capsule 30-60 minutes before food. Do not chew or break the tablet; swallow it as a whole with a glass of water. You are advised to take Gramoz-IT Capsule for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Inform your doctor before taking Gramoz-IT Capsule if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, Gramoz-IT Capsule may cause osteoporosis and hypomagnesemia (low levels of magnesium). Do not take Gramoz-IT Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Gramoz-IT Capsule causes drowsiness, so drive only if you are alert. Gramoz-IT Capsule should not be given to children as safety has not been established. Avoid consuming alcohol with Gramoz-IT Capsule as it can lead to increased drowsiness and increased acid production. 

Uses of Gramoz-IT Capsule

Hyperacidity, Gastro-oesophageal reflux disease, Peptic ulcer

Directions for Use

Take this medicine 30-60 minutes before food. Do not chew or crush it; swallow it as a whole with a glass of water. Depending on your medical condition, your doctor will decide how long you need to take this medicine.

Medicinal Benefits

Gramoz-IT Capsule is a combination of two drugs:  Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting.  It increases gastric emptying and improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, Gramoz-IT Capsule helps prevent acid reflux, thereby relieving acidity.
 

Storage

Keep Gramoz-IT Capsule out of reach and sight of children.
Side effects of Gramoz-IT Capsule
  • Wash your hands regularly with soap and water or use a hand sanitizer to prevent the spread of infections.
  • Wear masks, gloves and other protective clothing.
  • Cover sneezes and coughs with a medical mask or tissue or your elbow.
  • Take vaccinations to enhance your immunity to specific diseases.
  • Clean your utensils, linen and surfaces regularly.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Managing Medication-Triggered Rhinitis (Stuffy Nose): A Step-by-Step Guide
  • Consult your doctor if you experience nasal congestion, runny nose, or sinus pressure after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your rhinitis symptoms.
  • If advised by your doctor, use nasal decongestants or saline nasal sprays to help relieve nasal congestion.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of water and other fluids to help thin out mucus and soothe your nasal passages.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Do not take Gramoz-IT Capsule if you are allergic to any of its contents. Inform your doctor before taking Gramoz-IT Capsule if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. Gramoz-IT Capsule may cause osteoporosis on long-term treatment. Gramoz-IT Capsule may also cause hypomagnesemia (low magnesium). Do not take Gramoz-IT Capsule if you are pregnant or breastfeeding unless prescribed by the doctor. Gramoz-IT Capsule causes dizziness, so drive only if you are alert. Gramoz-IT Capsule should not be given to children as safety has not been established. Avoid consuming alcohol along with Gramoz-IT Capsule as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about all the medicines and your health condition to rule out any side effects.  Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, Gramoz-IT Capsule may cause osteoporosis and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical

Drug-Drug Interactions

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RabeprazoleRilpivirine
Critical
How does the drug interact with Gramoz-IT Capsule:
Co-administration of Gramoz-IT Capsule can make Rilpivirine less effective by reducing its absorption in the body.

How to manage the interaction:
Taking Gramoz-IT Capsule with Rilpivirine is not recommended, but can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Gramoz-IT Capsule:
When used in combination with erlotinib, Gramoz-IT Capsule may prevent the absorption of erlotinib into the circulation, which might make erlotinib less effective in treating cancer.

How to manage the interaction:
Taking Gramoz-IT Capsule with Erlotinib is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
How does the drug interact with Gramoz-IT Capsule:
Taking Gramoz-IT Capsule together with Pazopanib can result in a decreased effectiveness of Pazopanib in treating the disease.

How to manage the interaction:
Although taking Gramoz-IT Capsule and Pazopanib together can result in an interaction, but can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
How does the drug interact with Gramoz-IT Capsule:
Co-administration of Methotrexate with Gramoz-IT Capsule can increase the blood levels and side effects of Methotrexate.

How to manage the interaction:
Although there is a possible interaction between Gramoz-IT Capsule and Methotrexate, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
How does the drug interact with Gramoz-IT Capsule:
Taking Gramoz-IT Capsule together with Dasatinib results in decreased levels of Dasatinib and its effectiveness.

How to manage the interaction:
Although taking Gramoz-IT Capsule and Dasatinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gramoz-IT Capsule:
When Phenytoin and Gramoz-IT Capsule are taken in combination, Phenytoin will reduce the concentration or impact of Gramoz-IT Capsule.

