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Hepbest Tablet 30's, Pack of 1 TABLET
Hepbest Tablet 30's, Pack of 1 TABLET
Hepbest Tablet 30's, Pack of 1 TABLET
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Veda Maddala , M Pharmacy
Non returnable*
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COD available

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rxMedicinePrescription drug

Whats That

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Composition :

TENOFOVIR ALAFENAMIDE-25MG

Manufacturer/Marketer :

Mylan Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hepbest Tablet

Hepbest Tablet belongs to the group of medicines known as ‘antiviral medicines used to treat chronic hepatitis B virus (HBV) infection in adults with compensated liver disease. Chronic hepatitis B is a long-term viral infection caused by the hepatitis B virus.

Hepbest Tablet contains ‘Tenofovir alafenamide’. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby, it prevents the virus from producing new viruses and clears the infection.

Take Hepbest Tablet as prescribed by your doctor. Therapy should be initiated by a physician experienced in managing chronic hepatitis B. You may sometimes experience headaches, diarrhoea, vomiting, feeling sick (nausea), and rash. Most of these side effects of Hepbest Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

You should not take Hepbest Tablet if you are allergic to Hepbest Tablet or any other contents present in it. Avoid taking Hepbest Tablet if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You are recommended to avoid driving while using Hepbest Tablet as it may cause dizziness, affecting your ability to drive or use machines. Should not use Hepbest Tablet for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Uses of Hepbest Tablet

Chronic hepatitis B

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Hepbest Tablet ‘tenofovir alafenamide’, an antiviral drug used to treat hepatitis B virus (HBV) infection in adults with compensated liver disease. It inhibits HBV replication by incorporating the HBV reverse transcriptase into viral DNA, resulting in DNA chain termination. Thereby it prevents the virus from producing new viruses and cleans up your infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Hepbest Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

You should not take Hepbest Tablet if you are allergic to Hepbest Tablet or any other contents present in it. Avoid taking Hepbest Tablet if you have or had a history of severe kidney or liver impairment. Inform your doctor if you are pregnant, planning to become pregnant, and breastfeeding. Avoid drinking alcohol as it may increase the risk of side effects. You should not drive while using Hepbest Tablet as Hepbest Tablet may cause dizziness, affecting your ability to drive or use machines. Hepbest Tablet is not recommended for children less than 12 years of age. Patients should take necessary precautions to avoid infecting others.

Drug-Drug Interactions

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Tenofovir alafenamideCidofovir
Critical
Tenofovir alafenamideGentamicin
Severe

Drug-Drug Interactions

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Tenofovir alafenamideCidofovir
Critical
How does the drug interact with Hepbest Tablet:
Coadministration of Cidofovir and Hepbest Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Cidofovir and Hepbest Tablet together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Tenofovir alafenamideGentamicin
Severe
How does the drug interact with Hepbest Tablet:
Co-administration of Hepbest Tablet may cause kidney problems and combining it gentamicin may increase that risk.

How to manage the interaction:
Although there is a possible interaction, gentamicin can be taken with Hepbest Tablet if prescribed by the doctor. Consult the doctor if you experience signs and symptoms of kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without consulting a doctor.
Tenofovir alafenamideAdefovir dipivoxil
Severe
How does the drug interact with Hepbest Tablet:
The combined use of Adefovir dipivoxil and Hepbest Tablet can increase the risk of kidney problems.

How to manage the interaction:
Taking Adefovir dipivoxil and Hepbest Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir alafenamideAmikacin
Severe
How does the drug interact with Hepbest Tablet:
Coadministration of Amikacin with Hepbest Tablet can increase the risk of developing kidney problems.

How to manage the interaction:
Although taking amikacin and Hepbest Tablet together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor if you experience vomiting, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, weakness, or palpitation. Do not discontinue any medications without a doctor's advice.
Tenofovir alafenamideLeflunomide
Severe
How does the drug interact with Hepbest Tablet:
Taking leflunomide with Hepbest Tablet can increase the risk of liver problems.

How to manage the interaction:
Taking Leflunomide and Hepbest Tablet together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
Tenofovir alafenamideIbandronic acid
Severe
How does the drug interact with Hepbest Tablet:
Co-administration of Hepbest Tablet with Ibandronic acid can increase the risk of kidney damage.

