Horn O Tablet 10's

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

MRP ₹100

(Inclusive of all Taxes)

₹15.0 Cashback (15%)

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Whats That

About Horn O Tablet

Horn O Tablet belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults.

Horn O Tablet is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Horn O Tablet helps in treating bacterial infections.

Take Horn O Tablet as prescribed. In some cases, Horn O Tablet may cause side-effects such as nausea, vomiting, abdominal pain, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.

Talk to your doctor if you experience pain in tendons, swelling, and inflammation as Horn O Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor before taking Horn O Tablet if you are pregnant or breastfeeding. Horn O Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Horn O Tablet as it may cause increased dizziness. Horn O Tablet is not recommended for use in children.

Uses of Horn O Tablet

Bacterial infections, Diarrhoea

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not chew, break or crush the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack; shake the pack well before each use.

Medicinal Benefits

Horn O Tablet belongs to the group of medicines called antibiotics used to treat urinary tract infections, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults. Horn O Tablet is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Horn O Tablet helps in treating bacterial infections. Horn O Tablet is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

Storage

Keep Horn O Tablet out of reach and sight of children.

Side effects of Horn O Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Trouble Falling/ Staying Asleep

Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:

Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
Try relaxing techniques like deep breathing, mindfulness meditation and any others.
Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Less Hunger

Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
Prefer foods high in fiber to help feel full for a long time.
If you have decreased appetite, eat only when you are hungry.
Eat several small meals or snacks all day.
Try to take only small sips of fluids while eating.

Drug Warnings

Do not take Horn O Tablet if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics; or if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor before taking Horn O Tablet if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes, rheumatoid arthritis, multiple sclerosis, heart, kidney or liver problems. Consult your doctor before taking Horn O Tablet if you are pregnant or breastfeeding. Horn O Tablet may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Horn O Tablet as it may cause increased dizziness.

Drug-Drug Interactions

OfloxacinQuinidine

Critical

OfloxacinHalofantrine

Critical

Drug-Drug Interactions

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OfloxacinQuinidine

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Quinidine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Horn O Tablet with Quinidine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

OfloxacinHalofantrine

Critical

How does the drug interact with Horn O Tablet:
Using halofantrine together with Horn O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Horn O Tablet with Halofantrine can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

OfloxacinDronedarone

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Dronedarone can increase the risk or severity of irregular heart rhythm.

How to manage the interaction:
Taking Horn O Tablet with Dronedarone together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

OfloxacinPimozide

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Pimozide can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Horn O Tablet with Pimozide together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

OfloxacinCisapride

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Horn O Tablet with Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market. Cisapride should only be taken if prescribed by a doctor and closely monitored.

OfloxacinBepridil

Critical

How does the drug interact with Horn O Tablet:
Using bepridil together with Horn O Tablet drugs can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Horn O Tablet with Bepridil can cause an interaction, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not stop using any medications without consulting a doctor.

OfloxacinSotalol

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Sotalol can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Horn O Tablet with Sotalol together is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor. Do not discontinue any medications without consulting a doctor.

OfloxacinMesoridazine

Critical

How does the drug interact with Horn O Tablet:
Using Mesoridazine together with Horn O Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Mesoridazine with Horn O Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.

OfloxacinSaquinavir

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Saquinavir can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Horn O Tablet with Saquinavir together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

OfloxacinThioridazine

Critical

How does the drug interact with Horn O Tablet:
Coadministration of Horn O Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Horn O Tablet with Thioridazine together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
Avoid consumption of alcohol and usage of tobacco.

Side Effects of Horn O Tablet

Nausea
Vomiting
Abdominal pain
Headache
Dizziness

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

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Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Jul 8, 2025 | 9:30 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Horn O Tablet work?

Horn O Tablet contains Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the production of DNA replication, transcription, and repair. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Horn O Tablet helps in treating bacterial infections.

Does Horn O Tablet cause photosensitivity?

Horn O Tablet may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.

Can I stop taking Horn O Tablet on my own?

It is recommended to complete the course of Horn O Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Horn O Tablet for as long as your doctor has prescribed it.

Can I take antacids with Horn O Tablet ?

Co-administration of magnesium and aluminium-containing antacids, sucralfate, and iron-containing preparations with Horn O Tablet may reduce the absorption. Therefore, you are advised to take Horn O Tablet two hours before such preparations.

Can I take Horn O Tablet on my own?

Do not take Horn O Tablet on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.

I am diabetic, can I take Horn O Tablet ?

Consult your doctor before taking Horn O Tablet if you have diabetes, as Horn O Tablet may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Horn O Tablet to avoid unpleasant events.

Drug-Drug Interactions Checker List

ASPIRIN
IBUPROFEN
AZITHROMYCIN
TRIMETHOPRIM+SULFAMETHOXAZOLE
METRONIDAZOLE
ERYTHROMYCIN
DEXAMETHASONE
METFORMIN
ALBUTEROL
FUROSEMIDE

Special Advise

Horn O Tablet may affect coagulation test or prothrombin time (time is taken for blood clotting), liver function tests, and serum tests. Horn O Tablet contains ofloxacin which might produce false-positive urine screening results for opiates. Inform the person doing the tests that you are taking Horn O Tablet .
Horn O Tablet is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Horn O Tablet .

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. It can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.

Diarrhoea: Diarrhoea is the condition in which there is a frequent need to empty the bowels. It is characterized by loose and watery stools. The causes of diarrhoea include food intolerance, food allergy, adverse reaction to any medicine, viral infection, bacterial infection, intestinal disease, parasitic infection, and stomach or gallbladder surgery. The symptoms of diarrhoea include nausea, abdominal pain/cramps, dehydration, bloating, frequent urge to empty the bowels, and a large volume of stools or watery stools.