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Composition :

HYDROXYUREA-500MG

Manufacturer/Marketer :

Zee Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Hydrozest 500 mg Capsule

Hydrozest 500 mg Capsule belongs to a group of classes known as an antimetabolite. It is an anticancer medicine used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). Head and neck cancer is a disease including abnormal growth of the tissues of the neck and head that may also have the ability to attack or spread to other portions of the body. Sickle cell anemia is a disease in which your body results in abnormally shaped red blood cells. The cells are shaped like a curved or sickle.

In cancer, Hydrozest 500 mg Capsule works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

Take Hydrozest 500 mg Capsule as prescribed by your doctor. You are advised to take Hydrozest 500 mg Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience loss of appetite (feeling unwell and stomach upset), Increased bleeding tendency, nausea, upset stomach, vomiting. Most of these side effects of Hydrozest 500 mg Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before starting Hydrozest 500 mg Capsule , please inform your doctor if you have any allergy, kidney disease, liver disease, injury on your legs, HIV or AIDS, high level of uric acid in your blood, and treatment with chemotherapy or radiation. Hydrozest 500 mg Capsule may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Hydrozest 500 mg Capsule can cause harmful effects on the unborn baby. Both women and men using this Hydrozest 500 mg Capsule should use birth control to avoid pregnancy. The use of this Hydrozest 500 mg Capsule by either parent may results in birth defects. You should not take this Hydrozest 500 mg Capsule during breastfeeding, inform your doctor if you take Hydrozest 500 mg Capsule .

Uses of Hydrozest 500 mg Capsule

Head and neck cancer and sickle cell anemia (blocking flow of blood that causes pain and organ damage).

Directions for Use

Take Hydrozest 500 mg Capsule as advised by the doctor. Swallow it as a whole with water. Do not crush, break or chew it. Wash your hands before and after handling the bottle containing Hydrozest 500 mg Capsule . Crushed or broken pill can be unsafe if it gets in your mouth, nose, eyes, or on your skin. If this happens, wash your skin with water and soap or wash your eyes with water.

Medicinal Benefits

Hydrozest 500 mg Capsule belongs to a group of the class known as an antimetabolite. It is used to treat head and neck cancer and sickle cell anemia (blocking the flow of blood that causes pain and organ damage). In cancer, Hydrozest 500 mg Capsule works by blocking an enzyme that is required for growing cells. This prevents the cancer cells from multiplying and growing. In sickle cell disease, it works by increasing fetal hemoglobin (HbF) (hemoglobin of unborn baby) levels in red blood cells (RBCs). This helps the RBCs accept a normal shape, recovers the flow of blood, and protects against problems like painful sickle cell attacks.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking Hydrozest 500 mg Capsule inform your doctor if you have any kind of infection because Hydrozest 500 mg Capsule may worsen the infections. Talk to your doctor if you have any allergy symptoms. Kidney disease, liver disease, injury on your legs, HIV or AIDS, high level of uric acid in your blood, and treatment with chemotherapy or radiation inform your doctor. Hydrozest 500 mg Capsule may increase the chances of other cancer. Inform your doctor about this risk. Immediately contact your doctor if you are pregnant because this Hydrozest 500 mg Capsule can cause harmful effects on the unborn baby. Both women and men using this Hydrozest 500 mg Capsule should use birth control to avoid pregnancy. The use of this Hydrozest 500 mg Capsule by either parent may result in birth defects. You should not take this Hydrozest 500 mg Capsule during breastfeeding, inform your doctor if you take Hydrozest 500 mg Capsule . If any powder from a damaged pill is leaked, wash it up at once with a wet paper towel and throw the towel away in a closed plastic bag where children cannot get to it.

Drug-Drug Interactions

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HydroxycarbamideCertolizumab
Severe
HydroxycarbamideChloroprocaine
Severe

Drug-Drug Interactions

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HydroxycarbamideCertolizumab
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Hydrozest 500 mg Capsule when used with certolizumab may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydrozest 500 mg Capsule with certolizumab, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideChloroprocaine
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Chloroprocaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydrozest 500 mg Capsule, which may lead to methemoglobinemia.

How to manage the interaction:
Although taking Hydrozest 500 mg Capsule and chloroprocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideClozapine
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Taking Hydrozest 500 mg Capsule and Clozapine can increase the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Hydrozest 500 mg Capsule, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor.
HydroxycarbamideVoclosporin
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Hydrozest 500 mg Capsule when used with voclosporin may raise the risk of severe infections, some kinds of cancer, including skin cancer and cancer of the lymph glands (lymphoma).

