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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Herduo Tablet 30's

Herduo Tablet 30's is an anti-cancer medicine used in the treatment of Breast cancer. The abnormal growth of cancer (malignant) cells in the breast is known as breast cancer. Herduo Tablet 30's is used in combination with capecitabine for treating patients with HER2-positive advanced or metastatic breast cancer who have received prior treatment, including anthracycline, taxane, and trastuzumab. This medicine is also used in combination with letrozole for the treatment of hormone receptor-positive metastatic breast cancer in patients with HER2-positive (human epidermal growth factor receptor 2) for whom hormonal therapy is indicated.

Herduo Tablet 30's contains Lapatinib as an active ingredient which belongs to the class of kinase inhibitors. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Herduo Tablet 30's may cause certain side effects such as diarrhea, fatigue, nausea, rash, indigestion, loss of appetite, headache, vomiting, weakness, mouth sores, hair loss, dry skin, myalgia, and allergic reactions. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. Herduo Tablet 30's should be taken as advised by your doctor. Take the medicine around the same time daily. Do not skip any dose; if you forget any dose, try to take it as soon as you remember unless it is time for your next dose. Do not double the dose.

Herduo Tablet 30's should be avoided if you are allergic to it or any other components of this medicine. Before starting the treatment, let your doctor know about your complete medical history and medication history, including vitamin and herbal supplements. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease before taking Herduo Tablet 30's. Herduo Tablet 30's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Composition

LAPATINIB-250MG

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Herduo Tablet 30's

Breast Cancer.

Medicinal Benefits

Herduo Tablet 30's contains Lapatinib as an active ingredient, which is used in combination with capecitabine for treating patients with HER2-positive advanced or metastatic breast cancer who have received prior treatment. This medicine works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Side Effects of Herduo Tablet 30's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Myalgia
  • Dry skin
  • Hair loss
  • Tiredness
  • Weakness
  • Headache
  • Fatigue

Directions for Use

Take Herduo Tablet 30's as prescribed by your doctor. It should be taken one hour before or at least one hour after. Swallow the medicine as a whole with a glass of water. Do not chew, crush, or break the medicine.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Herduo Tablet 30's should be avoided if you are allergic to it or any other components of this medicine. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Herduo Tablet 30's may cause left ventricular ejection fraction, prolonged QT interval, hepatotoxicity, interstitial lung disease, pneumonitis, severe diarrhoea, and hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Herduo Tablet 30's is known to cause embryo-fetal toxicity. Hence, if you are pregnant or planning to become pregnant, inform your doctor beforehand. Breastfeeding should be discontinued in nursing mothers during the treatment. Herduo Tablet 30's should be given to children only if prescribed by the paediatrician. Herduo Tablet 30's is not recommended for use in children as the safety and efficacy are not established. Avoid alcohol consumption and smoking, as it can lead to serious adverse effects.

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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LapatinibMoxifloxacin
Severe
LapatinibGatifloxacin
Severe

Drug-Drug Interactions

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LapatinibMoxifloxacin
Severe
How does the drug interact with Herduo Tablet 30's:
Using Moxifloxacin together with Herduo Tablet 30's can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Moxifloxacin and Herduo Tablet 30's, you can take these medicines together if prescribed by a doctor. If you experience irregular heart rhythm, dizziness, difficulty breathing, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LapatinibGatifloxacin
Severe
How does the drug interact with Herduo Tablet 30's:
Taking Gatifloxacin and Herduo Tablet 30's can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin and Herduo Tablet 30's together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LapatinibEscitalopram
Severe
How does the drug interact with Herduo Tablet 30's:
Combining Herduo Tablet 30's with Escitalopram can increase the risk of QTc prolongation.

How to manage the interaction:
Co-administration of Escitalopram with Herduo Tablet 30's can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience dizziness, fainting, abnormal heart rhythm, or difficulty breathing, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
LapatinibEnzalutamide
Severe
How does the drug interact with Herduo Tablet 30's:
When Herduo Tablet 30's is taken with Enzalutamide, this could reduce the effects of Herduo Tablet 30's and its blood levels. Additionally, taking these medications together may enhance enzalutamide's effects and blood levels.