How to manage the interaction:
Taking Ibandronic acid with Hepbest Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience symptoms such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, pain in the muscles, weakness, tiredness, dizziness, confusion, and irregular heart rhythm, consult a doctor. Do not stop using any medications without consulting a doctor.
Tenofovir alafenamideSirolimus
Severe
How does the drug interact with Hepbest Tablet:
Co-administration of Sirolimus and Hepbest Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Sirolimus and Hepbest Tablet together can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Tenofovir alafenamideIndometacin
Severe
How does the drug interact with Hepbest Tablet:
Co-administration of Indomethacin with Hepbest Tablet may increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Indometacin with Hepbest Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, lack of appetite, increased or decreased urination, weight gain or loss that occurs suddenly, fluid retention, swelling, breathing difficulty, cramping in the muscles, disorientation, confusion, and irregular heartbeat, consult a doctor. Do not stop using any medications without consulting a doctor.
Tenofovir alafenamideVancomycin
Severe
How does the drug interact with Hepbest Tablet:
Coadministration of Vancomycin with Hepbest Tablet can increase the risk or severity of kidney problems.

How to manage the interaction:
Taking Vancomycin with Hepbest Tablet may result in an interaction, they can be taken together if prescribed by a doctor. However, contact a doctor immediately if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medication without consulting a doctor.
Tenofovir alafenamideCelecoxib
Severe
How does the drug interact with Hepbest Tablet:
Taking celecoxib with Hepbest Tablet may increase risk of kidney problems.

How to manage the interaction:
Although taking Celecoxib and Hepbest Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a diet that includes fresh fruits and vegetables.
  • Opt for lean meat such as skinless chicken and fish.
  • Limit processed and high-sugar foods.
  • Avoid acidic foods such as tomatoes, lemons, and oranges.
  • Limit alcohol intake and quit smoking.
  • Exercise regularly as it promotes both physical and mental health.
  • Take the necessary precautions to avoid the spread of infection to other people.

Habit Forming

No

Therapeutic Class

ANTIVIRALS

Hepbest Tablet Substitute

Substitutes safety advice

Product Substitutes

Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Veda MaddalaDoctor badge

Reviewed By

Veda Maddala

M Pharmacy

Last Updated

Jul 8, 2025 | 9:40 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Hepbest Tablet contains ‘tenofovir alfenamide’. It inhibits HBV replication by merging into viral DNA via HBV reverse transcriptase, resulting in the termination of the DNA chain. This prevents the virus from producing new viruses and cleans up your infection.

No, Hepbest Tablet is a prescribed medication given by a physician for treating HBV infection or Chronic hepatitis B. It is recommended not to take it on your own.

Hepbest Tablet should be taken in the dose and for the duration prescribed by your doctor based on your medical condition.

The main symptoms include yellowing of eyes and skin, flu-like symptoms, pale stools and dark-coloured urine.

A blood test (HBsAg blood test) can be used to determine if you have hepatitis B or have ever had it.

Drug-Drug Interactions Checker List

  • TOBRAMYCIN
  • PENTAMIDINE
  • VANCOMYCIN
  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • ADEFOVIR
  • IBUPROFEN

Special Advise

  • If you take Hepbest Tablet , your doctor may regularly monitor liver function, kidney function, and bone density.

Disease/Condition Glossary

Hepatitis B: Hepatitis B is a potentially fatal liver infection caused by the hepatitis B virus (HBV). It is highly contagious (spreads from one person to another) and spreads by intimate contact with an infected individual, direct contact with infected blood, use of a contaminated needle, use of an infected razor/other personal objects, or transmission from mother to baby during birth. The virus can survive outside the body for up to 7 days. Chronic hepatitis B develops slowly, and symptoms may not be obvious until complications arise. Hepatitis B symptoms might occur three months after being exposed to the infection and can continue for two to twelve weeks. Chronic hepatitis B consequences include liver failure, liver cancer, and liver cirrhosis (scarring). Hepatitis B can be prevented by taking the vaccination.

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