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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma

About Graniforce Syrup 30 ml

Graniforce Syrup 30 ml belongs to the class of ‘anti-emetic’ drugs, primarily used to treat nausea and vomiting caused by medical treatments, such as chemotherapy or radiation treatment for cancer, etc. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.

Graniforce Syrup 30 ml contains an anti-emetic (eases vomiting symptoms) medicine, 'Granisetron' that belongs to the class of serotonin receptor antagonists or serotonin blockers. It works by blocking the activity of serotonin (chemical messenger) in the brain that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.

Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of Graniforce Syrup 30 ml include diarrhoea, constipation, stomach pain, weakness, headache, fever, dizziness, drowsiness, trouble sleeping , and anxiety. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

If you use other prescription or non-prescription medicines, inform your doctor before using Graniforce Syrup 30 ml. Let your doctor know if you have any liver, kidney, or heart diseases, stomach/intestinal problems, allergic reactions , and low levels of potassium and magnesium in the blood before starting Graniforce Syrup 30 ml. Graniforce Syrup 30 ml may make you dizzy or drowsy, hence avoid driving if you are not mentally alert. Consult your doctor before taking Graniforce Syrup 30 ml if you are pregnant, planning for pregnancy, or breastfeeding. Avoid consuming alcohol along with Graniforce Syrup 30 ml as it could lead to increased drowsiness. 

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

GRANISETRON-1MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Graniforce Syrup 30 ml

Nausea and vomiting.

Medicinal Benefits

Graniforce Syrup 30 ml contains an anti-emetic drug, 'Granisetron' that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery, etc. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. Graniforce Syrup 30 ml works by blocking the activity of serotonin in the brain and preventing post-operative nausea and vomiting.

Side Effects of Graniforce Syrup 30 ml

  • Diarrhoea
  • Constipation
  • Stomach pain
  • Weakness
  • Headache
  • Fever
  • Dizziness
  • Drowsiness
  • Trouble sleeping
  • Anxiety

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water, do not chew, crush or break it.Syrup/Liquid: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Graniforce Syrup 30 ml may cause serotonin syndrome/toxicity when used with other drugs like ecstasy (MDMA) and antidepressants. Hence it is suggested to seek medical advice if you are using any prescription or non-prescription medicines. Inform your doctor if you have a history of stomach/intestinal problems like stomach ache, wind, feeling or being sick, and difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), and liver or kidney diseases before starting Graniforce Syrup 30 ml. Please consult your doctor if you are pregnant or breastfeeding if the doctor has advised you Graniforce Syrup 30 ml. Graniforce Syrup 30 ml may make you feel dizzy, so drive only if you are alert. Avoid consuming alcohol as it could lead to increased dizziness. Graniforce Syrup 30 ml is not recommended in children below two years of age.

Therapeutic Class

ANTIEMETICS

Drug-Drug Interactions

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GranisetronZiprasidone
Critical
GranisetronPimozide
Critical

Drug-Drug Interactions

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GranisetronZiprasidone
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with Ziprasidone can increase the risk of abnormal heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Ziprasidone is not recommended, as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronPimozide
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with Pimozide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Pimozide is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronSparfloxacin
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with Sparfloxacin can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Sparfloxacin is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GranisetronCisapride
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with Cisapride can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Cisapride is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronThioridazine
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with Thioridazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Thioridazine is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronMesoridazine
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with mesoridazine can increase the risk of an irregular heart rhythm. I

How to manage the interaction:
Taking Mesoridazine with Graniforce Syrup 30 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronSaquinavir
Critical
How does the drug interact with Graniforce Syrup 30 ml:
When Graniforce Syrup 30 ml is taken with Saquinavir, can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Saquinavir is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronDronedarone
Critical
How does the drug interact with Graniforce Syrup 30 ml:
Taking Graniforce Syrup 30 ml with Dronedarone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Graniforce Syrup 30 ml with Dronedarone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations while taking any of these drugs, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
GranisetronAmitriptyline
Severe
How does the drug interact with Graniforce Syrup 30 ml:
Coadministration of Amitriptyline and Graniforce Syrup 30 ml may increase the risk of irregular heartbeat and can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although combining Amitriptyline with Graniforce Syrup 30 ml can lead to an interaction, they can be taken if prescribed by a doctor. If you have sudden dizziness, lightheadedness, fainting, confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles, or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea, or fast or rapid heartbeats during therapy, get emergency medical help. Inform a doctor if you have recently taken amitriptyline. Do not discontinue any medication without consulting a doctor.
GranisetronAmiodarone
Severe
How does the drug interact with Graniforce Syrup 30 ml:
Coadministration of Graniforce Syrup 30 ml with amiodarone may increase the risk of abnormal cardiac rhythms.

How to manage the interaction:
Although taking Graniforce Syrup 30 ml with amiodarone may cause an interaction, it is safe to do so if a doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LITHIUM
  • DULOXETINE
  • AMIODARONE
  • QUINIDINE
  • RITONAVIR
  • ERYTHROMYCIN

Diet & Lifestyle Advise

  • Avoid chocolates, junk food, cheese, processed food, alcohol and smoking.
  • You can try increasing your mindfulness by doing yoga, meditation, mindfulness-based cognitive therapy and stress reduction techniques.
  • Drink enough water to stay hydrated and limit or avoid alcohol and caffeine.
  • Include a diet rich in whole grains, vegetables and fruits. This is a healthier option than eating a lot of simple carbohydrates found in processed foods.
  • You can include antioxidants in your daily diet like ashwagandha, omega-3 fatty acids, green tea and lemon balm.
  • Try to spend time with your friends and family. Having a strong social network may help you lower your risk of anxiety.

Habit Forming

No

Special Advise

Let your doctor know that you are taking Graniforce Syrup 30 ml if you are undergoing any medical tests.

Author Details

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Disease/Condition Glossary

Nausea is defined as stomach discomfort and the sensation of an urge to vomit. It is a precursor to vomiting. It is not a painful symptom but can cause discomfort in the chest, upper abdomen or back of the throat. Nausea can be triggered by various factors like motion from a car and plane, taking pills on an empty stomach, eating too much or too little and drinking excessive amounts of alcohol.

Vomiting or throwing up is the forcible voluntary or involuntary emptying of the stomach contents through the mouth. Vomiting can also occur without having any underlying diseases in conditions like pregnancy, hangover, overeating and motion sickness. Nausea or vomiting may be triggered by many factors, including food poisoning, gastritis (inflammation of the stomach lining), an ulcer or bulimia (eating disorder).

Graniforce Syrup 30 ml Substitute

Substitutes safety advice
  • Grandem Md Tablet 10's

    by AYUR

    10.35per tablet
  • Graniforce -MD Tablet 10's

    9.23per tablet
  • Grandem-1 Tablet 10's

    by AYUR

    9.45per tablet
  • Graniset 1 Tablet 4's

    24.98per tablet
  • GRANIFORCE INJECTION 1ML

    26.28per tablet
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