How to manage the interaction:
Co-administration of Enzalutamide with Herduo Tablet 30's can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any of these symptoms - like Seizures, exhaustion, fatigue, constipation, discomfort in the muscles or bones, hot flushes, swelling, tingling or prickling, headaches, dizziness, sleeplessness, anxiety, and increased blood pressure, consult a doctor. Do not stop using any medications without talking to a doctor.
LapatinibClozapine
Severe
How does the drug interact with Herduo Tablet 30's:
When Clozapine is taken with Herduo Tablet 30's, can increase the risk of neutropenia (low white blood count).

How to manage the interaction:
Taking Clozapine with Herduo Tablet 30's together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away. You may also experience fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain, sudden dizziness, feeling lightheaded, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.
LapatinibCeritinib
Severe
How does the drug interact with Herduo Tablet 30's:
Taking Herduo Tablet 30's with ceritinib may significantly increase the blood levels of Herduo Tablet 30's. This can make you more likely to develop side effects such as diarrhea and liver problems.

How to manage the interaction:
Co-administration of Ceritinib with Herduo Tablet 30's can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
LapatinibPazopanib
Severe
How does the drug interact with Herduo Tablet 30's:
Taking Pazopanib with Herduo Tablet 30's may significantly increase the blood levels of pazopanib. This can make you more likely to develop serious side effects such as liver problems, irregular heart rhythm, bleeding and high blood pressure,

How to manage the interaction:
Taking Pazopanib with Herduo Tablet 30's together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.
LapatinibAmiodarone
Severe
How does the drug interact with Herduo Tablet 30's:
Coadministration of Amiodarone together with Herduo Tablet 30's may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Herduo Tablet 30's interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, get medical attention. Do not discontinue any medications without consulting a doctor.
LapatinibItraconazole
Severe
How does the drug interact with Herduo Tablet 30's:
Using Herduo Tablet 30's together with itraconazole may significantly increase the blood levels of Herduo Tablet 30's.

How to manage the interaction:
Herduo Tablet 30's and itraconazole may interact, but if a doctor prescribes them, you can still use them. If you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, fatigue, nausea, vomiting, dark urine, light stools, and yellowing of the skin or eyes, diarrhoea, dizziness, lightheadedness, fainting, shortness of breath, or rapid or pounding heartbeats, seek medical attention. Never discontinue taking a medication without consulting a doctor.
LapatinibSotalol
Severe
How does the drug interact with Herduo Tablet 30's:
Taking Sotalol and Herduo Tablet 30's can increase the risk or severity of irregular heart rhythms which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Although there is a possible interaction between Sotalol and Herduo Tablet 30's, you can take these medicines together if prescribed by a doctor. If you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • RITONAVIR
  • VERAMAPIL
  • DILTIAZEM
  • PHENYTOIN
  • PHENOBARBITAL
  • CARBAMAZEPINE
  • ST JOHN'S WORT
  • INDINAVIR
  • EFAVIRENZ
  • ITRACONAZOLE

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Special Advise

  • Avoid intercourse while on treatment with Herduo Tablet 30's.
  • Regular, complete blood count monitoring is advised during the treatment.
  • All patients should be tested for HER2 test before starting the treatment regimen.
  • Liver function tests (LFT) should be performed before starting the treatment and every 4 to 6 weeks during the treatment.
  • This medicine should be taken only once daily as prescribed by the doctor. Do not divide the dose of the medicine.
  • Regular ECG and electrolytes should be monitored while taking the medicine.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

Herduo Tablet 30's Substitute

Substitutes safety advice
  • Tykerb 250mg Tablet 30's

    by AYUR

    259.20per tablet
  • Combinib 250Mg Tablet 30'S

    by AYUR

    224.90per tablet
  • Tylidys Tablet 30's

    219.28per tablet
  • Libset Tablet 30's

    by AYUR

    163.86per tablet
  • TYKERB 250MG TABLET

    1189.00per tablet
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