How to manage the interaction:
Although taking Phenytoin and Gramoz-IT Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gramoz-IT Capsule:
Taking Gramoz-IT Capsule together with Acalabrutinib results in a decreased effectiveness of Acalabrutinib.

How to manage the interaction:
Although taking Gramoz-IT Capsule and Acalabrutinib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
RabeprazoleIdelalisib
Severe
How does the drug interact with Gramoz-IT Capsule:
When Gramoz-IT Capsule and Idelalisib are taken in combination, Idelalisib may increase the level or impact of Gramoz-IT Capsule.

How to manage the interaction:
Although taking Gramoz-IT Capsule and Idelalisib together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gramoz-IT Capsule:
Taking Gramoz-IT Capsule together with Gefitinib results in decreased levels of gefitinib in your blood. This can result in a decreased effectiveness of gefitinib in treating the disease.

How to manage the interaction:
Although taking Gramoz-IT Capsule and Gefitinib together can possibly result in an interaction, it can be taken if your doctor has prescribed it. To lessen the effects of the interaction, it is advised that you take gefitinib 12 hours before or 12 hours after Gramoz-IT Capsule. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Gramoz-IT Capsule:
Taking Clopidogrel with Gramoz-IT Capsule can reduce the effectiveness of Clopidogrel.

How to manage the interaction:
Taking Clopidogrel and Gramoz-IT Capsule together possibly has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating.
  • Avoid tight-fitting clothes.
  • Maintain a healthy weight by regular exercising.
  • Practice relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
  • Avoid sitting continuously, as it may trigger acidity. Take a break of 5minutes break every hour by doing brisk walking or stretching.

Side Effects of Gramoz-IT Capsule

  • Nausea
  • Dizziness
  • Diarrhoea 
  • Headache
  • Stomach pain

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Gramoz-IT Capsule is a combination of two drugs:  Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI), that works by blocking the action of an enzyme called gastric proton pump, which is responsible for the production of acid. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain responsible for controlling vomiting.  It increases gastric emptying, and improves gastric sensitivity and tension by increasing the movement of the stomach, and intestines in the upper digestive tract. It also has anti-emetic action. Together, Gramoz-IT Capsule helps prevent acid reflux and provide relief from acidity.

Talk to your doctor if you do not feel better even after taking Gramoz-IT Capsule for 14 days. Do not take Gramoz-IT Capsule for longer durations unless prescribed by the doctor.

Diarrhoea might be a side-effect of Gramoz-IT Capsule . Drink enough fluids and eat fibre-rich food if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience excess diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Avoid or limit the consumption of alcohol while taking Gramoz-IT Capsule as it may lead to increased dizziness. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

Avoid lying down immediately after meals to prevent acid reflux. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This helps in preventing acid reflux.

Gramoz-IT Capsule contains lactose monohydrate, so a person who is intolerant to sugar should tell their doctor before taking this medicine.

Consult your doctor before taking Gramoz-IT Capsule if you are pregnant or planning for pregnancy. Your doctor will prescribe Gramoz-IT Capsule only if the benefits outweigh the risks.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • NAPROXEN
  • DULOXETINE
  • LEVOTHYROXINE SODIUM
  • ATORVASTATIN
  • CLOPIDOGREL
  • CYANOCOBALAMIN

Special Advise

  • Inform your doctor before taking Gramoz-IT Capsule if you are due to have Chromogranin A test.
  • Regular tests of magnesium and calcium are suggested if you are regularly taking prescribed Gramoz-IT Capsule . 

Disease/Condition Glossary

Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like GERD, acidity, and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste, and difficulty swallowing. Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Gramoz-IT Capsule . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

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Pregnancy

Caution

Consult your doctor before taking Gramoz-IT Capsule if you are pregnant; your doctor will prescribe only if the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor before taking Gramoz-IT Capsule ; your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Gramoz-IT Capsule causes dizziness. Do not drive or operate machinery unless you are alert.

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Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Gramoz-IT Capsule if you have a liver impairment or any concerns.

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Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Gramoz-IT Capsule if you have kidney impairment or any concerns.

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Children

Unsafe

Gramoz-IT Capsule should not be given to children as safety and effectiveness were not established.

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