Ofloxacin+ornidazole
About
Ofloxacin+ornidazole belongs to the group of medicines called antibiotics used to treat bacterial infections of the urinary tract, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults.
Ofloxacin+ornidazole is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Ofloxacin+ornidazole helps in treating bacterial infections.
Take Ofloxacin+ornidazole as prescribed. In some cases, Ofloxacin+ornidazole may cause side-effects such as nausea, vomiting, abdominal pain, headache, and dizziness. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side-effects persist or worsen.
Talk to your doctor if you experience pain in tendons, swelling, and inflammation as Ofloxacin+ornidazole is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor before taking Ofloxacin+ornidazole if you are pregnant or breastfeeding. Ofloxacin+ornidazole may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Ofloxacin+ornidazole as it may cause increased dizziness. Ofloxacin+ornidazole is not recommended for use in children.
Uses of Ofloxacin+ornidazole
Medicinal Benefits
Ofloxacin+ornidazole belongs to the group of medicines called antibiotics used to treat urinary tract infections, bacterial infections by inflammation of the peritoneum, eye and ear infections, skin and soft tissue infections, sexually transmitted infections, respiratory infections, vaginal infections, protozoan infections, intra-abdominal infections, and infections during surgical procedures. It is also indicated in the treatment of diarrhoea of mixed infections in adults. Ofloxacin+ornidazole is a combination of two antibiotic drugs, namely: Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the replication, transcription, and repair of the DNA. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Ofloxacin+ornidazole helps in treating bacterial infections. Ofloxacin+ornidazole is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.
Directions for Use
Storage
Side Effects of Ofloxacin+ornidazole
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
In-Depth Precautions and Warning
Drug Warnings
Do not take Ofloxacin+ornidazole if you are allergic to any of its contents; if you had swelling or tearing of tendons while taking quinolone antibiotics; or if you have myasthenia gravis, as it may cause increased muscle weakness. Talk to your doctor before taking Ofloxacin+ornidazole if you have epilepsy, low levels of potassium, nervous or muscle problems, head injury or brain tumour, diabetes, rheumatoid arthritis, multiple sclerosis, heart, kidney or liver problems. Consult your doctor before taking Ofloxacin+ornidazole if you are pregnant or breastfeeding. Ofloxacin+ornidazole may cause dizziness and drowsiness, so drive only if you are alert. Avoid alcohol consumption while taking Ofloxacin+ornidazole as it may cause increased dizziness.
Drug Interactions
Drug-Drug Interactions: Ofloxacin+ornidazole may interact with pain killers (aspirin, ibuprofen), antibiotics (azithromycin, sulfamethoxazole, trimethoprim, metronidazole, erythromycin), corticosteroids (dexamethasone), anti-diabetic (metformin), bronchodilator (albuterol), and diuretics (furosemide).
Drug-Food Interactions: Avoid consuming milk and dairy products.
Drug-Disease Interactions: Inform your doctor if you have colitis (inflammation in the lining of the colon), tendonitis (inflammation in tendons), CNS disorders, myasthenia gravis (neuromuscular disease), peripheral neuropathy (nerve pain), crystalluria (cloudy urine), diabetes, kidney, liver and heart problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consuming alcohol while taking Ofloxacin+ornidazole as it may cause increased dizziness.
Pregnancy
cautionPlease consult your doctor if you are pregnant; your doctor will prescribe Ofloxacin+ornidazole only if the benefits outweigh the risks.
Breast Feeding
cautionConsult your doctor before taking Ofloxacin+ornidazole if you are breastfeeding. Your doctor will decide if Ofloxacin+ornidazole can be taken by breastfeeding mothers or not.
Driving
cautionOfloxacin+ornidazole may cause dizziness and drowsiness. So, drive only if you are alert.
Liver
cautionDose adjustment may be needed. Please consult your doctor before taking Ofloxacin+ornidazole if you have liver impairment/liver disease.
Kidney
cautionPlease consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking Ofloxacin+ornidazole.
Children
unsafeOfloxacin+ornidazole is not recommended for children as safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
- Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
- Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
- Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
- Avoid consumption of alcohol and usage of tobacco.
Special Advise
- Ofloxacin+ornidazole may affect coagulation test or prothrombin time (time is taken for blood clotting), liver function tests, and serum tests. Ofloxacin+ornidazole contains ofloxacin which might produce false-positive urine screening results for opiates. Inform the person doing the tests that you are taking Ofloxacin+ornidazole.
- Ofloxacin+ornidazole is associated with an increased risk of tendon rupture and tendonitis. Consult your doctor immediately if you experience tendon pain, swelling or inflammation while taking Ofloxacin+ornidazole.
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Harmful bacteria produce chemicals known as toxins, which can damage tissue and cause sickness. It can target any body part and multiply very quickly. Symptoms include fever, chills, and fatigue. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicine are more prone to bacterial infection.
Diarrhoea: Diarrhoea is the condition in which there is a frequent need to empty the bowels. It is characterized by loose and watery stools. The causes of diarrhoea include food intolerance, food allergy, adverse reaction to any medicine, viral infection, bacterial infection, intestinal disease, parasitic infection, and stomach or gallbladder surgery. The symptoms of diarrhoea include nausea, abdominal pain/cramps, dehydration, bloating, frequent urge to empty the bowels, and a large volume of stools or watery stools.
FAQs
Ofloxacin+ornidazole contains Ofloxacin and Ornidazole. Ofloxacin inhibits DNA gyrase which is required for the production of DNA replication, transcription, and repair. Ornidazole inhibits protein synthesis and leads to cell death, thereby kills the bacteria. Together, Ofloxacin+ornidazole helps in treating bacterial infections.
Ofloxacin+ornidazole may cause photosensitivity (sensitivity to sunlight) and can make you sunburn easily. Avoid prolonged exposure to sunlight or tanning beds. Always wear protective clothing and sunscreen with SPF 30 or higher before going out.
It is recommended to complete the course of Ofloxacin+ornidazole even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Ofloxacin+ornidazole for as long as your doctor has prescribed it.
Co-administration of magnesium and aluminium-containing antacids, sucralfate, and iron-containing preparations with Ofloxacin+ornidazole may reduce the absorption. Therefore, you are advised to take Ofloxacin+ornidazole two hours before such preparations.
Do not take Ofloxacin+ornidazole on your own as self-medication may lead to antibiotic-resistance in which antibiotics fail to act against specific bacterial infections.
Consult your doctor before taking Ofloxacin+ornidazole if you have diabetes, as Ofloxacin+ornidazole may cause hypoglycaemia (low blood sugar levels). Regularly monitor blood sugar levels while taking Ofloxacin+ornidazole to avoid unpleasant events.