How to manage the interaction:
There may be a possibility of interaction between Hydrozest 500 mg Capsule with voclosporin, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxycarbamideEtidocaine
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Etidocaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydrozest 500 mg Capsule, which may also lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficit may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydrozest 500 mg Capsule and Etidocaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideProcaine
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Procaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydrozest 500 mg Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydrozest 500 mg Capsule and procaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideRopivacaine
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Ropivacaine has the potential to cause methemoglobinemia (a rare disorder in which the iron in the haemoglobin molecule (the red blood pigment) is defective, preventing it from carrying oxygen to the tissues adequately). This risk increases when used with Hydrozest 500 mg Capsule, which may lead to methemoglobinemia. When taking these drugs, those who are extremely young (particularly newborns and babies), have heart or lung conditions, certain genetic predispositions, or have a glucose-6-phosphate dehydrogenase deficiencies may be more likely to develop methemoglobinemia.

How to manage the interaction:
Although taking Hydrozest 500 mg Capsule and ropivacaine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as grey discolouration of the skin, abnormal blood colouration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxycarbamideNatalizumab
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Taking Hydrozest 500 mg Capsule with natalizumab, especially taking both simultaneously, may raise the risk of serious infections, which may lead to infections like progressive multifocal leukoencephalopathy (PML), an uncommon but dangerous viral infection of the brain that can result in impairment.

How to manage the interaction:
Co-administration of Hydrozest 500 mg Capsule with natalizumab can possibly result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you are experience fever, chills, diarrhoea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. If you have growing weakness on one side of your body, awkwardness of limbs, visual disruption, disorientation, or changes in thinking, memory, or personality, inform your doctor.
HydroxycarbamideDidanosine
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Combining Hydrozest 500 mg Capsule with didanosine can have serious consequences on your liver or pancreas. Didanosine may potentially induce lactic acidosis (lactic acid buildup in the body).Lactic acidosis can develop gradually and worsen over time.

How to manage the interaction:
Co-administration of Hydrozest 500 mg Capsule with didanosine can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you have any of the following symptoms while taking didanosine: strong discomfort in your upper stomach that spreads to your back, rapid heart rate, nausea and vomiting, diarrhoea, lack of appetite, low fever, dark urine, clay-colored faeces, or jaundice (yellowing of the skin or eyes), unusual muscle pain and weakness, trouble breathing, fast or uneven heart rate, stomach pain, and numbness or cold feeling in your arms or legs, contact the doctor immediately.
HydroxycarbamideEtanercept
Severe
How does the drug interact with Hydrozest 500 mg Capsule:
Hydrozest 500 mg Capsule when used in conjunction with etanercept may raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Hydrozest 500 mg Capsule with etanercept, but it can be taken if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take Hydrozest 500 mg Capsule at the same time daily, either with or without a meal.
  • It is recommended to remain hydrated and drink a lot of fluids while taking Hydrozest 500 mg Capsule .
  • Do not miss any dose and finish the course as recommended by your doctor.
  • Use an efficient method of birth control to prevent pregnancy while taking this Hydrozest 500 mg Capsule .
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, blood cell count in your blood.

Habit Forming

No

Therapeutic Class

ANTIMETABOLITES

Hydrozest 500 mg Capsule Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Take the Hydrozest 500 mg Capsule as soon as you can but avoid the missed dose if it is nearly time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of Hydrozest 500 mg Capsule entirely.

Immediately go to the emergency department of your nearest hospital. Be ready to tell or show what was taken, how much, and when it happened.

Hydrozest 500 mg Capsule may cause a risk of skin cancer. Avoid contact with sunlight or tanning beds. Wear protective cloth and use sunscreen (SPF 30 or higher) when you are outside. Do not handle Hydrozest 500 mg Capsule without the protection of skin.

Hydrozest 500 mg Capsule can cause dizziness and drowsiness during the first limited hours after you take it. These side effects are more expected to happen when you start taking Hydrozest 500 mg Capsule or when your doctor increases your dose.

Do not stop taking Hydrozest 500 mg Capsule without discussing it with your doctor. Your doctor will most likely tell you to take another medicine, folic acid (a vitamin), to reduce some of the side effects of this Hydrozest 500 mg Capsule . Take this Hydrozest 500 mg Capsule exactly as instructed.

Drug-Drug Interactions Checker List

  • DIDANOSINE
  • INDINAVIR
  • ASPIRIN
  • IBUPROFEN
  • DIPHENHYDRAMINE
  • ALLOPURINOL
  • ZOLPIDEM

Special Advise

  • Wash your hands before and after handling the bottle containing Hydrozest 500 mg Capsule .
  • Crushed or broken pill can be unsafe if it gets in your mouth, nose, eyes, or on your skin. If this happens, wash your skin with water and soap or wash your eyes with water.

Disease/Condition Glossary

Head and neck cancer: It is a disease including abnormal growth of the tissues of the neck and head that may also have the ability to attack or spread to other portions of the body. Cancer of the head and neck generally starts in the cells known as squamous cells which appear in the lining of the surface of moist mucosa in the head and neck (e.g., inside of the throat, nose, and mouth).

Sickle cell anemia: It is a disease in which your body results in abnormally shaped red blood cells. The cells are shaped like a curved or sickle. They do not last as long as round, normal, red blood cells. This causes anemia. The sickle cells also get pushed into blood vessels, blocking the flow of blood. This can result in pain and organ damage.

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